尋找研究成果

搜尋概念
已選取的篩選器

出版年份

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

作者

  • Yun Yen
2016

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells

Chen, Y. R., Tsou, B., Hu, S., Ma, H., Liu, X., Yen, Y. & Ann, D. K., 一月 1 2016, 於 : Oncotarget. 7, 2, p. 1984-1999 16 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing

Clark, A. J., Wiley, D. T., Zuckerman, J. E., Webster, P., Chao, J., Lin, J., Yen, Y. & Davis, M. E., 四月 5 2016, 於 : Proceedings of the National Academy of Sciences of the United States of America. 113, 14, p. 3850-3854 5 p.

研究成果: 雜誌貢獻文章

85 引文 斯高帕斯(Scopus)

Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker

Zhang, L., Chen, Z., Xue, D., Zhang, Q., Liu, X., Luh, F., Hong, L., Zhang, H., Pan, F., Liu, Y., Chu, P., Zheng, S., Lou, G. & Yen, Y., 十一月 1 2016, 於 : Oncology Reports. 36, 5, p. 2489-2500 12 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
2017

Overexpression of uridine-cytidine kinase 2 correlates with breast cancer progression and poor prognosis

Shen, G., He, P., Mao, Y., Li, P., Luh, F., Ding, G., Liu, X. & Yen, Y., 六月 1 2017, 於 : Journal of Breast Cancer. 20, 2, p. 132-141 10 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)
2018

Phase IB trial of ixabepilone and vorinostat in metastatic breast cancer

Luu, T., Kim, K. P., Blanchard, S., Anyang, B., Hurria, A., Yang, L., Beumer, J. H., Somlo, G. & Yen, Y., 一月 1 2018, 於 : Breast Cancer Research and Treatment. 167, 2, p. 469-478 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Dai, Y., Wang, C., Chiu, L. Y., Abbasi, K., Tolbert, B. S., Sauvé, G., Yen, Y. & Liu, C. C., 十月 15 2018, 於 : Biosensors and Bioelectronics. 117, p. 60-67 8 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)
2019

Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway

Wakabayashi, G., Lee, Y. C., Luh, F., Kuo, C. N., Chang, W. C. & Yen, Y., 十二月 5 2019, 於 : Journal of Biomedical Science. 26, 1, 96.

研究成果: 雜誌貢獻回顧型文獻

開啟存取
2017

Mechanism and clinical properties of stembios cell therapy: Induction of early osseointegration in novel dental implants

Weng, C. C., Ou, K. L., Wu, C. Y., Huang, Y. H., Wang, J., Yen, Y., Cheng, H. Y. & Lin, Y. H., 2017, 於 : International Journal of Oral and Maxillofacial Implants. 32, 1, p. e47-e54

研究成果: 雜誌貢獻文章

2018

Differences in silencing of mismatched targets by sliced versus diced siRNAs

Sun, G., Wang, J., Huang, Y., Yuan, C. W. Y., Zhang, K., Hu, S., Chen, L., Lin, R. J., Yen, Y. & Riggs, A. D., 一月 1 2018, 於 : Nucleic Acids Research. 46, 13, p. 6806-6822 17 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2017

Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers

Ding, J., Kuo, M. L., Su, L., Xue, L., Luh, F., Zhang, H., Wang, J., Lin, T. G., Zhang, K., Chu, P., Zheng, S., Liu, X. & Yen, Y., 五月 1 2017, 於 : Carcinogenesis. 38, 5, p. 519-531 13 p., bgx022.

研究成果: 雜誌貢獻文章

24 引文 斯高帕斯(Scopus)
2018

Benefits and harms of the centers for medicare & medicaid services ruling on next-generation sequencing

Luh, F. & Yen, Y., 九月 1 2018, 於 : JAMA oncology. 4, 9, p. 1171-1172 2 p.

研究成果: 雜誌貢獻簡短的問卷調查

2017

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

Huang, Y. J., Yang, C. K., Wei, P. L., Huynh, T. T., Whang-Peng, J., Meng, T. C., Hsiao, M., Tzeng, Y. M., Wu, A. T. & Yen, Y., 二月 28 2017, 於 : Journal of hematology & oncology. 10, 1, p. 60 1 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)
2019

miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2

Chen, H. Y., Lang, Y. D., Lin, H. N., Liu, Y. R., Liao, C. C., Nana, A. W., Yen, Y. & Chen, R. H., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 9687.

