Acute effects of ephedra on autonomic nervous modulation in healthy young adults

Wei-Lung Chen, T. H. Tsai, C. C H Yang, T. B J Kuo

研究成果: 雜誌貢獻文章同行評審

10 引文 斯高帕斯(Scopus)

摘要

The aim of this study was to assess the acute effects of ephedra on autonomic nervous modulation by means of heart rate variability (HRV) analysis, using a randomized, double-blind, placebo-controlled, crossover design. On three separate days, 20 healthy subjects took capsules containing either 1 or 2 g of ephedra dry extract or a placebo, and the sequential percentage changes in HRV measures were compared. After the subjects took ephedra, the normalized low-frequency component (LF) and the ratio of LF to high-frequency component (HF) increased significantly in a dose-dependent manner, whereas the normalized HF (HF%) decreased significantly. We conclude that ingestion of ephedra tilts the sympathovagal balance dose-dependently toward increased sympathetic activity and impairs parasympathetic activity.
原文英語
頁(從 - 到)39-44
頁數6
期刊Clinical Pharmacology and Therapeutics
88
發行號1
DOIs
出版狀態已發佈 - 七月 24 2010
對外發佈Yes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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