Arterial stiffness index and coronary artery plaques in patients with subclinical coronary atherosclerosis

研究成果: 雜誌貢獻文章

5 引文 (Scopus)

摘要

Background: Arterial stiffness is a physiologic quantitative value used to measure arterial compliance. It is predictive of coronary atherosclerosis in patients with intermediate to high cardiovascular risk. However, a correlation between arterial stiffness and subclinical coronary atherosclerosis has yet to be established. Therefore, the purpose of this study was to evaluate arterial stiffness using an arterial stiffness index (ASI) and investigate its association with coronary artery plaque in patients with subclinical coronary atherosclerosis. Methods: Our study enrolled 156 consecutive subjects who underwent health screening using a 64-slice cardiac computed tomography angiography (CCTA). Their arterial stiffness index was assessed noninvasively by CardioVision® MS-2000. The atheroma on the coronary vessel walls was analyzed. Results: Of the 156 patients, 53 displayed at least one > 50% stenotic lesion over the coronary arteries in CCTA images. The patients with at least one > 50% coronary stenotic plaque were older and had higher systolic blood pressure and ASI values than patients without > 50% coronary stenotic plaque. After dividing the study population into 2 groups by those patients over and under 50 years of age, the ASI positively correlated with the presentation of at least one > 50% coronary stenotic plaque in patients aged ≥ 50 years (odds ratio = 1.02, 95% confidence interval: 1.00-1.04, p = 0.03). Conclusions: The ASI could play a role in risk stratification systems for coronary artery disease in patients with subclinical coronary atherosclerosis, and is a useful clinical marker for the correlation of early coronary plaque.
原文英語
頁(從 - 到)59-65
頁數7
期刊Acta Cardiologica Sinica
31
發行號1
DOIs
出版狀態已發佈 - 一月 1 2015

指紋

Vascular Stiffness
Coronary Artery Disease
Coronary Vessels
Atherosclerotic Plaques
Compliance
Biomarkers
Odds Ratio
Confidence Intervals
Blood Pressure
Hypertension
Health

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

引用此文

@article{10a6f722951d4ccba826972a0a7f0757,
title = "Arterial stiffness index and coronary artery plaques in patients with subclinical coronary atherosclerosis",
abstract = "Background: Arterial stiffness is a physiologic quantitative value used to measure arterial compliance. It is predictive of coronary atherosclerosis in patients with intermediate to high cardiovascular risk. However, a correlation between arterial stiffness and subclinical coronary atherosclerosis has yet to be established. Therefore, the purpose of this study was to evaluate arterial stiffness using an arterial stiffness index (ASI) and investigate its association with coronary artery plaque in patients with subclinical coronary atherosclerosis. Methods: Our study enrolled 156 consecutive subjects who underwent health screening using a 64-slice cardiac computed tomography angiography (CCTA). Their arterial stiffness index was assessed noninvasively by CardioVision{\circledR} MS-2000. The atheroma on the coronary vessel walls was analyzed. Results: Of the 156 patients, 53 displayed at least one > 50{\%} stenotic lesion over the coronary arteries in CCTA images. The patients with at least one > 50{\%} coronary stenotic plaque were older and had higher systolic blood pressure and ASI values than patients without > 50{\%} coronary stenotic plaque. After dividing the study population into 2 groups by those patients over and under 50 years of age, the ASI positively correlated with the presentation of at least one > 50{\%} coronary stenotic plaque in patients aged ≥ 50 years (odds ratio = 1.02, 95{\%} confidence interval: 1.00-1.04, p = 0.03). Conclusions: The ASI could play a role in risk stratification systems for coronary artery disease in patients with subclinical coronary atherosclerosis, and is a useful clinical marker for the correlation of early coronary plaque.",
keywords = "Arterial stiffness, Arterial stiffness index, Atherosclerosis, Coronary artery plaque",
author = "Kao, {Yung Ta} and Wang, {Sen Te} and Shih, {Chun Ming} and Lin, {Feng Yen} and Tsao, {Nai Wen} and Chiang, {Kuang Hsing} and Chan, {Chao Shun} and Lin, {Yen Chung} and Hung, {Ming Yow} and Hsieh, {Ming Hsiung} and Shyu, {Kuo Gi} and Chen, {Jaw Wen} and Chang, {Nen Chung} and Yeh, {Jong Shiuan} and Huang, {Chun Yao}",
year = "2015",
month = "1",
day = "1",
doi = "10.6515/ACS20140630B",
language = "English",
volume = "31",
pages = "59--65",
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T1 - Arterial stiffness index and coronary artery plaques in patients with subclinical coronary atherosclerosis

