Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress

Tsai Kun Li; Allen Y. Chen; Chiang Yu; Yong Mao; Huimin Wang; Leroy-Fong Liu

Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress

Tsai Kun Li, Allen Y. Chen, Chiang Yu, Yong Mao, Huimin Wang, Leroy-Fong Liu

研究成果: 雜誌貢獻 › 文章

摘要

Hydrogen peroxide (H ₂O ₂), a reactive oxygen species (ROS), is known to induce oxidative stress and apoptosis. U937 cells treated with H ₂O ₂ were shown to produce high molecular weight (HMW) DNA fragments ~50 to 100 kb in size in

原文	英語
頁（從 - 到）	1553-1560
頁數	8
期刊	Genes and Development
卷	13
發行號	12
出版狀態	已發佈 - 六月 15 1999
對外發佈	Yes

ASJC Scopus subject areas

Genetics
Developmental Biology

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引用此

Li, T. K., Chen, A. Y., Yu, C., Mao, Y., Wang, H., & Liu, L-F. (1999). Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress. Genes and Development, 13(12), 1553-1560.

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