Antioxidant activity of some plant extracts towards xanthine oxidase, lipoxygenase and tyrosinase

Chin Hui Chen, Hsiu Chen Chan, Yi Tsu Chu, Hsin Yi Ho, Pi Yu Chen, Zong-Huei Li, Ching Kuo Lee

研究成果: 雜誌貢獻文章同行評審

75 引文 斯高帕斯(Scopus)

摘要

Natural products have the potential to be developed into new drugs for the treatment of various diseases. The aim of the present study was to screen the antioxidant activities of some common edible fruits, garden plants and medicinal plants indigenous to Taiwan. This was performed by assessing the activities of lipoxygenase, xanthine oxidase and tyrosinase following incubation with extracts from these plants. A further aim was touse HPLC-DAD and tyrosinase to chromatographically identify the antioxidative constituents obtained from an extract exhibiting strong antioxidative properties. The acetone extracts of 27 cultivated plant species from Taiwan were tested for antioxidant activities towards xanthine oxidase, tyrosinase and lipoxygenase using spectrophotometric assays. Koelreuteria henryi, Prunus campanulata, and Rhodiola rosea showed the highest xanthine oxidase inhibitory activities. Camellia sinensis, Rhodiola rosea, and Koelreuteria henryi exhibited good tyrosinase inhibitory activities and potent anti-lipoxygenase activities. As Koelreuteria henryi had notable significant inhibitory activities towards xanthine oxidase, tyrosinase, and lipoxygenase, it was further tested with tyrosinase and HPLC-DAD. The results from this part of the study revealed that the more powerful the antioxidant capability of the extracted component, the greater the decrease in peak height obtained after reacting with tyrosinase. Additional studies are warranted to further characterize the compounds responsible for the antioxidant properties of the examined extracts.

原文英語
頁(從 - 到)2947-2958
頁數12
期刊Molecules
14
發行號8
DOIs
出版狀態已發佈 - 八月 2009

ASJC Scopus subject areas

  • 有機化學

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