A new capnellene skeleton from the octocoral Capnella imbricata (Quoy & Gaimard, 1833)

I. Ting Wu, Yu Chen Fan, Guan Zhou Lin, Yi Lin Wang, Tsong Long Hwang, Kuei Hung Lai, Hsu Ming Chung

研究成果: 雜誌貢獻文章同行評審

摘要

Chemical investigations on the ethyl acetate extract of the octocoral Capnella imbricata collected from the waters of Taiwan, which led to the isolation of three capnellenes (1–3), including one new metabolite, △9(12)-capnellene-8β,10α,15-triol (1), along with two known metabolites, △9(12)-capnellene-5α,8β,10α-triol (2), and △9(12)-capnellene-8β,10α-diol (3). The structures of the isolated metabolites were elucidated through extensive spectroscopic analyses, while the relative stereochemistry of 3 was confirmed by a single-crystal X-ray diffraction analysis for the first time in this study. Compounds 1–3 were evaluated in terms of their anti-inflammatory activity by examining their inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils.
原文英語
文章編號133995
期刊Journal of Molecular Structure
1271
DOIs
出版狀態已發佈 - 1月 2023

ASJC Scopus subject areas

  • 分析化學
  • 光譜
  • 有機化學
  • 無機化學

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