TY - JOUR
T1 - Application of fluid-attenuated inversion recovery pulse sequence in children with tuberous sclerosis
AU - Chien, Jerry Chin Wei
AU - Peng, Steven Shinn Forng
AU - Liu, Hon Man
AU - Huang, Kou Mou
AU - Li, Yiu Wah
PY - 1999/11
Y1 - 1999/11
N2 - To evaluate the application of Fluid-Attenuated Inversion Recovery (FLAIR) pulse sequence to increase the sensitivity of detecting tubers in tuberous sclerosis patients compared with fast spin-echo T2-weighted (FSET2W) image, we obtained 12 magnetic resonance (MR) images in 10 patients (mean age = 57.7 months old). Among the 12 examinations, 114 cortical and 128 subcortical tubers were revealed on the FLAIR images, whereas 54 and 72 tubers were found respectively on the FSET2W images. This may be due to the FLAIR pulse sequences remarkably attenuated CSF signals in comparison with the FSET2W images. However, FSET2W image delineated more subependymal nodules than FLAIR imaging did. Gd-DTPA enhanced T/W image is the most suitable pulse sequence to detect giant cell astrocytoma near the foramen of Monro. The results in cases of infants and little children were similar.
AB - To evaluate the application of Fluid-Attenuated Inversion Recovery (FLAIR) pulse sequence to increase the sensitivity of detecting tubers in tuberous sclerosis patients compared with fast spin-echo T2-weighted (FSET2W) image, we obtained 12 magnetic resonance (MR) images in 10 patients (mean age = 57.7 months old). Among the 12 examinations, 114 cortical and 128 subcortical tubers were revealed on the FLAIR images, whereas 54 and 72 tubers were found respectively on the FSET2W images. This may be due to the FLAIR pulse sequences remarkably attenuated CSF signals in comparison with the FSET2W images. However, FSET2W image delineated more subependymal nodules than FLAIR imaging did. Gd-DTPA enhanced T/W image is the most suitable pulse sequence to detect giant cell astrocytoma near the foramen of Monro. The results in cases of infants and little children were similar.
KW - Flluid-attenuated inversion recovery
KW - Pulse sequence
KW - Tuberous sclerosis
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M3 - Article
C2 - 10927952
AN - SCOPUS:0033491567
VL - 40
SP - 393
EP - 399
JO - Acta Paediatrica Sinica
JF - Acta Paediatrica Sinica
SN - 1875-9572
IS - 6
ER -