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出版年份

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

作者

  • Yun Yen
2016

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells

Chen, Y. R., Tsou, B., Hu, S., Ma, H., Liu, X., Yen, Y. & Ann, D. K., 一月 1 2016, 於 : Oncotarget. 7, 2, p. 1984-1999 16 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

Polymeric nanoparticles and cancer: Lessons learnt from CRLX101

Gritli, I., Garmey, E., Eliasof, S., Tellez, A., Davis, M. E. & Yun, Y., 2016, Privileged Scaffolds in Medicinal Chemistry: Design, Synthesis, Evaluation. 51 編輯 Royal Society of Chemistry, 卷 2016-January. p. 199-232 34 p. (RSC Drug Discovery Series; 卷 2016-January, 編號 51).

研究成果: 書貢獻/報告類型章節

3 引文 斯高帕斯(Scopus)

CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing

Clark, A. J., Wiley, D. T., Zuckerman, J. E., Webster, P., Chao, J., Lin, J., Yen, Y. & Davis, M. E., 四月 5 2016, 於 : Proceedings of the National Academy of Sciences of the United States of America. 113, 14, p. 3850-3854 5 p.

研究成果: 雜誌貢獻文章

90 引文 斯高帕斯(Scopus)
2018

Differences in silencing of mismatched targets by sliced versus diced siRNAs

Sun, G., Wang, J., Huang, Y., Yuan, C. W. Y., Zhang, K., Hu, S., Chen, L., Lin, R. J., Yen, Y. & Riggs, A. D., 一月 1 2018, 於 : Nucleic Acids Research. 46, 13, p. 6806-6822 17 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Ribonucleotide reductase subunit M2B deficiency leads to mitochondrial permeability transition pore opening and is associated with aggressive clinicopathologic manifestations of breast cancer

Xue, L., Liu, X., Wang, Q., Liu, C. Q., Chen, Y., Jia, W., Hsie, R., Chen, Y., Luh, F., Zheng, S. & Yen, Y., 一月 1 2018, 於 : American Journal of Translational Research. 10, 11, p. 3635-3649 15 p., AJTR0084684.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
2019

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Schmit, S. L., Edlund, C. K., Schumacher, F. R., Gong, J., Harrison, T. A., Huyghe, J. R., Qu, C., Melas, M., Van Den Berg, D. J., Wang, H., Tring, S., Plummer, S. J., Albanes, D., Alonso, M. H., Amos, C. I., Anton, K., Aragaki, A. K., Arndt, V., Barry, E. L., Berndt, S. I. 及其他30, Bezieau, S., Bien, S., Bloomer, A., Boehm, J., Boutron-Ruault, M. C., Brenner, H., Brezina, S., Buchanan, D. D., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castelao, J. E., Chan, A. T., Chang-Claude, J., Chanock, S. J., Cheng, I., Cheng, Y. W., Chin, L. S., Church, J. M., Church, T., Coetzee, G. A., Cotterchio, M., Cruz Correa, M., Curtis, K. R., Duggan, D., Lin, Y., Liu, Y. R., Yen, Y. & Hsu, L., 二月 1 2019, 於 : Journal of the National Cancer Institute. 111, 2, p. 146-157 12 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)
2017

Overexpression of uridine-cytidine kinase 2 correlates with breast cancer progression and poor prognosis

Shen, G., He, P., Mao, Y., Li, P., Luh, F., Ding, G., Liu, X. & Yen, Y., 六月 1 2017, 於 : Journal of Breast Cancer. 20, 2, p. 132-141 10 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
2018

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Dai, Y., Wang, C., Chiu, L. Y., Abbasi, K., Tolbert, B. S., Sauvé, G., Yen, Y. & Liu, C. C., 十月 15 2018, 於 : Biosensors and Bioelectronics. 117, p. 60-67 8 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)
8 引文 斯高帕斯(Scopus)

Web-based platform vs genetic counselors in educating patients about carrier results from exome sequencing

Yen, Y. & Luh, F., 七月 1 2018, 於 : JAMA Internal Medicine. 178, 7, p. 998-999 2 p.

