Acute renal failure induced by bentazone: 2 case reports and a comprehensive review

I. Wen Wu, Mai Szu Wu, Ja Liang Lin

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

摘要

Bentazone is a herbicide widely used in the agrochemical field and acts by interference in photosynthesis in plants. Case reports of bentazone poisoning in humans are rare, but hepatorenal damage and death have been described, though the mechanism of toxicity remains speculative. We describe 2 cases of acute bentazone poisoning and compare these with other literature reports. The clinical picture included nausea, vomiting, diarrhea, abdominal pain with gastrointestinal corrosive injury, dyspnea and acute hepatorenal dysfunction. Respiratory failure, acute hepatitis, acute renal failure requiring hemodialysis, and death occurred following a large ingested dose of 1,764 mg/kg. Bentazone may have direct organ toxicity, especially in liver and kidney, in subjects with renal hypoperfusion, rhabdomyolysis, preexisting renal disease or concomitant nephrotoxic drug consumption. Aggressive supportive therapy, hydration and measures to prevent renal hypoperfusion are essential to reverse acute renal failure.

原文英語
頁(從 - 到)256-260
頁數5
期刊Journal of Nephrology
21
發行號2
出版狀態已發佈 - 三月 2008
對外發佈Yes

ASJC Scopus subject areas

  • Nephrology

指紋 深入研究「Acute renal failure induced by bentazone: 2 case reports and a comprehensive review」主題。共同形成了獨特的指紋。

  • 引用此