A solitary congenital self-healing histiocytosis: Report of a case and review of the literature

Shya Wen Shy, Wei Hwa Lee, Yung Ching Chang, Wei Wu

研究成果: 雜誌貢獻文章同行評審

12 引文 斯高帕斯(Scopus)

摘要

Congenital self-healing histiocytosis (CSHH), and especially the solitary variant, is a rare primary skin disorder. We report on a newborn with a congenital solitary ulcerated skin nodule. Extracutaneous involvement was not found. A skin biopsy was performed at the age of 44 days and revealed a dense dermal infiltrate of large histiocytic cells. Immunohistochemical study revealed that the cells of the dermal infiltrate were Langerhans' cells which were strongly positive for S-100 and negative for lysozyme, leukocyte common antigen and alpha-1-antichymotrypsin. The skin lesion involuted spontaneously over the next month without any treatment. The clinical, histopathological and immunohistochemical results fulfilled the criteria of solitary CSHH. We herein report the first case of CSHH in Taiwan and the twelfth case of solitary CSHH in the world.

原文英語
頁(從 - 到)869-874
頁數6
期刊Pathology Research and Practice
192
發行號8
DOIs
出版狀態已發佈 - 1996

ASJC Scopus subject areas

  • 病理學與法醫學
  • 細胞生物學

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