Assessment of left ventricular end-systolic elastance from aortic pressure-left ventricular volume relations

Wen Shin Lee, Masaru Nakayama, Wen Pin Huang, Kuan Rau Chiou, Chih Cheng Wu, Erez Nevo, Barry Fetics, David A. Kass, Philip Yu An Ding, C. H. Chen

研究成果: 雜誌貢獻文章同行評審

11 引文 斯高帕斯(Scopus)

摘要

The left ventricular (LV) end-systolic pressure-volume relation (ESPVR) is a load-insensitive method for evaluating LV contractility, which needs invasive measurement. Some noninvasive methods substitute peak aortic pressure (Ps) for end-systolic LV pressure by assuming there is no difference between these pressures. However, this assumption has not been directly validated. With conductance catheter and dual micromanometers, ESPVRs and the slope (EesLV) were constructed from simultaneous LV pressures (LVP) and volumes, aortic pressures (AOP) and LV volumes (EesAO), and Ps and LV end-ejection volumes (VEE) (EesPP-EEV) during preload reduction in 50 subjects. The ratio of steady-state Ps over VEE (Ps/VEE) was also checked. AOP and LVP displayed differences of 11 ± 6 and -30 ± 12 mmHg at the onset and end-ejection, respectively, and -2 ± 4 mmHg at end-systole. EesAO and EesLV were nearly identical: EesAO = 0.97 × EesLV + 0.05, r2 = 0.99. EesPP-EEV correlated with EesLV (EesPP-EEV = 0.57 × EesLV + 0.61, r2 = 0.46) but with much more scatter. Ps/VEE correlated worst with EesLV. Central AOP can be substituted for LVP to derive EesLV. Other estimation methods yield weaker and poor correlations to directly measured Ees.
原文英語
頁(從 - 到)99-104
頁數6
期刊Heart and Vessels
16
發行號3
DOIs
出版狀態已發佈 - 五月 14 2002
對外發佈

ASJC Scopus subject areas

  • 心臟病學與心血管醫學

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