A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: A randomized, physician-blinded, split-face comparative trial

Chia Chen Wang, Yuh Mou Sue, Chih Hsiung Yang, Chih Kang Chen

研究成果: 雜誌貢獻文章

84 引文 斯高帕斯(Scopus)


Background: Q-switched (QS) pigmented lasers and intense pulsed light (IPL) successfully treat pigment disorders. Objective: We sought to compare efficacy and side effects of QS alexandrite laser (QSAL) and IPL for freckle and lentigo treatment in Asians. Methods: In all, 15 patients with freckles and 17 patients with lentigines were treated randomly with one session QSAL in one cheek and two sessions IPL in the other cheek at 4-week intervals. Efficacy was determined using a new pigmentation area and severity index score. Results: All patients experienced improvement (P <.0001). Postinflammatory hyperpigmentation developed in one patient with freckles and 8 patients with lentigines after QSAL. No postinflammatory hyperpigmentation occurred after IPL. Freckles achieved greater improvement after QSAL than IPL (P = .04). In lentigines, the results after IPL were better than QSAL among those with postinflammatory hyperpigmentation after QSAL. Limitations: Limitations include a small case number and short follow-up period. Conclusion: QSAL was superior to IPL for freckle treatment. IPL should be used for lentigines in Asian persons.

頁(從 - 到)804-810
期刊Journal of the American Academy of Dermatology
出版狀態已發佈 - 五月 2006


ASJC Scopus subject areas

  • Dermatology