Analysis of cell ratio and drug concentration influence in feigning lung cancer model

Kuo Wei Chang, Tse Shao Chen, Shilpa Sivashankar, Ming Yan Chen, Kang Yun Lee, Cheng Hsien Liu

研究成果: 書貢獻/報告類型會議貢獻

1 引文 斯高帕斯(Scopus)

摘要

Here presented is an integrated drug testing system based on a mimetic lung tissue pattern of in vitro targeted therapy testing. The integrated targeted therapy testing system consists of continuous concentration gradient platform and dielectrophoretic (DEP) cell patterning chambers. DEP forces are based on polarity difference to manipulate heterogeneous cells for mimicking the inherent lung morphology and increasing the cell-cell interaction. The multiplexed microchannels allow for simultaneous administration of multiple drug doses to functional lung cancer cells while an incorporated concentration gradient enables the in vitro dose-dependent drug responses to predict in vivo hepatotoxicity.

原文英語
主出版物標題2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
頁面369-372
頁數4
DOIs
出版狀態已發佈 - 2013
對外發佈
事件2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, 西班牙
持續時間: 六月 16 2013六月 20 2013

其他

其他2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
國家/地區西班牙
城市Barcelona
期間6/16/136/20/13

ASJC Scopus subject areas

  • 硬體和架構
  • 電氣與電子工程

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