尋找研究成果

10 引文 (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., 一月 29 2018, (接受/付印) 於 : Journal of Medicinal Chemistry.

研究成果: 雜誌貢獻文章

tau Proteins
Histone Deacetylase Inhibitors
Alzheimer Disease
Hydroxamic Acids
Phenotype
11 引文 (Scopus)
AMP-activated protein kinase
High Fat Diet
Adenosine Monophosphate
high fat diet
Nutrition
10 引文 (Scopus)

5-Demethyltangeretin is more potent than tangeretin in inhibiting dimethylbenz(a)anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin tumorigenesis

Ma, N., Lai, C. S., Chung, C. H., Yang, J. M., Hsu, K. C., Chen, C. Y., Chung, T. S., Li, S., Ho, C. T. & Pan, M. H., 2014, 於 : Journal of Functional Foods. 11, C, p. 528-537 10 p.

研究成果: 雜誌貢獻文章

Tetradecanoylphorbol Acetate
skin (animal)
carcinogenesis
Carcinogenesis
acetates
11 引文 (Scopus)

5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6] naphthyridin-6-ones and related compounds as TOP1-targeting agents: Influence of structure on the ternary cleavable complex formation

Kerrigan, J. E., Pilch, D. S., Ruchelman, A. L., Zhou, N., Liu, A., Liu, L-F. & LaVoie, E. J., 十月 20 2003, 於 : Bioorganic and Medicinal Chemistry Letters. 13, 20, p. 3395-3399 5 p.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Crystal structure
Topotecan
DNA Cleavage
X-Rays
88 引文 (Scopus)

5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity

Ruchelman, A. L., Singh, S. K., Ray, A., Wu, X. H., Yang, J. M., Li, T. K., Liu, A., Liu, L-F. & LaVoie, E. J., 五月 1 2003, 於 : Bioorganic and Medicinal Chemistry. 11, 9, p. 2061-2073 13 p.

研究成果: 雜誌貢獻文章

Naphthyridines
Type I DNA Topoisomerase
Antineoplastic Agents
Tumors
Nude Mice
12 引文 (Scopus)

5-HT modulates multiple conductances in immature rat rostral ventrolateral medulla neurones in vitro

Hwang, L. L. & Dun, N. J., 五月 15 1999, 於 : Journal of Physiology. 517, 1, p. 217-228 12 p.

研究成果: 雜誌貢獻文章

Serotonin
Neurons
Membranes
In Vitro Techniques
Tetrodotoxin
11 引文 (Scopus)

5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro

Hwang, L-L. & Dun, N. J., 九月 1998, 於 : Journal of Neurophysiology. 80, 3, p. 1033-1041 9 p.

研究成果: 雜誌貢獻文章

Serotonin
Neurons
Receptor, Serotonin, 5-HT1A
Serotonin Receptors
In Vitro Techniques
23 引文 (Scopus)

5′CpG island hypermethylation and aberrant transcript splicing both contribute to the inactivation of the FHIT gene in resected non-small cell lung cancer

Tzao, C., Tsai, H. Y., Chen, J. T., Chen, C. Y. & Wang, Y. C., 九月 2004, 於 : European Journal of Cancer. 40, 14, p. 2175-2183 9 p.

研究成果: 雜誌貢獻文章

Histidine
Islands
Non-Small Cell Lung Carcinoma
Genes
Allelic Imbalance

5色美人餐:聰明吃,改善體質真簡單

Yang, S-H. & 黃淑惠, 四月 2 2004, 三味文化事業有限公司. 120 p.

研究成果: 报告类型書籍

5-氟尿嘧啶單獨或併用遊離輻射治療人類結腸直腸癌細胞之效果

Hwang, J-J., Chen, P-Y., 鄧文炳(Win-Ping D, Hwang, J-Y., Lin, G-L., Ngo, F. Q. H., Fu, B-S. & Lin, F-J., 1999, 於 : 放射治療與腫瘤學. 6, 2, p. 73-82 10 p.

研究成果: 雜誌貢獻文章

Ionizing Radiation
Fluorouracil
Colorectal Neoplasms
Radiation
Glutathione
1 引文 (Scopus)

6,7-dihydroxy-2-(4′-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway

Chiu, C. F., Lai, G. Y., Chen, C. H., Chiu, C. C., Hung, S. W. & Chang, C. F., 一月 1 2019, 於 : Drug Design, Development and Therapy. 13, p. 1609-1621 13 p.