AU - Kao, Yung Ta

AU - Wang, Sen Te

AU - Shih, Chun Ming

AU - Lin, Feng Yen

AU - Tsao, Nai Wen

AU - Chiang, Kuang Hsing

AU - Chan, Chao Shun

AU - Lin, Yen Chung

AU - Hung, Ming Yow

AU - Hsieh, Ming Hsiung

AU - Shyu, Kuo Gi

AU - Chen, Jaw Wen

AU - Chang, Nen Chung

AU - Yeh, Jong Shiuan

AU - Huang, Chun Yao

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Background: Arterial stiffness is a physiologic quantitative value used to measure arterial compliance. It is predictive of coronary atherosclerosis in patients with intermediate to high cardiovascular risk. However, a correlation between arterial stiffness and subclinical coronary atherosclerosis has yet to be established. Therefore, the purpose of this study was to evaluate arterial stiffness using an arterial stiffness index (ASI) and investigate its association with coronary artery plaque in patients with subclinical coronary atherosclerosis. Methods: Our study enrolled 156 consecutive subjects who underwent health screening using a 64-slice cardiac computed tomography angiography (CCTA). Their arterial stiffness index was assessed noninvasively by CardioVision® MS-2000. The atheroma on the coronary vessel walls was analyzed. Results: Of the 156 patients, 53 displayed at least one > 50% stenotic lesion over the coronary arteries in CCTA images. The patients with at least one > 50% coronary stenotic plaque were older and had higher systolic blood pressure and ASI values than patients without > 50% coronary stenotic plaque. After dividing the study population into 2 groups by those patients over and under 50 years of age, the ASI positively correlated with the presentation of at least one > 50% coronary stenotic plaque in patients aged ≥ 50 years (odds ratio = 1.02, 95% confidence interval: 1.00-1.04, p = 0.03). Conclusions: The ASI could play a role in risk stratification systems for coronary artery disease in patients with subclinical coronary atherosclerosis, and is a useful clinical marker for the correlation of early coronary plaque.

AB - Background: Arterial stiffness is a physiologic quantitative value used to measure arterial compliance. It is predictive of coronary atherosclerosis in patients with intermediate to high cardiovascular risk. However, a correlation between arterial stiffness and subclinical coronary atherosclerosis has yet to be established. Therefore, the purpose of this study was to evaluate arterial stiffness using an arterial stiffness index (ASI) and investigate its association with coronary artery plaque in patients with subclinical coronary atherosclerosis. Methods: Our study enrolled 156 consecutive subjects who underwent health screening using a 64-slice cardiac computed tomography angiography (CCTA). Their arterial stiffness index was assessed noninvasively by CardioVision® MS-2000. The atheroma on the coronary vessel walls was analyzed. Results: Of the 156 patients, 53 displayed at least one > 50% stenotic lesion over the coronary arteries in CCTA images. The patients with at least one > 50% coronary stenotic plaque were older and had higher systolic blood pressure and ASI values than patients without > 50% coronary stenotic plaque. After dividing the study population into 2 groups by those patients over and under 50 years of age, the ASI positively correlated with the presentation of at least one > 50% coronary stenotic plaque in patients aged ≥ 50 years (odds ratio = 1.02, 95% confidence interval: 1.00-1.04, p = 0.03). Conclusions: The ASI could play a role in risk stratification systems for coronary artery disease in patients with subclinical coronary atherosclerosis, and is a useful clinical marker for the correlation of early coronary plaque.

KW - Arterial stiffness

KW - Arterial stiffness index

KW - Atherosclerosis

KW - Coronary artery plaque

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