Apoptosis in nasopharyngeal carcinoma as related to histopathological characteristics and clinical stage

H. J. Harn, H. F. Hsieh, L. I. Ho, C. P. Yu, J. H. Chen, C. C. Chiu, H. C. Fan, W. H. Lee

研究成果: 雜誌貢獻文章同行評審

18 引文 斯高帕斯(Scopus)

摘要

Aims: We investigated the significance of apoptosis, using the terminal deoxynucleotidyl transferase mediated dUTP-digoxigenin nick end-labelling method, in nasopharyngeal carcinoma biopsy samples. Methods and results: The apoptotic index (AI) in 50 nasopharyngeal carcinomas was compared with various histopathological features and clinical stage. Also, the AI was correlated with p53, bcl-2 and Ki67 expression by immunohistochemistry. In histopathological studies, the AI was significantly higher in mixed cellular type (MC) than in keratizing squamous cell type (KS) and spindle cell type (SC) (P

原文英語
頁(從 - 到)117-122
頁數6
期刊Histopathology
33
發行號2
DOIs
出版狀態已發佈 - 1998
對外發佈

ASJC Scopus subject areas

  • 解剖學
  • 病理學與法醫學
  • 細胞生物學

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