A population-based epidemiological study of human T-cell leukemia virus type I infection in Kin-Hu, Kinmen

Yi Ming A. Chen, Hui Ching Lin, Pesus Chou

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

摘要

Kinmen is a group of small islands located between Taiwan and Fu-Kien Province of mainland China. The general population in Kinmen are descendants of immigrants from mainland China who began arriving around 317 A.D. Since it has been reported that 0.48% of adults in Taiwan have HTLV-I infection, the decision was made to conduct a community-based epidemiological study in Kinmen to understand the origin and dissemination of HTLV-I in north-east Asia. Over 68% of residents of Kin-Hu township in Kinmen over 30 years of age participated in this study. Eight of 1,425 males and 14 of 1,595 females had HTLV-I infection. Antibody reactivities were further tested by Western blot assays with HTLV-I or HTLV-II type-specific recombinant envelope glycoproteins, and it was determined that all of those infected had HTLV-I and none had HTLV-II. Logistic regression was used for multivariate analysis. The final model indicated that the significant factors associated with HTLV-I infection in Kinmen were age and coastal residency. Age was positively correlated with HTLV-I infection. The eastern coastal area had a rate of HTLV-I infection 3.1 times higher than other areas in Kin-Hu. Further genetic analysis in Kinmen is needed to elucidate a relationship with other HTLV-I isolates in the world.
原文英語
頁(從 - 到)569-573
頁數5
期刊International Journal of Cancer
65
發行號5
DOIs
出版狀態已發佈 - 三月 1 1996
對外發佈Yes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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