研究成果: 雜誌貢獻文章

開啟存取
HCT116 Cells
Endoplasmic Reticulum Stress
Colorectal Neoplasms
Apoptosis
Cyclin B
43 引文 (Scopus)

60Co contamination in recycled steel resulting in elevated civilian radiation doses: Causes and challenges

Chang, W. P., Chan, C. C. & Wang, J. D., 九月 1997, 於 : Health Physics. 73, 3, p. 465-472 8 p.

研究成果: 雜誌貢獻文章

Steel construction
Steel
Dosimetry
contamination
Contamination
3 引文 (Scopus)
Methylenetetrahydrofolate Reductase (NADPH2)
Vitamin B 12
Stents
Homocysteine
Oxidoreductases
60 引文 (Scopus)

6-Acyl-4-aryl/alkyl-5,7-dihydroxycoumarins as anti-inflammatory agents

Lin, C. M., Huang, S. T., Lee, F. W., Kuo, H. S. & Lin, M. H., 七月 1 2006, 於 : Bioorganic and Medicinal Chemistry. 14, 13, p. 4402-4409 8 p.

研究成果: 雜誌貢獻文章

Coumarins
Hydroxyl Radical
Anti-Inflammatory Agents
Phloroglucinol
Derivatives
21 引文 (Scopus)

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to trail-induced apoptosis via reactive oxygen species-mediated increase of dr5

Chen, C. Y., Tai, C. J., Cheng, J. T., Zheng, J. J., Chen, Y. Z., Liu, T. Z., Yiin, S. J. & Chern, C. L., 五月 12 2010, 於 : Journal of Agricultural and Food Chemistry. 58, 9, p. 5604-5611 8 p.

研究成果: 雜誌貢獻文章

Hepatoblastoma
Hep G2 Cells
reactive oxygen species
Reactive Oxygen Species
apoptosis
22 引文 (Scopus)

6-Substituted 6H-dibenzo[c,h][2,6]naphthyridin-5-ones: Reversed lactam analogues of ARC-111 with potent topoisomerase I-targeting activity and cytotoxicity

Zhu, S., Ruchelman, A. L., Zhou, N., Liu, A., Liu, L-F. & LaVoie, E. J., 五月 1 2006, 於 : Bioorganic and Medicinal Chemistry. 14, 9, p. 3131-3143 13 p.

研究成果: 雜誌貢獻文章

Lactams
Type I DNA Topoisomerase
Cytotoxicity
Topotecan
Tumor Cell Line
59 引文 (Scopus)

7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents

Chang, J. Y., Hsieh, H. P., Chang, C. Y., Hsu, K. S., Chiang, Y. F., Chen, C. M., Kuo, C. C. & Liou, J. P., 十一月 16 2006, 於 : Journal of Medicinal Chemistry. 49, 23, p. 6656-6659 4 p.

研究成果: 雜誌貢獻文章

Tubulin Modulators
Sulfonamides
Colchicine
Cell growth
Display devices
10 引文 (Scopus)

7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration

Tsai, C. C., Liu, H. F., Hsu, K. C., Yang, J. M., Chen, C., Liu, K. K., Hsu, T. S. & Chao, J. I., 四月 1 2011, 於 : Biochemical Pharmacology. 81, 7, p. 856-865 10 p.

研究成果: 雜誌貢獻文章

Cytoskeleton
Cell Movement
Myosin Light Chains
Cells
Actins
14 引文 (Scopus)
1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Epidermal Growth Factor Receptor
Smooth Muscle Myocytes
Cell Movement
32 引文 (Scopus)

8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity

Li, D., Zhao, B., Sim, S. P., Li, T. K., Liu, A., Liu, L-F. & LaVoie, E. J., 八月 15 2003, 於 : Bioorganic and Medicinal Chemistry. 11, 17, p. 3795-3805 11 p.

研究成果: 雜誌貢獻文章

Phenanthridines
Type I DNA Topoisomerase
Cytotoxicity
Cell proliferation
Assays

836 10-years experience in cystitis glandularis

Chang, C. H. C., Chen, K-K., Lin, T. L., Pan, C-C., Chang, Y-H., Huang, J., Kuo, J-Y., Chung, H-J. & Lin, T. L., 四月 1 2015, 於 : European Urology, Supplements. 14, 2, p. e836

研究成果: 雜誌貢獻文章

8 Growth arrest DMA damage-inducible gene 45 β in human hepatocellular carcinoma

Yen, Y., 十二月 1 2005, Molecular Genetics, Liver Carcinoma, and Pancreatic Carcinoma. Hayat, M. A. (編輯). p. 207-215 9 p. (Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas; 卷 3).

