An overview of the rare parotid gland cancer

Kimberley Ho, Helen Lin, David K. Ann, Peiguo G. Chu, Yun Yen

研究成果: 雜誌貢獻回顧型文獻同行評審

37 引文 斯高帕斯(Scopus)

摘要

Cancer of the parotid gland is relatively rare, but carries poor prognosis owing to its prevailing distant metastases. In addition to the disease's basic epidemiology and pathology, we review some current discoveries of its tumorigenesis molecular mechanism. Based on published salivary gland cancer clinical trial data, non-surgical antitumor efficacies amongst a range of chemotherapy, radiation, and concurrent therapy regimens are compared. We also present the current development status of novel radiation therapy and targeted therapeutics, focusing on intensity-modulated radiation therapy (IMRT), and epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) blockages, which are showing promise for improving parotid gland cancer management.

原文英語
文章編號40
期刊Head and Neck Oncology
3
發行號1
DOIs
出版狀態已發佈 - 九月 21 2011
對外發佈Yes

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Oncology

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