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出版年份

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

作者

  • Joen-Rong Sheu
2018

Structure-antiplatelet activity relationships of novel ruthenium (ii) complexes: Investigation of its molecular targets

Hsia, C. H., Jayakumar, T., Sheu, J. R., Tsao, S. Y., Velusamy, M., Hsia, C. W., Chou, D. S., Chang, C. C., Chung, C. L., Khamrang, T. & Lin, K. C., 二月 22 2018, 於 : Molecules. 23, 2, 477.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
2019

New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury

Lu, W-J., Lin, K-H., Tseng, M-F., Yuan, K-C., Huang, H-C., Sheu, J-R. & Chen, R-J., 三月 1 2019, 於 : Journal of Cellular and Molecular Medicine. 23, 3, p. 1723-1734 12 p.

研究成果: 雜誌貢獻文章

2018
3 引文 斯高帕斯(Scopus)
2020

Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: Regulation by integrin αiIbβ3 inside-out but not outside-in signals

Hou, S. M., Hsia, C. W., Tsai, C. L., Hsia, C. H., Jayakumar, T., Velusamy, M. & Sheu, J. R., 五月 6 2020, 於 : Journal of Biomedical Science. 27, 1, 60.

研究成果: 雜誌貢獻文章

開啟存取
2017

A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies

Hsia, C. H., Velusamy, M., Sheu, J. R., Khamrang, T., Jayakumar, T., Lu, W. J., Lin, K. H. & Chang, C. C., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 9556.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2016

Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism

Yen, T. L., Wu, M. P., Chung, C. L., Yang, W. B., Jayakumar, T., Geraldine, P., Chou, C. M., Chang, C. Y., Lu, W-J. & Sheu, J. R., 二月 17 2016, 於 : Journal of Biomedical Science. 23, 1, 26.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
2017

Ketamine, a clinically used anesthetic, inhibits vascular smooth muscle cell proliferation via PP2A-activated PI3K/Akt/ERK inhibition

Chang, Y., Li, J. Y., Jayakumar, T., Hung, S. H., Lee, W. C., Manubolu, M., Sheu, J. R. & Hsu, M. J., 十二月 1 2017, 於 : International Journal of Molecular Sciences. 18, 12, 2545.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

New therapeutic agent against arterial thrombosis: An iridium(III)-derived organometallic compound

Hsia, C. W., Velusamy, M., Tsao, J. T., Hsia, C. H., Chou, D. S., Jayakumar, T., Lee, L. W., Li, J. Y. & Sheu, J. R., 十二月 5 2017, 於 : International Journal of Molecular Sciences. 18, 12, 2616.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2020
開啟存取
2019

Protective effects of ammannia baccifera against ccl4-induced oxidative stress in rats

Goodla, L., Manubolu, M., Pathakoti, K., Jayakumar, T., Sheu, J. R., Fraker, M., Tchounwou, P. B. & Poondamalli, P. R., 四月 2 2019, 於 : International Journal of Environmental Research and Public Health. 16, 8, 1440.

研究成果: 雜誌貢獻文章

開啟存取
11 引文 斯高帕斯(Scopus)
2016

The pharmacodynamics of antiplatelet compounds in thrombosis treatment

Jayakumar, T., Yang, C. H., Geraldine, P., Yen, T. L. & Sheu, J. R., 六月 2 2016, 於 : Expert Opinion on Drug Metabolism and Toxicology. 12, 6, p. 615-632 18 p.

研究成果: 雜誌貢獻回顧型文獻

10 引文 斯高帕斯(Scopus)
2017

Honokiol as a specific collagen receptor glycoprotein VI antagonist on human platelets: Functional ex vivo and in vivo studies

Lee, T. Y., Chang, C. C., Lu, W-J., Yen, T. L., Lin, K. H., Geraldine, P., Li, J. Y. & Sheu, J-R., 一月 5 2017, 於 : Scientific Reports. 7, 40002.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2019
開啟存取
1 引文 斯高帕斯(Scopus)

A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis

Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., 一月 1 2019, 於 : Frontiers in Neuroscience. 13, JUN, 635.

研究成果: 雜誌貢獻文章

開啟存取
3 引文 斯高帕斯(Scopus)
2016

Prevention of arterial thrombosis by nobiletin: In vitro and in vivo studies

Lu, W-J., Lin, K. C., Liu, C. P., Lin, C. Y., Wu, H. C., Chou, D. S., Geraldine, P., Huang, S. Y., Hsieh, C. Y. & Sheu, J. R., 二月 1 2016, 於 : Journal of Nutritional Biochemistry. 28, p. 1-8 8 p.