研究成果: 書貢獻/報告類型章節

Dynamic mechanical analysis
Genes
2 引文 (Scopus)

99mTc pyrene derivative complex causes double-strand breaks in dsDNA mainly through cluster-mediated indirect effect in aqueous solution

Chung, W. J., Cui, Y., Huang, F. Y. J., Tu, T. H., Yang, T. S., Lo, J. M., Chiang, C. S. & Hsu, I. C., 九月 22 2014, 於 : PLoS One. 9, 9, e108162.

研究成果: 雜誌貢獻文章

Dimethyl Sulfoxide
aqueous solutions
dimethyl sulfoxide
chemical derivatives
Derivatives
7 引文 (Scopus)

99mtc-trodat-1 spect in healthy and 6-ohda lesioned parkinsonian monkeys: comparison with f-fdopa pet

Huang, W. S., MA, K. H., Chou, Y. H., Chen, C. Y., Liu, R. S. & Liu, J. C., 一月 1 2003, 於 : Nuclear Medicine Communications. 24, 1, p. 77-83 7 p.

研究成果: 雜誌貢獻文章

Pets
Haplorhini
Parkinson Disease
Positron-Emission Tomography
Single-Photon Emission-Computed Tomography

99mTc-TRODAT-1 SPECT in healthy and 6-OHDA lesioned parkinsonian monkeys: Comparison with 18F-FDOPA PET

Huang, W. S., Ma, K. H., Chou, Y. H., Chen, C. Y., Liu, R. S. & Liu, J. C., 一月 2003, 於 : Nuclear Medicine Communications. 24, 1, p. 77-83 7 p.

研究成果: 雜誌貢獻文章

Oxidopamine
Single-Photon Emission-Computed Tomography
Positron-Emission Tomography
Haplorhini
Parkinson Disease
4 引文 (Scopus)

9-cis retinoic acid induces neurorepair in stroke brain

Yu, S. J., Airavaara, M., Wu, K. J., Harvey, B. K., Liu, H. S., Yang, Y., Zacharek, A., Chen, J. & Wang, Y., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 4512.

研究成果: 雜誌貢獻文章

Stroke
Brain
Lateral Ventricles
Middle Cerebral Artery Infarction
Bromodeoxyuridine
10 引文 (Scopus)
Retinoid X Receptors
Mitochondria
Transcription
Mitochondrial DNA
Membranes
27 引文 (Scopus)

9-Cis-retinoic acid reduces ischemic brain injury in rodents via bone morphogenetic protein

Shen, H., Luo, Y., Kuo, C. C., Deng, X., Fang, C. F., Harvey, B. K., Hoffer, B. J. & Wang, Y., 二月 1 2009, 於 : Journal of Neuroscience Research. 87, 2, p. 545-555 11 p.

研究成果: 雜誌貢獻文章

Bone Morphogenetic Proteins
Brain Injuries
Rodentia
Bone Morphogenetic Protein 7
Tretinoin
14 引文 (Scopus)

A 0.5V 1.27mW nose-on-a-chip for rapid diagnosis of ventilator-associated pneumonia

Tang, K. T., Chiu, S. W., Shih, C-H., Chang, C. L., Yang, C. M., Yao, D. J., Wang, J. H., Huang, C. M., Chen, H., Chang, K. H., Hsieh, C. C., Chang, T. H., Chang, M. F., Wang, C. M., Liu, Y. W., Chen, T. J., Yang, C. H., Chiueh, H. & Shyu, J. M., 2014, Digest of Technical Papers - IEEE International Solid-State Circuits Conference. 卷 57. p. 420-421 2 p. 6757496

研究成果: 書貢獻/報告類型會議貢獻

Intensive care units
Radiography
Pathogens
Antibiotics
Metabolites
7 引文 (Scopus)

A 10-year follow-up of triple-negative breast cancer patients in Taiwan

Lin, C., Chien, S. Y., Kuo, S. J., Chen, L. S., Chen, S. T., Lai, H. W., Chang, T. W. & Chen, D. R., 三月 2012, 於 : Japanese Journal of Clinical Oncology. 42, 3, p. 161-167 7 p., hyr196.

研究成果: 雜誌貢獻文章

Triple Negative Breast Neoplasms
Taiwan
Breast Neoplasms
Survival
Disease-Free Survival
8 引文 (Scopus)

A 10-year follow-up study on suicidal mortality after 1999 Taiwan earthquake

Chen, S. L. S., Lee, C. S., Yen, A. M. F., Chen, H. H., Chan, C. C., Chiu, S. Y. H., Fann, J. C. Y. & Chang, J. C., 八月 1 2016, 於 : Journal of Psychiatric Research. 79, p. 42-49 8 p.

