A viscosity and C-reactive protein sensing technique based on Brownian motion measurements by total-internal-reflective-fluorescent velocimetry

Yu Jui Fan, Yi Hsing Liu, Tzu Heng Wu, Horn Jiunn Sheen, Shiming Lin, Jing Fa Tsai

研究成果: 書貢獻/報告類型會議貢獻

摘要

In this study, a two-section clinical sample detection on viscosity and bimolecule sensing technique based on measuring the Brownian velocity of nanobeads has been successfully developed. Bare and antibody-coated fluorescent nanobeads were used to detect various viscous solutions and different concentrations of bio-molecular samples, respectively. The Brownian velocities of the nanobeads became slower when the sizes of antibody-coated nanobeads increased during the antibody-antigen interaction process or when the bare nanobeads were seeded in a higher viscosity solution. In order to obtain the characteristics of the Brownian motion of nanobeads in the static liquid, total internal reflection fluorescent velocimetry (TIRFV) was employed. This sensing technique should be useful in clinical diagnosis, bio-molecule judgment, and the study of fluid characteristics.
原文英語
主出版物標題IEEE Sensors 2010 Conference, SENSORS 2010
頁面395-400
頁數6
DOIs
出版狀態已發佈 - 2010
對外發佈
事件9th IEEE Sensors Conference 2010, SENSORS 2010 - Waikoloa, HI, 美国
持續時間: 十一月 1 2010十一月 4 2010

出版系列

名字Proceedings of IEEE Sensors

會議

會議9th IEEE Sensors Conference 2010, SENSORS 2010
國家/地區美国
城市Waikoloa, HI
期間11/1/1011/4/10

ASJC Scopus subject areas

  • 電氣與電子工程

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