研究成果: 雜誌貢獻文章

20 引文 斯高帕斯(Scopus)
2019
5 引文 斯高帕斯(Scopus)
2018

Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation

Shyu, K. G., Velusamy, M., Hsia, C. W., Yang, C. H., Hsia, C. H., Chou, D. S., Jayakumar, T., Sheu, J. R. & Li, J. Y., 五月 1 2018, 於 : International Journal of Molecular Medicine. 41, 5, p. 2589-2600 12 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)
2019

Suppression of human platelet activation via integrin αiibβ3 outside-in independent signal and reduction of the mortality in pulmonary thrombosis by auraptene

Hsia, C. W., Tsai, C. L., Sheu, J. R., Lu, W. J., Hsia, C. H., Velusamy, M., Jayakumar, T. & Li, J. Y., 十一月 2 2019, 於 : International Journal of Molecular Sciences. 20, 22, 5585.

研究成果: 雜誌貢獻文章

開啟存取
3 引文 斯高帕斯(Scopus)
2017

The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats

Hsu, L. W., Shiao, W. C., Chang, N. C., Yu, M. C., Yen, T. L., Thomas, P. A., Jayakumar, T. & Sheu, J. R., 一月 31 2017, 於 : Chinese Medicine (United Kingdom). 12, 1, 7.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

Structure-activity relationship of three synthesized benzimidazole-based oligosaccharides in human platelet activation

Chang, Y., Hsu, W. H., Yang, W. B., Jayakumar, T., Lee, T. Y., Sheu, J. R., Lu, W. J. & Li, J. Y., 十一月 1 2017, 於 : International Journal of Molecular Medicine. 40, 5, p. 1520-1528 9 p.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

Multi-targeting andrographolide, a novel NF-κB inhibitor, as a potential therapeutic agent for stroke

Yang, C. H., Yen, T. L., Hsu, C. Y., Thomas, P. A., Sheu, J. R. & Jayakumar, T., 八月 1 2017, 於 : International Journal of Molecular Sciences. 18, 8, 1638.

研究成果: 雜誌貢獻回顧型文獻

41 引文 斯高帕斯(Scopus)
2016
34 引文 斯高帕斯(Scopus)
2018

Hinokitiol inhibits migration of A549 lung cancer cells via suppression of MMPs and induction of antioxidant enzymes and apoptosis

Jayakumar, T., Liu, C. H., Wu, G. Y., Lee, T. Y., Manubolu, M., Hsieh, C. Y., Yang, C. H. & Sheu, J. R., 三月 22 2018, 於 : International Journal of Molecular Sciences. 19, 4, 939.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation

Shyu, R. S., Khamrang, T., Sheu, J. R., Hsia, C. W., Velusamy, M., Hsia, C. H., Chou, D. S. & Chang, C. C., 一月 1 2018, 於 : Bioinorganic Chemistry and Applications. 2018, p. 8291393 8291393.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Possible molecular targets of novel ruthenium complexes in antiplatelet therapy

Jayakumar, T., Hsu, C. Y., Khamrang, T., Hsia, C. H., Hsia, C. W., Manubolu, M. & Sheu, J. R., 六月 20 2018, 於 : International Journal of Molecular Sciences. 19, 6, 1818.

研究成果: 雜誌貢獻回顧型文獻

5 引文 斯高帕斯(Scopus)

Novel therapeutic agent against platelet activation in vitro and arterial thrombosis in vivo by morin hydrate

Hsia, C. W., Wu, M. P., Velusamy, M., Hsia, C. H., Chou, D. S., Tsai, C. L., Hsu, C. Y., Jayakumar, T., Chung, C. L. & Sheu, J. R., 八月 13 2018, 於 : International Journal of Molecular Sciences. 19, 8, 2386.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)
開啟存取

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., 十一月 14 2018, 於 : Journal of Clinical Medicine. 7, 11

研究成果: 雜誌貢獻文章

Mechanism of free radical generation in platelets and primary hepatocytes: A novel electron spin resonance study

Wang, C. L., Yang, P. S., Tsao, J. T., Jayakumar, T., Wang, M. J., Sheu, J. R. & Chou, D. S., 一月 1 2018, 於 : Molecular Medicine Reports. 17, 1, p. 2061-2069 9 p.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
2020

Biomass and Lipid Production Potential of an Indian Marine Algal Isolate Tetraselmis striata BBRR1

Boopathy, A. B., Jayakumar, T., Chinnasamy, S., Rajaram, M. G., Mohan, N., Nagaraj, S., Rengasamy, R., Manubolu, M., Sheu, J. R. & Chang, C. C., 一月 1 2020, 於 : Energies. 13, 2, 341.

研究成果: 雜誌貢獻文章

開啟存取
2019

Esculetin, A coumarin derivative, prevents thrombosis: Inhibitory signaling on PLCγ2-PKC-AKT activation in human platelets

Hsia, C. W., Lin, K. C., Lee, T. Y., Hsia, C. H., Chou, D. S., Jayakumar, T., Velusamy, M. & Sheu, J. R., 六月 1 2019, 於 : International Journal of Molecular Sciences. 20, 11, 2731.