研究成果: 雜誌貢獻文章

Earthquakes
Taiwan
Suicide
Mortality
Age Groups
2 引文 (Scopus)

A 12-year-old boy with an infected ectopic ureter presenting with acute appendicitis-like symptoms and acute scrotum

Chu, W. Y., Tsao, T. F., Chen, S. L., Chang, H. M., Chen, S. M., Chen, C. Y., Lue, K. H. & Sheu, J. N., 六月 2012, 於 : Scandinavian Journal of Urology and Nephrology. 46, 3, p. 208-211 4 p.

研究成果: 雜誌貢獻文章

Scrotum
Appendicitis
Ureter
Kidney
Abdominal Pain

A 17-Year-Old Student with Dysphagia

貢獻的翻譯標題: 一位17歲學生有吞嚥困難Cheng, Y. C., Lou, H. Y., Chang, C-C. & Lin, H-J., 2013, 於 : Gastroenterological Journal of Taiwan. 30, 1, p. 41-42 2 p.

研究成果: 雜誌貢獻文章

48 引文 (Scopus)

A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma

Dong, G., Chanudet, E., Zeng, N., Appert, A., Chen, Y. W., Au, W. Y., Hamoudi, R. A., Watkins, A. J., Ye, H., Liu, H., Gao, Z., Chuang, S. S., Srivastava, G. & Du, M. Q., 三月 15 2011, 於 : Clinical Cancer Research. 17, 6, p. 1440-1451 12 p.

研究成果: 雜誌貢獻文章

Lymphoma, Large B-Cell, Diffuse
Mutation
NF-kappa B
Immunoprecipitation
Comparative Genomic Hybridization
8 引文 (Scopus)

A 20 year clinical and laboratory study of familial b-chronic lymphocytic leukemia in a single kindred

Caporaso, N. E., Whitehouse, J., Bertin, P., Amos, C., Papadopoulos, N., Muller, J., Whang-peng, J., Tucker, M. A., Fleisher, T. A. & Marti, G. E., 一月 1 1991, 於 : Leukemia and Lymphoma. 3, 5-6, p. 331-342 12 p.

研究成果: 雜誌貢獻文章

Lymphocytosis
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Bone Marrow
Spontaneous Remission

A 22-year-old woman had a lung mass

Lee, C. H., Cheng, C. J. & Chan, W. P., 2013, 於 : Annals of the Academy of Medicine Singapore. 42, 2, p. 95-96 2 p.

研究成果: 雜誌貢獻文章

X Ray Computed Tomography
Carcinoid Tumor
Young Adult
Lung Neoplasms
Lung

A 260- μ W down-conversion demodulator for MICS-band receiver

Chang, C. H., Gong, C. S. A., Liou, J. C., Tsou, Y. L., Shiu, F. L., Chiou, H. K. & Tu, P. H., 二月 1 2017, 於 : Journal of Circuits, Systems and Computers. 26, 2, 1750027.

研究成果: 雜誌貢獻文章

Demodulators
Electric power utilization
Feedback
Communication
5 引文 (Scopus)

A 2-year follow-up of swallowing function after radiation therapy in patients with nasopharyngeal carcinoma

Chang, Y. C., Chen, S. Y., Ting, L. L., Peng, S. S. F., Wang, T. C. & Wang, T. G., 十一月 1 2011, 於 : Archives of Physical Medicine and Rehabilitation. 92, 11, p. 1814-1819 6 p.

研究成果: 雜誌貢獻文章

Deglutition
Radiotherapy
Deglutition Disorders
Nasopharyngeal carcinoma
Outcome Assessment (Health Care)
9 引文 (Scopus)

A 3-day anti-Helicobacter pylori therapy is a good alternative for bleeding peptic ulcer patients with Helicobacter pylori infection

Hsieh, Y. H., Lin, H. J., Tseng, G. Y., Perng, C. L., Chang, F. Y. & Lee, S. D., 2001, 於 : Hepato-Gastroenterology. 48, 40, p. 1078-1081 4 p.

研究成果: 雜誌貢獻文章

Helicobacter Infections
Peptic Ulcer
Helicobacter pylori
Hemorrhage
Therapeutics
3 引文 (Scopus)

A 3-year follow-up study on the risk of stroke among patients with conjunctival haemorrhage

Wang, T. J., Keller, J. J., Sheu, J. J. & Lin, H. C., 五月 2013, 於 : Acta Ophthalmologica. 91, 3, p. 226-230 5 p.

研究成果: 雜誌貢獻文章

Stroke
Hemorrhage
Geographic Locations
Health Insurance
Hyperlipidemias

A 43-year-old man with intermittent right throbbing otalgia.

