Apical segmental dysfunction is an unusual finding in hypertrophic cardiomyopathy (HCM). It is characterized by a poor clinical course and a high incidence of malignant ventricular tachyarrhythmias. Long-term prognosis of patients with HCM and apical segmental dysfunction is still unclear. We report 2 cases of apical segmental dysfunction in HCM in whom progressive apical dilatation and congestive heart failure developed. Both patients died suddenly, and intractable ventricular tachyarrhythmias were documented in 1 case during resuscitation. This report provides further evidence that apical segmental dysfunction might predict a subgroup of patients with HCM who are likely to develop end-stage heart failure and are at high risk of sudden cardiac death.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Pharmacology (medical)
Ko, Y. L., Lin, J. L., Lei, M. I., Chen, J. J., Tsou, S. S., Kuan, P., & Lien, W. P. (1995). Apical segmental dysfunction in hypertrophic cardiomyopathy: Progression into end-stage heart failure with sudden cardiac death. Cardiology (Switzerland), 86(5), 436-440. https://doi.org/10.1159/000176917