研究成果: 雜誌貢獻文章

開啟存取
3 引文 斯高帕斯(Scopus)
2018

Structure⁻Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases

Yang, C. H., Hsia, C. W., Jayakumar, T., Sheu, J. R., Hsia, C. H., Khamrang, T., Chen, Y. J., Manubolu, M. & Chang, Y., 十一月 19 2018, 於 : International Journal of Molecular Sciences. 19, 11

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
2020

Ruthenium derivatives attenuate LPS-induced inflammatory responses and liver injury via suppressing NF-κB signaling and free radical production

Jayakumar, T., Huang, H. C., Hsia, C. W., Fong, T. H., Khamrang, T., Velusamy, M., Manubolu, M., Sheu, J. R. & Hsia, C. H., 三月 2020, 於 : Bioorganic Chemistry. 96, 103639.

研究成果: 雜誌貢獻文章

2017
開啟存取

Development of benzimidazole derivatives as novel anti-platelet drugs

Yao, W. C., Yuan, L. T., Yang, W. B., Hsia, C. H., Huang, L. T., Lee, T. Y., Sheu, J. R., Lu, W-J., Jayakumar, T. & Chen, R. J., 一月 1 2017, 於 : Current Pharmaceutical Biotechnology. 18, 7, p. 594-605 12 p.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
2020
開啟存取
2016

Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation

Shen, M. Y., Chen, F. Y., Hsu, J. F., Fu, R. H., Chang, C. M., Chang, C. T., Liu, C. H., Wu, J. R., Lee, A. S., Chan, H. C., Sheu, J. R., Lin, S. Z., Shyu, W. C., Sawamura, T., Chang, K. C., Hsu, C. Y. & Chen, C. H., 三月 10 2016, 於 : Blood. 127, 10, p. 1336-1345 10 p.

研究成果: 雜誌貢獻文章

34 引文 斯高帕斯(Scopus)
2017

A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice

Sheu, J. R., Chen, Z. C., Jayakumar, T., Chou, D. S., Yen, T. L., Lee, H. N., Pan, S. H., Hsia, C. H., Yang, C. H. & Hsieh, C. Y., 二月 6 2017, 於 : Scientific Reports. 7, 42277.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
2018

Molecular pharmacology and pathology of strokes

Sheu, J. R., 一月 1 2018, 於 : International Journal of Molecular Sciences. 19, 12, 4103.

研究成果: 雜誌貢獻社論

Mechanisms of TQ-6, a Novel Ruthenium-Derivative Compound, against Lipopolysaccharide-Induced In Vitro Macrophage Activation and Liver Injury in Experimental Mice: The Crucial Role of p38 MAPK and NF-κB Signaling

Hsia, C-H., Velusamy, M., Jayakumar, T., Chen, Y-J., Hsia, C-W., Tsai, J-H., Teng, R-D. & Sheu, J-R., 十一月 19 2018, 於 : Cells. 7, 11

研究成果: 雜誌貢獻文章

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., 二月 1 2018, 於 : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)
2017

Antiplatelet activity of a newly synthesized novel ruthenium (II): A potential role for Akt/JNK signaling

Khamrang, T., Hung, K. C., Hsia, C. H., Hsieh, C. Y., Velusamy, M., Jayakumar, T. & Sheu, J. R., 五月 1 2017, 於 : International Journal of Molecular Sciences. 18, 5, 916.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Nobiletin, a citrus flavonoid, activates Vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms

Jayakumar, T., Lin, K. C., Lu, W-J., Lin, C. Y., Pitchairaj, G., Li, J. Y. & Sheu, J-R., 一月 1 2017, 於 : International Journal of Molecular Medicine. 39, 1, p. 174-182 9 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
8 引文 斯高帕斯(Scopus)
2016

Nobiletin, a Polymethoxylated Flavone, Inhibits Glioma Cell Growth and Migration via Arresting Cell Cycle and Suppressing MAPK and Akt Pathways

Lien, L. M., Wang, M. J., Chen, R. J., Chiu, H. C., Wu, J. L., Shen, M. Y., Chou, D. S., Sheu, J. R., Lin, K. H. & Lu, W-J., 二月 1 2016, 於 : Phytotherapy Research. 30, 2, p. 214-221 8 p.

研究成果: 雜誌貢獻文章

31 引文 斯高帕斯(Scopus)
2018

Analysis of Titin in Red and White Muscles: Crucial Role on Muscle Contractions Using a Fish Model

Wu, M. P., Chang, N. C., Chung, C. L., Chiu, W. C., Hsu, C. C., Chen, H. M., Sheu, J. R., Jayakumar, T., Chou, D. S. & Fong, T. H., 十一月 18 2018, 於 : BioMed Research International. 2018, p. 5816875 11 p., 5816875.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

Biofuel and biochemical analysis of amphora coffeaeformis RR03, a novel marine diatom, cultivated in an open raceway pond

Rajaram, M. G., Nagaraj, S., Manjunath, M., Boopathy, A. B., Kurinjimalar, C., Rengasamy, R., Jayakumar, T., Sheu, J. R. & Li, J. Y., 六月 1 2018, 於 : Energies. 11, 6, en11061341.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)