An environmental friendly tapioca starch-alginate cultured scaffold as biomimetic muscle tissue

Che Wei Lin, Po Ting Wu, Kuan Ting Liu, Yu Jui Fan, Jiashing Yu

研究成果: 雜誌貢獻文章同行評審

摘要

Natural porous scaffolds have been studied and developed for decades in biomedical science in order to support cells with a simulated extracellular matrix in natural tissue as an ideal environment. Such three-dimensional scaffolds provide many degrees of freedom to modulate cell activity, such as porosity, pore size, mechanical strength, biodegradability, and biocompatibility. In this study, a porous, three-dimensional material of alginate incorporating tapioca starch was fabricated. A particular freeze-gelation method was applied to homogenously mix starch in the alginate, and the concentration was controllable. This pure natural composite porous scaffold was characterized physically and biologically. The synergistic functions, including biocompatibility, biodegradability, cell adhesion, and cell proliferation, were also investigated. A myogenic differentiation model further verified that the composite porous scaffold provided a suitable environment, supporting the differentiation effect in the myogenic process. The positive results demonstrated that this novel material has the potential to serve as a biomedical or clean meat appliance.

原文英語
文章編號2882
期刊Polymers
13
發行號17
DOIs
出版狀態已發佈 - 九月 1 2021

ASJC Scopus subject areas

  • 化學 (全部)
  • 聚合物和塑料

指紋

深入研究「An environmental friendly tapioca starch-alginate cultured scaffold as biomimetic muscle tissue」主題。共同形成了獨特的指紋。

引用此