摘要
原文 | 英語 |
---|---|
期刊 | International Journal of Environmental Research and Public Health |
卷 | 16 |
發行號 | 2 |
DOIs | |
出版狀態 | 已發佈 - 一月 9 2019 |
指紋
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Health, Toxicology and Mutagenesis
引用此文
A Cross-Sectional Study of Endogenous Antioxidants and Patterns of Dental Visits of Periodontitis Patients. / Lee, Chang Yu; Choy, Cheuk Sing; Lai, Yu Cheng; Chang, Chao Chien; Teng, Nai Chia; Huang, Wan Ting; Lin, Che Tong; Huang, Yung Kai.
於: International Journal of Environmental Research and Public Health, 卷 16, 編號 2, 09.01.2019.研究成果: 雜誌貢獻 › 文章
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TY - JOUR
T1 - A Cross-Sectional Study of Endogenous Antioxidants and Patterns of Dental Visits of Periodontitis Patients
AU - Lee, Chang Yu
AU - Choy, Cheuk Sing
AU - Lai, Yu Cheng
AU - Chang, Chao Chien
AU - Teng, Nai Chia
AU - Huang, Wan Ting
AU - Lin, Che Tong
AU - Huang, Yung Kai
PY - 2019/1/9
Y1 - 2019/1/9
N2 - Periodontitis is an inflammatory disease, wherein endogenous antioxidants help to balance the inflammatory status. Oral health behaviors are related to the periodontal disease status. The aim of this study was to explore the associations between oral health behaviors and endogenous antioxidants in periodontitis patients. In total, 225 subjects diagnosed with periodontitis were enrolled in the study. Information obtained from the initial interview included socioeconomic and demographic characteristics, lifestyle factors, and oral health-related behaviors. The clinical periodontal parameters evaluated included bleeding on probing (BOP), the plaque index (PI), and probing depth (PD). Stimulated saliva was collected before periodontal therapy to determine five endogenous antioxidants (copper-zinc superoxide dismutase (Cu/Zn SOD), manganese SOD (MnSOD), thioredoxin 1 (Trx1), peroxiredoxin 2 (Prx2), and catalase (CAT)). When these five factors were adjusted for in patients whose last previous dental visit was >1 year, the patients' PI, BOP, and PD showed significant decreases because of an elevation in the Cu/Zn SOD level. Associations of endogenous antioxidants with levels of clinical periodontal parameters were much higher in subjects whose last previous dental visit was >1 year, compared to subjects whose last previous dental visit was <1 year. This study provides a better understanding of dental visit patterns and the salivary endogenous antioxidants that may underlie the symptomatic development of preclinical periodontitis.
AB - Periodontitis is an inflammatory disease, wherein endogenous antioxidants help to balance the inflammatory status. Oral health behaviors are related to the periodontal disease status. The aim of this study was to explore the associations between oral health behaviors and endogenous antioxidants in periodontitis patients. In total, 225 subjects diagnosed with periodontitis were enrolled in the study. Information obtained from the initial interview included socioeconomic and demographic characteristics, lifestyle factors, and oral health-related behaviors. The clinical periodontal parameters evaluated included bleeding on probing (BOP), the plaque index (PI), and probing depth (PD). Stimulated saliva was collected before periodontal therapy to determine five endogenous antioxidants (copper-zinc superoxide dismutase (Cu/Zn SOD), manganese SOD (MnSOD), thioredoxin 1 (Trx1), peroxiredoxin 2 (Prx2), and catalase (CAT)). When these five factors were adjusted for in patients whose last previous dental visit was >1 year, the patients' PI, BOP, and PD showed significant decreases because of an elevation in the Cu/Zn SOD level. Associations of endogenous antioxidants with levels of clinical periodontal parameters were much higher in subjects whose last previous dental visit was >1 year, compared to subjects whose last previous dental visit was <1 year. This study provides a better understanding of dental visit patterns and the salivary endogenous antioxidants that may underlie the symptomatic development of preclinical periodontitis.
KW - dental visit
KW - oxidative stress response
KW - periodontitis
KW - prevention
KW - salivary biomarker
UR - http://www.scopus.com/inward/record.url?scp=85059888298&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85059888298&partnerID=8YFLogxK
U2 - 10.3390/ijerph16020180
DO - 10.3390/ijerph16020180
M3 - Article
C2 - 30634539
AN - SCOPUS:85059888298
VL - 16
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
SN - 1661-7827
IS - 2
ER -