Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

Zong-Huei Li; Yu Chang Chen; Ching Kuo Lee; Hsun Shuo Chang; Ching Chuan Kuo; Che Yi Chao; Jing Jer Lin; Lee Chiang Lo; Yueh Hsiung Kuo

Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

Zong-Huei Li, Yu Chang Chen, Ching Kuo Lee, Hsun Shuo Chang, Ching Chuan Kuo, Che Yi Chao, Jing Jer Lin, Lee Chiang Lo, Yueh Hsiung Kuo

研究成果: 雜誌貢獻 › 文章 › 同行評審

6 引文斯高帕斯（Scopus）

摘要

Aconitum carmichaeli Debx. is a traditional Chinese medicine commonly employed for curing a wide array of diseases in East Asia. From the ethyl acetate soluble fraction of the methanolic extracts of A. carmichaeli, a new alkaloid, aconitamide (1), along with eighteen known compounds 2-19 were isolated by column chromatography and identified on the basis of spectroscopic analyses. The anti-telomerase activity of 1-19 was also assessed, but no activity was found, even at a concentration higher than 30 μM.

原文	英語
頁（從 - 到）	827-828
頁數	2
期刊	Natural Product Communications
卷	8
發行號	6
出版狀態	已發佈 - 2013

ASJC Scopus subject areas

藥物發現
藥理
補充和替代醫學
植物科學

其它文件與鏈接

引用此

@article{4319317093514a20a66c9a992d1b679a,

title = "Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli",

abstract = "Aconitum carmichaeli Debx. is a traditional Chinese medicine commonly employed for curing a wide array of diseases in East Asia. From the ethyl acetate soluble fraction of the methanolic extracts of A. carmichaeli, a new alkaloid, aconitamide (1), along with eighteen known compounds 2-19 were isolated by column chromatography and identified on the basis of spectroscopic analyses. The anti-telomerase activity of 1-19 was also assessed, but no activity was found, even at a concentration higher than 30 μM.",

keywords = "Aconitamide, Aconitum carmichaeli Debx., Anti-telomerase, Chinese herb, Ranunculaceae, Roots",

author = "Zong-Huei Li and Chen, {Yu Chang} and Lee, {Ching Kuo} and Chang, {Hsun Shuo} and Kuo, {Ching Chuan} and Chao, {Che Yi} and Lin, {Jing Jer} and Lo, {Lee Chiang} and Kuo, {Yueh Hsiung}",

year = "2013",

language = "English",

volume = "8",

pages = "827--828",

journal = "Natural Product Communications",

issn = "1934-578X",

publisher = "Natural Product Communications",

number = "6",

}

TY - JOUR

T1 - Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

AU - Li, Zong-Huei

AU - Chen, Yu Chang

AU - Lee, Ching Kuo

AU - Chang, Hsun Shuo

AU - Kuo, Ching Chuan

AU - Chao, Che Yi

AU - Lin, Jing Jer

AU - Lo, Lee Chiang

AU - Kuo, Yueh Hsiung

PY - 2013

Y1 - 2013

N2 - Aconitum carmichaeli Debx. is a traditional Chinese medicine commonly employed for curing a wide array of diseases in East Asia. From the ethyl acetate soluble fraction of the methanolic extracts of A. carmichaeli, a new alkaloid, aconitamide (1), along with eighteen known compounds 2-19 were isolated by column chromatography and identified on the basis of spectroscopic analyses. The anti-telomerase activity of 1-19 was also assessed, but no activity was found, even at a concentration higher than 30 μM.

AB - Aconitum carmichaeli Debx. is a traditional Chinese medicine commonly employed for curing a wide array of diseases in East Asia. From the ethyl acetate soluble fraction of the methanolic extracts of A. carmichaeli, a new alkaloid, aconitamide (1), along with eighteen known compounds 2-19 were isolated by column chromatography and identified on the basis of spectroscopic analyses. The anti-telomerase activity of 1-19 was also assessed, but no activity was found, even at a concentration higher than 30 μM.

KW - Aconitamide

KW - Aconitum carmichaeli Debx.

KW - Anti-telomerase

KW - Chinese herb

KW - Ranunculaceae

KW - Roots

UR - http://www.scopus.com/inward/record.url?scp=84886434523&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886434523&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84886434523

SN - 1934-578X

VL - 8

SP - 827

EP - 828

JO - Natural Product Communications

JF - Natural Product Communications

IS - 6

ER -

Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

摘要

ASJC Scopus subject areas

其它文件與鏈接

指紋

引用此