研究成果: 雜誌貢獻文章

開啟存取
3 引文 斯高帕斯(Scopus)
2018

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., 三月 1 2018, 於 : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2019
開啟存取
1 引文 斯高帕斯(Scopus)
2016

Research of StemBios cell therapy on dental implants containing nanostructured surfaces: Biomechanical behaviors, microstructural characteristics, and clinical trial

Ou, K. L., Weng, C. C., Wu, C. C., Lin, Y. H., Chiang, H. J., Yang, T. S., Wang, J., Yen, Y., Cheng, H. Y. & Sugiatno, E., 二月 1 2016, 於 : Implant Dentistry. 25, 1, p. 63-73 11 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)
2018

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., 九月 15 2018, 於 : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

研究成果: 雜誌貢獻文章

36 引文 斯高帕斯(Scopus)
2017

Does aspirin use reduce the risk for cancer?

Usman, I., Yang, H. C., Jian, W. S., Yen, Y. & Li, Y. C., 二月 1 2017, 於 : Journal of Investigative Medicine. 65, 2, p. 391-392 2 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2 引文 斯高帕斯(Scopus)
2019

Does long-term use of antidiabetic drugs changes cancer risk?

Liu, Y. C., Nguyen, P. A., Humayun, A., Chien, S. C., Yang, H. C., Asdary, R. N., Syed-Abdul, S., Hsu, M. H., Moldovan, M., Yen, Y., Li, Y. C., Jian, W. S. & Iqbal, U., 十月 1 2019, 於 : Medicine (United States). 98, 40, p. e17461 e17461.

研究成果: 雜誌貢獻文章

開啟存取
1 引文 斯高帕斯(Scopus)

Randomized trial of oral cyclophosphamide versus oral cyclophosphamide with celecoxib for recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer

Gupta, R., Cristea, M., Frankel, P., Ruel, C., Chen, C., Wang, Y., Morgan, R., Leong, L., Chow, W., Koczywas, M., Koehler, S., Lim, D., Luu, T., Martel, C., McNamara, M., Somlo, G., Twardowski, P., Yen, Y., Idorenyi, A., Raechelle, T. 及其他2, Carroll, M. & Chung, V., 一月 1 2019, 於 : Cancer Treatment and Research Communications. 21, 100155.

研究成果: 雜誌貢獻文章

Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer

Lu, H., Wang, C., Xue, L., Zhang, Q., Luh, F., Wang, J., Lin, T. G., Yen, Y. & Liu, X., 一月 1 2019, 於 : Journal of Oncology. 2019, 2316237.

研究成果: 雜誌貢獻文章

開啟存取
2 引文 斯高帕斯(Scopus)
2016

Observation of polarization and thickness dependent third-harmonic generation in multilayer black phosphorus

Wu, H. Y., Yen, Y. & Liu, C. H., 十二月 26 2016, 於 : Applied Physics Letters. 109, 26, 261902.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)
2019

Rrm2b deletion causes mitochondrial metabolic defects in renal tubules

Chen, Y. F., Lin, I. H., Guo, Y. R., Chiu, W. J., Wu, M. S., Jia, W. & Yen, Y., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 1 p., 13238.

研究成果: 雜誌貢獻文章

開啟存取
2016

The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells

Chen, C. W., Tsao, N., Huang, L. Y., Yen, Y., Liu, X., Lehman, C., Wang, Y. H., Tseng, M. C., Chen, Y. J., Ho, Y. C., Chen, C. F. & Chang, Z. F., 八月 2 2016, 於 : Cell Reports. 16, 5, p. 1287-1299 13 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)
2017

Pilot trial of CRLX101 in patients with advanced, chemotherapyrefractory gastroesophageal cancer

Chao, J., Lin, J., Frankel, P., Clark, A. J., Wiley, D. T., Garmey, E., Fakih, M., Lim, D., Chung, V., Luevanos, E., Eliasof, S., Davis, M. E. & Yen, Y., 十二月 1 2017, 於 : Journal of Gastrointestinal Oncology. 8, 6, p. 962-969 8 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2018

