A novel strategy by using synovial membranes, cartilage fragments and mesenchymal stem cells for cartilage tissue engineering: A novel strategy for cartilage tissue engineering

Chia Chun Chen, Jia Si Hu, Hsu Wei Fang, Chih Hung Chang

研究成果: 書貢獻/報告類型會議貢獻

1 引文 斯高帕斯(Scopus)

摘要

In this study, we used cartilage fragments, synovial membranes and bone marrow-derived mesenchymal stem cells to mimic a knee joint environment for cartilage tissue engineering. SEM images showed that MSCs attached and grew well in the constructs and exhibited polygonal cell morphologies. Histological analyses revealed that the constructs showed round cell appearances with positive Alcian blue staining. After 28 days of in-vitro culture, the gene expressions of type II collagen were significantly increased. Therefore, we suggested that the constructs containing cartilage fragments, synovial membranes and MSCs resulted in better outcomes for chondrogenesis. This might be a novel strategy for articular cartilage repair and regeneration.
原文英語
主出版物標題Proceedings - 2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012
頁面965-967
頁數3
DOIs
出版狀態已發佈 - 十月 1 2012
對外發佈
事件2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012 - Macau, 中国
持續時間: 五月 28 2012五月 30 2012

出版系列

名字Proceedings - 2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012

會議

會議2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012
國家/地區中国
城市Macau
期間5/28/125/30/12

ASJC Scopus subject areas

  • 生物技術
  • 生物醫學工程

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