Assisted ventilation in infants with meconium aspiration syndrome

Dh Vidyasagar, T. F. Yeh, V. Harris, R. S. Pildes

研究成果: 雜誌貢獻文章

46 引文 (Scopus)

摘要

In a retrospective analysis of infants born with meconium staining over an 18 month period 32 infants met two of the three criteria for the diagnosis of meconium aspiration syndrome: (1) history of meconium in the oropharynx or trachea; (2) clinical evidence of respiratory distress; and (3) x ray evidence of aspiration pneumonia. Seventeen infants developed respiratory failure; nine of these infants died. One infant without respiratory failure died of sepsis. Analysis of sequential arterial blood pH and gas tension showed that nonsurviving infants had persistently high pCO2 and A-a gradient in spite of initiation of assisted ventilation. These changes seem to be related to severe right to left shunting and ventilation perfusion abnormalities. The data further suggest that asphyxia and acidosis occur well before the infant is born and that intrapartum monitoring to recognize fetal asphyxia may help in improving morbidity and mortality from meconium aspiration syndrome.

原文英語
頁(從 - 到)208-213
頁數6
期刊Pediatrics
56
發行號2
出版狀態已發佈 - 十二月 1 1975
對外發佈Yes

指紋

Meconium Aspiration Syndrome
Ventilation
Meconium
Asphyxia
Respiratory Insufficiency
Aspiration Pneumonia
Oropharynx
Acidosis
Trachea
Sepsis
Perfusion
Gases
X-Rays
Staining and Labeling
Morbidity
Mortality

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

引用此文

Vidyasagar, D., Yeh, T. F., Harris, V., & Pildes, R. S. (1975). Assisted ventilation in infants with meconium aspiration syndrome. Pediatrics, 56(2), 208-213.

Assisted ventilation in infants with meconium aspiration syndrome. / Vidyasagar, Dh; Yeh, T. F.; Harris, V.; Pildes, R. S.

於: Pediatrics, 卷 56, 編號 2, 01.12.1975, p. 208-213.

研究成果: 雜誌貢獻文章

Vidyasagar, D, Yeh, TF, Harris, V & Pildes, RS 1975, 'Assisted ventilation in infants with meconium aspiration syndrome', Pediatrics, 卷 56, 編號 2, 頁 208-213.
Vidyasagar D, Yeh TF, Harris V, Pildes RS. Assisted ventilation in infants with meconium aspiration syndrome. Pediatrics. 1975 12月 1;56(2):208-213.
Vidyasagar, Dh ; Yeh, T. F. ; Harris, V. ; Pildes, R. S. / Assisted ventilation in infants with meconium aspiration syndrome. 於: Pediatrics. 1975 ; 卷 56, 編號 2. 頁 208-213.
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