The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes

Wang, Y. C., Chang, K. C., Lin, B. W., Lee, J. C., Lai, C. H., Lin, L. J., Yen, Y., Lin, C. S., Yang, S. J., Lin, P. C., Lee, C. T. & Hung, L. Y., 六月 1 2018, 於 : Experimental and Molecular Medicine. 50, 6, p. 70 70.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
5 引文 斯高帕斯(Scopus)

Web-based platform vs genetic counselors in educating patients about carrier results from exome sequencing

Yen, Y. & Luh, F., 七月 1 2018, 於 : JAMA Internal Medicine. 178, 7, p. 998-999 2 p.

研究成果: 雜誌貢獻快報

1 引文 斯高帕斯(Scopus)

Ribonucleotide reductase subunit M2B deficiency leads to mitochondrial permeability transition pore opening and is associated with aggressive clinicopathologic manifestations of breast cancer

Xue, L., Liu, X., Wang, Q., Liu, C. Q., Chen, Y., Jia, W., Hsie, R., Chen, Y., Luh, F., Zheng, S. & Yen, Y., 一月 1 2018, 於 : American Journal of Translational Research. 10, 11, p. 3635-3649 15 p., AJTR0084684.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
2017
6 引文 斯高帕斯(Scopus)
2018

A homozygous variant in RRM2B is associated with severe metabolic acidosis and early neonatal death

Penque, B. A., Su, L., Wang, J., Ji, W., Bale, A., Luh, F., Fulbright, R. K., Sarmast, U., Sega, A. G., Konstantino, M., Spencer-Manzon, M., Pierce, R., Yen, Y. & Lakhani, S. A., 一月 1 2018, (接受/付印) 於 : European Journal of Medical Genetics.

研究成果: 雜誌貢獻文章

2019

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers

Chen, Y. F., Wang, Y. H., Lei, C. S., Changou, C. A., Davis, M. E. & Yen, Y., 十月 23 2019, 於 : Journal of Biomedical Science. 26, 1, 1 p.

研究成果: 雜誌貢獻回顧型文獻

開啟存取

The Ambivalent Role of lncRNA Xist in Carcinogenesis

Chen, Y. K. & Yen, Y., 四月 15 2019, 於 : Stem Cell Reviews and Reports. 15, 2, p. 314-323 10 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Chicken-Derived Humanized Antibody Targeting a Novel Epitope F2pep of Fibroblast Growth Factor Receptor 2: Potential Cancer Therapeutic Agent

Tsai, K. C., Chang, C. D., Cheng, M. H., Lin, T. Y., Lo, Y. N., Yang, T. W., Chang, F. L., Chiang, C. W., Lee, Y. C. & Yen, Y., 一月 31 2019, 於 : ACS Omega. 4, 1, p. 2387-2397 11 p.

研究成果: 雜誌貢獻文章

開啟存取
1 引文 斯高帕斯(Scopus)
2016

Novel regulators and molecular mechanisms of p53R2 and its disease relevance

Cho, E. C. & Yen, Y., 四月 1 2016, 於 : Biochimie. 123, p. 81-84 4 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)
2017

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Shih, J. W., Chiang, W. F., Wu, A. T. H., Wu, M. H., Wang, L. Y., Yu, Y. L., Hung, Y. W., Wang, W. C., Chu, C. Y., Hung, C. L., Changou, C. A., Yen, Y. & Kung, H. J., 六月 22 2017, 於 : Nature Communications. 8, 15874.

研究成果: 雜誌貢獻文章

49 引文 斯高帕斯(Scopus)
2016

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., 四月 27 2016, 於 : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2020

Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats

Yang, Y. C. S. H., Chang, H. W., Lin, I. H., Chien, L. N., Wu, M. J., Liu, Y. R., Chu, P. G., Xie, G., Dong, F., Jia, W., Chang, V. H. S. & Yen, Y., 十二月 1 2020, 於 : Scientific Reports. 10, 1, 866.

