Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress

Tsai Kun Li, Allen Y. Chen, Chiang Yu, Yong Mao, Huimin Wang, Leroy-Fong Liu

研究成果: 雜誌貢獻文章

137 引文 斯高帕斯(Scopus)

摘要

Hydrogen peroxide (H 2O 2), a reactive oxygen species (ROS), is known to induce oxidative stress and apoptosis. U937 cells treated with H 2O 2 were shown to produce high molecular weight (HMW) DNA fragments ~50 to 100 kb in size in

原文英語
頁(從 - 到)1553-1560
頁數8
期刊Genes and Development
13
發行號12
出版狀態已發佈 - 六月 15 1999
對外發佈Yes

    指紋

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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