A new class of biocompatible tricalcium phosphate/ polypropylene carbonate/ polylactic acid nanocomposites with controlled flexibility and biodegradability

Ta I. Yang, Po Liang Lin, Guang Wei Chang, Yu Chen Tseng, Zhe Yang Yu, Charng Bin Yang, Guo Chung Dong, Hsu Wei Fang

研究成果: 雜誌貢獻文章同行評審

2 引文 斯高帕斯(Scopus)

摘要

The goal of this research is to improve the mechanical and biological properties of widely used polylactic acid (PLA) in order to enhance the mechanical processability and bioactivity performance of the PLA-based medical implants. A polypropylene carbonate (PPC) polymer was utilized to control the bending strength of the PLA composites, leading to elastic PLA composites without any nontoxicity to osteoblast-like cells. Furthermore, a bioceramic material, tricalcium phosphate (β-TCP), was also introduced to further finetune the mechanical properties of the PLA composites. Experimental data revealed that the resulting elastic β-TCP/PPC/PLA nanocomposites exhibited elongation at break (%) of 1100% with tensile strength close to 1 MPa. The method developed in this study provides a simple strategy for fabricating biodegradable PLA based-materials with desired mechanical processability and malleability at room temperature.
原文英語
頁(從 - 到)194-199
頁數6
期刊Current Nanoscience
10
發行號2
DOIs
出版狀態已發佈 - 一月 1 2014
對外發佈

ASJC Scopus subject areas

  • 生物技術
  • 生物工程
  • 生物醫學工程
  • 醫藥(雜項)
  • 藥學科學

指紋

深入研究「A new class of biocompatible tricalcium phosphate/ polypropylene carbonate/ polylactic acid nanocomposites with controlled flexibility and biodegradability」主題。共同形成了獨特的指紋。

引用此