TY - JOUR
T1 - Antidiabetic dimeric guianolides and a lignan glycoside from Lactuca indica
AU - Hou, Chia Chung
AU - Lin, Shwu Jiuan
AU - Cheng, Juei Tang
AU - Hsu, Feng-Lin
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Three novel sesquiterpene lactones, lactucain A (1), B (2), and C (3), and a new furofuran lignan, lactucaside (4), were isolated from Lactuca indica along with nine known compounds, 11β,13-dihydrolactucin, cichoriosides B, quercetin, quercetin 3-O-glucoside, rutin, apigenin, luteolin, luteolin 7-O-glucuronide, and chlorogenic acid. Among these compounds, latucain C (3) and lactucaside (4) showed significant antidiabetic activity.
AB - Three novel sesquiterpene lactones, lactucain A (1), B (2), and C (3), and a new furofuran lignan, lactucaside (4), were isolated from Lactuca indica along with nine known compounds, 11β,13-dihydrolactucin, cichoriosides B, quercetin, quercetin 3-O-glucoside, rutin, apigenin, luteolin, luteolin 7-O-glucuronide, and chlorogenic acid. Among these compounds, latucain C (3) and lactucaside (4) showed significant antidiabetic activity.
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U2 - 10.1021/np0205349
DO - 10.1021/np0205349
M3 - Article
C2 - 12762795
AN - SCOPUS:0037850972
VL - 66
SP - 625
EP - 629
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0163-3864
IS - 5
ER -