Applications of cyclic peptide nanotubes (cPNTs)

Wei Hsien Hsieh, Jiahorng Liaw

研究成果: 雜誌貢獻文章同行評審

16 引文 斯高帕斯(Scopus)

摘要

Self-assembled cyclic peptide nanotubes (cPNTs) have recently drawn particular attention as one of the most intriguing nanostructures in the field of nanotechnology. Given their unique features including high surface area, increased drug loading, environmental stability, enhanced permeation, and modifiable drug release, these hollow tubular structures can be constructed with cyclic di-, tri-, tetra-, hexa-, octa-, and decapeptides with various amino acid sequences, enantiomers, and functionalized side chains and can be applied for antiviral and antibacterial drugs, drug delivery and gene delivery vectors, organic electronic devices, and ionic or molecular channels. Recent publications have presented promising results regarding the use of cPNTs as drugs or biomedical devices. However, there is an urgent need for the further in vivo nanotoxicity and safety testing of these nanotubes to evaluate their suitability in different fields.
原文英語
期刊Journal of Food and Drug Analysis
27
發行號1
DOIs
出版狀態接受/付印 - 一月 2019

Keywords

  • Application
  • Cyclic peptide
  • Nanotube

ASJC Scopus subject areas

  • 食品科學
  • 藥理

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