Acute respiratory distress syndrome following intrathecal methotrexate administration: A case report and review of literature

M. S. Dai, C. L. Ho, Y. C. Chen, W. Y. Kao, T. Y. Chao

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16 引文 斯高帕斯(Scopus)

摘要

Acute Respiratory distress syndrome (ARDS) is a rare complication following intrathecal (IT) injection of methotrexate (MTX) in adult acute lymphoblastic leukemia (ALL) patients. A 19-year-old man with ALL developed strikingly acute respiratory failure during central nervous system (CNS) prophylaxis with IT MTX administration and cranial irradiation. Histopathologic study of the lungs revealed a pattern of diffuse alveolar damage with interstitial cellular infiltration. His symptoms were relieved soon following treatment with corticosteroids and the pulmonary infiltrates resolved gradually. Pulmonary symptoms did not recur as he was continuously treated with oral corticosteroids.

原文英語
頁(從 - 到)696-699
頁數4
期刊Annals of Hematology
79
發行號12
DOIs
出版狀態已發佈 - 2000
對外發佈Yes

ASJC Scopus subject areas

  • Hematology

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