A portable micro gas chromatography system for lung cancer associated volatile organic compound detection

Te Hsuen Tzeng, Chun Yen Kuo, San Yuan Wang, Po Kai Huang, Yen Ming Huang, Wei Che Hsieh, Yu Jie Huang, Po Hung Kuo, Shih An Yu, Si Chen Lee, Yufeng Jane Tseng, Wei Cheng Tian, Shey Shi Lu

研究成果: 雜誌貢獻文章同行評審

46 引文 斯高帕斯(Scopus)

摘要

With the help of micro-electromechanical systems (MEMS) and complementary metal-oxide-semiconductor (CMOS) technology, a portable micro gas chromatography (μGC) system for lung cancer associated volatile organic compounds (VOCs) detection is realized for the first time. The system is composed of an MEMS preconcentrator, an MEMS separation column, and a CMOS system-on-chip (SoC). The preconcentrator provides a concentration ratio of 2170. The separation column can separate more than seven types of lung cancer associated VOCs. The SoC is fabricated by a TSMC 0.35 μm 2P4M process including the CMOS VOCs detector, sensor calibration circuit, low-noise chopper instrumentation amplifier (IA), 10 bit analog to digital converter, and the microcontrol unit (MCU). Experimental results show that the system is able to detect seven types of lung cancer associated VOCs (acetone, 2-butanone, benzene, heptane, toluene, m-xylene, 1,3,5-trimethylbenzene). The concentration linearity is R2 = 0.985 and the detection sensitivity is up to 15 ppb with 1,3,5-trimethylbenzene.
原文英語
文章編號7314865
頁(從 - 到)259-272
頁數14
期刊IEEE Journal of Solid-State Circuits
51
發行號1
DOIs
出版狀態已發佈 - 一月 1 2016
對外發佈

ASJC Scopus subject areas

  • 電氣與電子工程

指紋

深入研究「A portable micro gas chromatography system for lung cancer associated volatile organic compound detection」主題。共同形成了獨特的指紋。

引用此