A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia

Kea Tiong Tang, Shih Wen Chiu, Chung-Hung Shih, Chia Ling Chang, Chia Min Yang, Da Jeng Yao, Jen Huo Wang, Chien Ming Huang, Hsin Chen, Kwuang Han Chang, Chih Cheng Hsieh, Ting Hau Chang, Meng Fan Chang, Chia Min Wang, Yi Wen Liu, Tsan Jieh Chen, Chia Hsiang Yang, Herming Chiueh, Jyuo Min Shyu

研究成果: 書貢獻/報告類型會議貢獻

14 引文 (Scopus)

摘要

Ventilator-associated pneumonia (VAP) is the most frequently acquired infection among patients that receive mechanical ventilation in the intensive-care unit (ICU). The mortality rate for VAP lies in the 20-to-50% range and could be even higher in some ICUs. A standard operation procedure to VAP treatment includes a sequence of chest radiography, sputum gram stain, sputum culture, and empiric therapy, initially with antibiotics covering broad pathogens. However, collection of the gram stain and culture of lower respiratory tract specimen is usually not time-efficient (up to 5 days), delaying the initiation of therapy and unacceptable for critically ill patients. A rapid and accurate diagnosis for VAP is therefore crucial, but still unavailable. It is known that microorganisms generate complex metabolites during infection. Fast detection is feasible by examining metabolic wastes in proximal end of the expiratory device, demanding a miniaturized, battery-powered, gas-sensing device. In this work, a fully integrated low-power nose-on-a-chip with a robust learning kernel is developed for such a vital clinical need.
原文英語
主出版物標題Digest of Technical Papers - IEEE International Solid-State Circuits Conference
頁面420-421
頁數2
57
DOIs
出版狀態已發佈 - 2014
事件2014 61st IEEE International Solid-State Circuits Conference, ISSCC 2014 - San Francisco, CA, 美国
持續時間: 二月 9 2014二月 13 2014

其他

其他2014 61st IEEE International Solid-State Circuits Conference, ISSCC 2014
國家美国
城市San Francisco, CA
期間2/9/142/13/14

指紋

Intensive care units
Radiography
Pathogens
Antibiotics
Metabolites
Microorganisms
Gases
Anti-Bacterial Agents
Gram's stain
Artificial Respiration

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

引用此文

Tang, K. T., Chiu, S. W., Shih, C-H., Chang, C. L., Yang, C. M., Yao, D. J., ... Shyu, J. M. (2014). A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia. 於 Digest of Technical Papers - IEEE International Solid-State Circuits Conference (卷 57, 頁 420-421). [6757496] https://doi.org/10.1109/ISSCC.2014.6757496

A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia. / Tang, Kea Tiong; Chiu, Shih Wen; Shih, Chung-Hung; Chang, Chia Ling; Yang, Chia Min; Yao, Da Jeng; Wang, Jen Huo; Huang, Chien Ming; Chen, Hsin; Chang, Kwuang Han; Hsieh, Chih Cheng; Chang, Ting Hau; Chang, Meng Fan; Wang, Chia Min; Liu, Yi Wen; Chen, Tsan Jieh; Yang, Chia Hsiang; Chiueh, Herming; Shyu, Jyuo Min.

Digest of Technical Papers - IEEE International Solid-State Circuits Conference. 卷 57 2014. p. 420-421 6757496.

研究成果: 書貢獻/報告類型會議貢獻

Tang, KT, Chiu, SW, Shih, C-H, Chang, CL, Yang, CM, Yao, DJ, Wang, JH, Huang, CM, Chen, H, Chang, KH, Hsieh, CC, Chang, TH, Chang, MF, Wang, CM, Liu, YW, Chen, TJ, Yang, CH, Chiueh, H & Shyu, JM 2014, A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia. 於 Digest of Technical Papers - IEEE International Solid-State Circuits Conference. 卷 57, 6757496, 頁 420-421, 2014 61st IEEE International Solid-State Circuits Conference, ISSCC 2014, San Francisco, CA, 美国, 2/9/14. https://doi.org/10.1109/ISSCC.2014.6757496
Tang KT, Chiu SW, Shih C-H, Chang CL, Yang CM, Yao DJ 等. A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia. 於 Digest of Technical Papers - IEEE International Solid-State Circuits Conference. 卷 57. 2014. p. 420-421. 6757496 https://doi.org/10.1109/ISSCC.2014.6757496
Tang, Kea Tiong ; Chiu, Shih Wen ; Shih, Chung-Hung ; Chang, Chia Ling ; Yang, Chia Min ; Yao, Da Jeng ; Wang, Jen Huo ; Huang, Chien Ming ; Chen, Hsin ; Chang, Kwuang Han ; Hsieh, Chih Cheng ; Chang, Ting Hau ; Chang, Meng Fan ; Wang, Chia Min ; Liu, Yi Wen ; Chen, Tsan Jieh ; Yang, Chia Hsiang ; Chiueh, Herming ; Shyu, Jyuo Min. / A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia. Digest of Technical Papers - IEEE International Solid-State Circuits Conference. 卷 57 2014. 頁 420-421
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