Chen, C-Y., Lee, C-H., Chen, C-Y. & Chan, W. P., 九月 2013, 於 : American Journal of Neuroradiology.

研究成果: 雜誌貢獻簡短的問卷調查

19 引文 (Scopus)

A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation

Lin, S. H., Cheng, C. J., Lee, Y. C., Ye, X., Tsai, W. W., Kim, J., Pasqualini, R., Arap, W., Navone, N. M., Tu, S. M., Hu, M., Yu-Lee, L. Y. & Logothetis, C. J., 九月 4 2008, 於 : Oncogene. 27, 39, p. 5195-5203 9 p.

研究成果: 雜誌貢獻文章

Osteogenesis
Prostatic Neoplasms
Bone and Bones
Osteoblasts
Femur
13 引文 (Scopus)

A 48.6-to-105.2μW machine-learning assisted cardiac sensor SoC for mobile healthcare monitoring

Hsu, S. Y., Ho, Y., Chang, P. Y., Hsu, P. Y., Yu, C. Y., Tseng, Y., Yang, T. Z., Yang, T. F., Chen, R. J., Su, C. & Lee, C. Y., 2013, IEEE Symposium on VLSI Circuits, Digest of Technical Papers. 6578683

研究成果: 書貢獻/報告類型會議貢獻

Learning systems
Monitoring
Sensors
Mobile devices
Feature extraction
2 引文 (Scopus)

A 5' AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma

Weng, J. R., Dokla, E. M. E., Bai, L. Y., Chen, C. S., Chiu, S. J. & Shieh, T. M., 一月 1 2018, (接受/付印) 於 : Basic and Clinical Pharmacology and Toxicology.

研究成果: 雜誌貢獻文章

Enzyme Activators
AMP-Activated Protein Kinases
Autophagy
Squamous Cell Carcinoma
Protein Tyrosine Phosphatases
17 引文 (Scopus)
Obstructive Sleep Apnea
Parkinson Disease
Cohort Studies
Confidence Intervals
Health Insurance
4 引文 (Scopus)

A 65nm CMOS low power impulse radar for respiratory feature extraction

Tseng, S. T., Kao, Y. H., Peng, C. C., Liu, J. Y., Chu, S. C., Hong, G. F., Hsieh, C. H., Hsu, K. T., Liu, W-T., Huang, Y. H., Huang, S. Y. & Chu, T. S., 十一月 25 2015, Proceedings of the 2015 IEEE Radio Frequency Integrated Circuits Symposium, RFIC 2015. Institute of Electrical and Electronics Engineers Inc., 卷 2015-November. p. 251-254 4 p. 7337752

研究成果: 書貢獻/報告類型會議貢獻

Feature extraction
Radar
Sensors
Scanning
Pulmonary diseases
8 引文 (Scopus)

A 65-nm CMOS Low-Power Impulse Radar System for Human Respiratory Feature Extraction and Diagnosis on Respiratory Diseases

Tseng, S. T., Kao, Y. H., Peng, C. C., Liu, J. Y., Chu, S. C., Hong, G. F., Hsieh, C. H., Hsu, K. T., Liu, W. T., Huang, Y. H., Huang, S. Y. & Chu, T. S., 四月 1 2016, 於 : IEEE Transactions on Microwave Theory and Techniques. 64, 4, p. 1029-1041 13 p., 7432046.

研究成果: 雜誌貢獻文章

respiratory diseases
Pulmonary diseases
Radar systems
pattern recognition
radar
7 引文 (Scopus)

A 7-year population study of primary angle closure glaucoma admissions and climate in Taiwan

Hu, C. C., Lin, H. C. & Chen, C. S., 一月 2008, 於 : Ophthalmic Epidemiology. 15, 1, p. 66-72 7 p.

研究成果: 雜誌貢獻文章

Angle Closure Glaucoma
Climate
Taiwan
Population
Humidity

A 9-year-old female with bilateral leg weakness after infuenza vaccination

Tay, S. Y. & Chan, W. P., 十一月 1 2014, 於 : Pediatric Annals. 43, 11, p. 440-441 2 p.

研究成果: 雜誌貢獻文章

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Influenza Vaccines
Muscle Weakness
Human Influenza
Leg

A 9-year-old girl with rhabdomyolysis complicated with iatrogenic calcinosis cutis

Hsu, C. H., Chen, W. Y. & Tsai, T-H., 十月 2009, 於 : Clinical and Experimental Dermatology. 34, 7

研究成果: 雜誌貢獻文章

Calcium Gluconate
Calcinosis
Rhabdomyolysis
Skin Diseases