A 10-year follow-up of triple-negative breast cancer patients in Taiwan

Che Lin, Su Yu Chien, Shou Jen Kuo, Li Sheng Chen, Shou Tung Chen, Hung Wen Lai, Tsai Wang Chang, Dar Ren Chen

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

Objective: This study aimed to investigate whether triple-negative breast cancer has a worse prognosis; here, we present the 10-year follow-up results of triple-negative breast cancer patients in Taiwan. Methods: We identified 2858 breast cancer patients in Taiwan, of whom 416 (14.6%) had triple-negative breast cancer. Data used for analysis were derived from those breast cancer patients who were diagnosed between January 1996 and December 2006. Results: In the Kaplan-Meier analysis, tumor subgroup (triple-negative breast cancer vs. non-triple-negative breast cancer) was a prognostic factor related to 10-year breast cancer death-specific survival and disease-free survival. The results of univariate analysis showed that tumor subgroup was a significant factor related to 10-year disease-free survival and breast cancer death-specific survival, as well as menopausal status, tumor size, lymph node, metastasis, grade, stage, estrogen receptor status, progesterone receptor status and her2/neu gene expression status. Similarly, the multivariate analysis also revealed that tumor subgroup was a significant factor related to 10-year breast cancer death-specific survival and disease-free survival, in addition to tumor size, lymph node, metastasis and grade. Conclusions: It was suggested that triple-negative breast cancer patients in Taiwan have worse 10-year survival. Notably, in node-positive patients, triple-negative breast cancer played a prognostic role in 10-year breast cancer death-specific survival.
原文英語
文章編號hyr196
頁(從 - 到)161-167
頁數7
期刊Japanese Journal of Clinical Oncology
42
發行號3
DOIs
出版狀態已發佈 - 三月 2012

指紋

Triple Negative Breast Neoplasms
Taiwan
Breast Neoplasms
Survival
Disease-Free Survival
Neoplasms
Lymph Nodes
Neoplasm Metastasis
erbB-2 Genes
Kaplan-Meier Estimate
Progesterone Receptors
Estrogen Receptors
Multivariate Analysis
Gene Expression

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Radiology Nuclear Medicine and imaging

引用此文

Lin, C., Chien, S. Y., Kuo, S. J., Chen, L. S., Chen, S. T., Lai, H. W., ... Chen, D. R. (2012). A 10-year follow-up of triple-negative breast cancer patients in Taiwan. Japanese Journal of Clinical Oncology, 42(3), 161-167. [hyr196]. https://doi.org/10.1093/jjco/hyr196

A 10-year follow-up of triple-negative breast cancer patients in Taiwan. / Lin, Che; Chien, Su Yu; Kuo, Shou Jen; Chen, Li Sheng; Chen, Shou Tung; Lai, Hung Wen; Chang, Tsai Wang; Chen, Dar Ren.

於: Japanese Journal of Clinical Oncology, 卷 42, 編號 3, hyr196, 03.2012, p. 161-167.

研究成果: 雜誌貢獻文章

Lin, C, Chien, SY, Kuo, SJ, Chen, LS, Chen, ST, Lai, HW, Chang, TW & Chen, DR 2012, 'A 10-year follow-up of triple-negative breast cancer patients in Taiwan', Japanese Journal of Clinical Oncology, 卷 42, 編號 3, hyr196, 頁 161-167. https://doi.org/10.1093/jjco/hyr196
Lin, Che ; Chien, Su Yu ; Kuo, Shou Jen ; Chen, Li Sheng ; Chen, Shou Tung ; Lai, Hung Wen ; Chang, Tsai Wang ; Chen, Dar Ren. / A 10-year follow-up of triple-negative breast cancer patients in Taiwan. 於: Japanese Journal of Clinical Oncology. 2012 ; 卷 42, 編號 3. 頁 161-167.
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