研究成果: 雜誌貢獻文章

開啟存取
2016
10 引文 斯高帕斯(Scopus)
2017

1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma

Liu, Y. M., HuangFu, W. C., Huang, H. L., Wu, W. C., Chen, Y. L., Yen, Y., Huang, H. L., Nien, C. Y., Lai, M. J., Pan, S. L. & Liou, J. P., 十一月 10 2017, 於 : European Journal of Medicinal Chemistry. 140, p. 84-91 8 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2018

Global DNA methylation analysis reveals miR-214-3p contributes to cisplatin resistance in pediatric intracranial nongerminomatous malignant germ cell tumors

Hsieh, T. H., Liu, Y. R., Chang, T. Y., Liang, M. L., Chen, H. H., Wang, H. W., Yen, Y. & Wong, T-T., 三月 27 2018, 於 : Neuro-Oncology. 20, 4, p. 519-530 12 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
2016

A phase I pharmacodynamic study of GTI-2040, an antisense oligonucleotide against ribonuclotide reductase, in acute leukemias: a California Cancer Consortium study

Kirschbaum, M. H., Frankel, P., Synold, T. W., Xie, Z., Yen, Y., Popplewell, L., Chen, R., Aljitawi, O., Tuscano, J. M., Chan, K. K. & Newman, E. M., 十月 2 2016, 於 : Leukemia and Lymphoma. 57, 10, p. 2307-2314 8 p.

研究成果: 雜誌貢獻文章

2019

DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Chen, C. W., Li, Y., Hu, S., Zhou, W., Meng, Y., Li, Z., Zhang, Y., Sun, J., Bo, Z., DePamphilis, M. L., Yen, Y., Han, Z. & Zhu, W., 三月 2019, 於 : Oncogene.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2018

A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma

El-Khoueiry, A. B., O’Donnell, R., Semrad, T. J., Mack, P., Blanchard, S., Bahary, N., Jiang, Y., Yen, Y., Wright, J., Chen, H., Lenz, H. J. & Gandara, D. R., 五月 1 2018, 於 : Cancer Chemotherapy and Pharmacology. 81, 5, p. 957-963 7 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)
2016

Polymeric nanoparticles and cancer: Lessons learnt from CRLX101

Gritli, I., Garmey, E., Eliasof, S., Tellez, A., Davis, M. E. & Yun, Y., 2016, Privileged Scaffolds in Medicinal Chemistry: Design, Synthesis, Evaluation. 51 編輯 Royal Society of Chemistry, 卷 2016-January. p. 199-232 34 p. (RSC Drug Discovery Series; 卷 2016-January, 編號 51).

研究成果: 書貢獻/報告類型章節

1 引文 斯高帕斯(Scopus)
2019

Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma

Madamsetty, V. S., Pal, K., Dutta, S. K., Wang, E., Thompson, J. R., Banerjee, R. K., Caulfield, T. R., Mody, K., Yen, Y., Mukhopadhyay, D. & Huang, H-S., 十月 4 2019, 於 : Bioconjugate Chemistry.

研究成果: 雜誌貢獻文章

2016

Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer

Wu, J., Zhang, S., Shan, J., Hu, Z., Liu, X., Chen, L., Ren, X., Yao, L., Sheng, H., Li, L., Ann, D., Yen, Y., Wang, J. & Wang, X., 七月 1 2016, 於 : Cancer Letters. 376, 2, p. 284-292 9 p.

研究成果: 雜誌貢獻文章

37 引文 斯高帕斯(Scopus)

Precision Medicine and Pancreatic Cancer

Farrell, J. J., Moughan, J., Wong, J. L., Regine, W. F., Schaefer, P., Benson, A. B., Macdonald, J. S., Liu, X., Yen, Y., Lai, R., Zheng, Z., Bepler, G., Guha, C. & Elsaleh, H., 十一月 1 2016, 於 : Pancreas. 45, 10, p. 1485-1493 9 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Kuo, M. L., Lee, M. B. E., Tang, M., Den Besten, W., Hu, S., Sweredoski, M. J., Hess, S., Chou, C. M., Changou, C. A., Su, M., Jia, W., Su, L. & Yen, Y., 一月 6 2016, 於 : Scientific Reports. 6, 18846.

研究成果: 雜誌貢獻文章

23 引文 斯高帕斯(Scopus)