@article{f684d072c4354e9ebc5e0ea56537cce5,
title = "A new angular naphthopyrone from feather star Comanthus parvicirrus (M{\"u}ller, 1841)",
abstract = "A chemical investigation was carried out on a feather star Comanthus parvicirrus collected from the waters of Southern Taiwan, which led to the isolation of three angular naphthopyrones (1–3), including one new metabolite, 8‑hydroxy-5,6,9,10-tetramethoxy-2-methyl-4H-benzo[h]chromen-4-one (1). The structures of compounds 1–3 were assigned based on spectroscopic methods, including UV, MS, 1D- and 2D-NMR spectra, and the structure of 1 was established by single-crystal X-ray diffraction analysis directly. The compound 3 were found to exhibit significant anti-inflammatory activity in lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophages through attenuating the expression of the inducible nitric oxide synthase (iNOS) proteins.",
keywords = "Comanthus parvicirrus, Crinoid, Feather star, iNOS, Naphthopyrone, X-ray",
author = "Ke, {Zong You} and Chen, {Jun Wen} and Wu, {Bo Yan} and Jhan, {Yi Yan} and Wen, {Zhi Hong} and Kung, {Te An} and Sung, {Ping Jyun} and Chen, {Jih Jung} and Lai, {Kuei Hung} and Chung, {Hsu Ming}",
note = "Funding Information: This research was supported by the grants from the National Pingtung University and the Ministry of Science and Technology, Taiwan (Grant Nos: MOST 110-2320-B-153-001) awarded to Hsu-Ming Chung; by the grant from the Ministry of Science and Technology (MOST 110-2320-B-038-034), Ministry of Education (DP2-110-21121-01-N-12-03), and Taipei Medical University (TMU109-AE1-B15) awarded to Kuei-Hung Lai. The authors are thankful the High Valued Instrument Center, National Sun Yat-sen University, for the mass (MS000600) and NMR (NMR001100) Spectra (MOST 110-2731-M-110-001); and to the Instrumentation Center, National Taiwan University for providing X-ray facilities (MOST 110–2731-M-002–001, XRD000200). Funding Information: This research was supported by the grants from the National Pingtung University and the Ministry of Science and Technology, Taiwan (Grant Nos: MOST 110-2320-B-153-001) awarded to Hsu-Ming Chung; by the grant from the Ministry of Science and Technology (MOST 110-2320-B-038-034), Ministry of Education (DP2-110-21121-01-N-12-03), and Taipei Medical University (TMU109-AE1-B15) awarded to Kuei-Hung Lai. The authors are thankful the High Valued Instrument Center, National Sun Yat-sen University, for the mass (MS000600) and NMR (NMR001100) Spectra (MOST 110-2731-M-110-001); and to the Instrumentation Center, National Taiwan University for providing X-ray facilities (MOST 110?2731-M-002?001, XRD000200). Publisher Copyright: {\textcopyright} 2021 The Author(s)",
year = "2022",
month = apr,
day = "5",
doi = "10.1016/j.molstruc.2021.132261",
language = "English",
volume = "1253",
journal = "Journal of Molecular Structure",
issn = "0022-2860",
publisher = "Elsevier",
}