Apoptosis occurs more frequently in intraductal carcinoma than in infiltrating duct carcinoma of human breast cancer and correlates with altered p53 expression: Detected by terminal-deoxynucleotidyl-transferase- mediated dUTP-FITC nick end labelling (TUNEL)

H. J. Harn, K. L. Shen, K. C. Yueh, L. I. Ho, J. C. Yu, S. C. Chiu, W. H. Lee

研究成果: 雜誌貢獻文章同行評審

28 引文 斯高帕斯(Scopus)

摘要

Aims: We examined the relationship between apoptosis and three different major stages of human breast carcinoma: intraductal carcinoma (DCIS), infiltrating duct carcinoma (IDC) and metastatic carcinoma in lymph nodes. We also determined the correlation between apoptosis and oestrogen receptor (ER), progesterone receptor (PR) and p53. Methods and results: The study investigates the extent of apoptosis in 63 breast carcinomas by in-situ endlabelling, in formalin-fixed, paraffin-processed tissue sections. The 63 breast carcinomas, included 22 DCISs, 26 IDCs, three infiltrating lobular carcinomas (ILC) and 12 metastatic lymph nodes. The apoptotic labelling index was higher in DCIS than IDC and metastatic carcinoma (P

原文英語
頁(從 - 到)534-539
頁數6
期刊Histopathology
31
發行號6
出版狀態已發佈 - 1997
對外發佈Yes

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Cell Biology

指紋 深入研究「Apoptosis occurs more frequently in intraductal carcinoma than in infiltrating duct carcinoma of human breast cancer and correlates with altered p53 expression: Detected by terminal-deoxynucleotidyl-transferase- mediated dUTP-FITC nick end labelling (TUNEL)」主題。共同形成了獨特的指紋。

引用此