Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats

Kunio Suetsuna, Keisei Maekawa, Jiun Rong Chen

研究成果: 雜誌貢獻文章

149 引文 斯高帕斯(Scopus)

摘要

We examined the angiotensin I-converting enzyme (ACE) inhibitory activity and antihypertensive effect of the hot water extract of wakame, Undaria pinnatifida. Ten dipeptides were isolated from the extract by several steps of chromatography, and their amino acid sequences were Tyr-His, Lys-Trp, Lys-Tyr, Lys-Phe, Phe-Tyr, Val-Trp, Val-Phe, Ile-Tyr, Ile-Trp, and Val-Tyr. Both single administration and repeated oral administration of synthetic Tyr-His, Lys-Tyr, Phe-Tyr, and Ile-Tyr significantly decreased blood pressure in spontaneously hypertensive rats.

原文英語
頁(從 - 到)267-272
頁數6
期刊Journal of Nutritional Biochemistry
15
發行號5
DOIs
出版狀態已發佈 - 五月 2004

    指紋

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

引用此