Association between anxiety state and mitral valve disorders: A Taiwanese population-wide observational study

Navneet Kumar Dubey, Shabbir Syed-Abdul, Phung Anh Nguyen, Rajni Dubey, Iqbal Usman, Yu Chuan Li, Wei Hong Chen, Win Ping Deng

研究成果: 雜誌貢獻文章

1 引文 (Scopus)

摘要

Background and objective: Despite substantial research progress in concurrent diseases, for instance comorbidities involving anxiety state (AS) and mitral valve disorders (MVD), the current measures and care are limited and no consensus about their association has yet been reached. Hence, this study aims to analyze the prevalence and association between AS and MVD among Taiwanese population. Methods: We employed phenome-wide association study (PWAS) portal to investigate the association between AS and MVD using claim data of Taiwan's National Health Insurance Research Database (NHIRD) from year 2000 to 2002. Association strength between AS and MVD was analyzed among overall age and gender groups. Results: We found an overall stronger association between AS and MVD, which was significantly higher in younger age group (OR 15, 95% CI 14.82-16.88) than in the elderly age group (OR 1.99, 95% CI 1.76-2.24). Also, the study reveals a higher incidence of co-occurrence in females than males, particularly in age group of 40-49. Conclusions: Based on our results showing considerable strength of association between AS and MVD, this study suggests the necessity of MVD assessment in all patients with AS, particularly in younger females. Moreover, we also propose psychotherapeutic as well as pharmacologic intervention for comorbidity-based pathologies to better the quality care for high-need Taiwanese population.
原文英語
頁(從 - 到)57-61
頁數5
期刊Computer Methods and Programs in Biomedicine
132
DOIs
出版狀態已發佈 - 八月 1 2016

指紋

Mitral Valve
Observational Studies
Anxiety
Health insurance
Pathology
Population
Age Groups
Comorbidity
Quality of Health Care
National Health Programs
Taiwan
Research
Consensus
Databases
Incidence

ASJC Scopus subject areas

  • Computer Science Applications
  • Software
  • Health Informatics

引用此文

Association between anxiety state and mitral valve disorders : A Taiwanese population-wide observational study. / Dubey, Navneet Kumar; Syed-Abdul, Shabbir; Nguyen, Phung Anh; Dubey, Rajni; Usman, Iqbal; Li, Yu Chuan; Chen, Wei Hong; Deng, Win Ping.

於: Computer Methods and Programs in Biomedicine, 卷 132, 01.08.2016, p. 57-61.

研究成果: 雜誌貢獻文章

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abstract = "Background and objective: Despite substantial research progress in concurrent diseases, for instance comorbidities involving anxiety state (AS) and mitral valve disorders (MVD), the current measures and care are limited and no consensus about their association has yet been reached. Hence, this study aims to analyze the prevalence and association between AS and MVD among Taiwanese population. Methods: We employed phenome-wide association study (PWAS) portal to investigate the association between AS and MVD using claim data of Taiwan's National Health Insurance Research Database (NHIRD) from year 2000 to 2002. Association strength between AS and MVD was analyzed among overall age and gender groups. Results: We found an overall stronger association between AS and MVD, which was significantly higher in younger age group (OR 15, 95{\%} CI 14.82-16.88) than in the elderly age group (OR 1.99, 95{\%} CI 1.76-2.24). Also, the study reveals a higher incidence of co-occurrence in females than males, particularly in age group of 40-49. Conclusions: Based on our results showing considerable strength of association between AS and MVD, this study suggests the necessity of MVD assessment in all patients with AS, particularly in younger females. Moreover, we also propose psychotherapeutic as well as pharmacologic intervention for comorbidity-based pathologies to better the quality care for high-need Taiwanese population.",
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AU - Dubey, Navneet Kumar

AU - Syed-Abdul, Shabbir

AU - Nguyen, Phung Anh

AU - Dubey, Rajni

AU - Usman, Iqbal

AU - Li, Yu Chuan

AU - Chen, Wei Hong

AU - Deng, Win Ping

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N2 - Background and objective: Despite substantial research progress in concurrent diseases, for instance comorbidities involving anxiety state (AS) and mitral valve disorders (MVD), the current measures and care are limited and no consensus about their association has yet been reached. Hence, this study aims to analyze the prevalence and association between AS and MVD among Taiwanese population. Methods: We employed phenome-wide association study (PWAS) portal to investigate the association between AS and MVD using claim data of Taiwan's National Health Insurance Research Database (NHIRD) from year 2000 to 2002. Association strength between AS and MVD was analyzed among overall age and gender groups. Results: We found an overall stronger association between AS and MVD, which was significantly higher in younger age group (OR 15, 95% CI 14.82-16.88) than in the elderly age group (OR 1.99, 95% CI 1.76-2.24). Also, the study reveals a higher incidence of co-occurrence in females than males, particularly in age group of 40-49. Conclusions: Based on our results showing considerable strength of association between AS and MVD, this study suggests the necessity of MVD assessment in all patients with AS, particularly in younger females. Moreover, we also propose psychotherapeutic as well as pharmacologic intervention for comorbidity-based pathologies to better the quality care for high-need Taiwanese population.

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KW - Anxiety

KW - Comorbidity

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