研究成果: 雜誌貢獻快報

1 引文 斯高帕斯(Scopus)
2016

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., 四月 27 2016, 於 : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2017

Does aspirin use reduce the risk for cancer?

Usman, I., Yang, H. C., Jian, W. S., Yen, Y. & Li, Y. C., 二月 1 2017, 於 : Journal of Investigative Medicine. 65, 2, p. 391-392 2 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2019

Does long-term use of antidiabetic drugs changes cancer risk?

Liu, Y. C., Nguyen, P. A., Humayun, A., Chien, S. C., Yang, H. C., Asdary, R. N., Syed-Abdul, S., Hsu, M. H., Moldovan, M., Yen, Y., Li, Y. C., Jian, W. S. & Iqbal, U., 十月 1 2019, 於 : Medicine (United States). 98, 40, p. e17461 e17461.

研究成果: 雜誌貢獻文章

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2 引文 斯高帕斯(Scopus)
2018

A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma

El-Khoueiry, A. B., O’Donnell, R., Semrad, T. J., Mack, P., Blanchard, S., Bahary, N., Jiang, Y., Yen, Y., Wright, J., Chen, H., Lenz, H. J. & Gandara, D. R., 五月 1 2018, 於 : Cancer Chemotherapy and Pharmacology. 81, 5, p. 957-963 7 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)
2019

Randomized trial of oral cyclophosphamide versus oral cyclophosphamide with celecoxib for recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer

Gupta, R., Cristea, M., Frankel, P., Ruel, C., Chen, C., Wang, Y., Morgan, R., Leong, L., Chow, W., Koczywas, M., Koehler, S., Lim, D., Luu, T., Martel, C., McNamara, M., Somlo, G., Twardowski, P., Yen, Y., Idorenyi, A., Raechelle, T. 及其他2, Carroll, M. & Chung, V., 一月 1 2019, 於 : Cancer Treatment and Research Communications. 21, 100155.

研究成果: 雜誌貢獻文章

2020

Cybersecurity in Science and Medicine: Threats and Challenges

Luh, F. & Yen, Y., 2020, (接受/付印) 於 : Trends in Biotechnology.

研究成果: 雜誌貢獻簡短的問卷調查

2019

Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer

Lu, H., Wang, C., Xue, L., Zhang, Q., Luh, F., Wang, J., Lin, T. G., Yen, Y. & Liu, X., 一月 1 2019, 於 : Journal of Oncology. 2019, 2316237.

研究成果: 雜誌貢獻文章

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2 引文 斯高帕斯(Scopus)
2016

A phase I pharmacodynamic study of GTI-2040, an antisense oligonucleotide against ribonuclotide reductase, in acute leukemias: a California Cancer Consortium study

Kirschbaum, M. H., Frankel, P., Synold, T. W., Xie, Z., Yen, Y., Popplewell, L., Chen, R., Aljitawi, O., Tuscano, J. M., Chan, K. K. & Newman, E. M., 十月 2 2016, 於 : Leukemia and Lymphoma. 57, 10, p. 2307-2314 8 p.

研究成果: 雜誌貢獻文章

The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells

Chen, C. W., Tsao, N., Huang, L. Y., Yen, Y., Liu, X., Lehman, C., Wang, Y. H., Tseng, M. C., Chen, Y. J., Ho, Y. C., Chen, C. F. & Chang, Z. F., 八月 2 2016, 於 : Cell Reports. 16, 5, p. 1287-1299 13 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker

Zhang, L., Chen, Z., Xue, D., Zhang, Q., Liu, X., Luh, F., Hong, L., Zhang, H., Pan, F., Liu, Y., Chu, P., Zheng, S., Lou, G. & Yen, Y., 十一月 1 2016, 於 : Oncology Reports. 36, 5, p. 2489-2500 12 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

Research of StemBios cell therapy on dental implants containing nanostructured surfaces: Biomechanical behaviors, microstructural characteristics, and clinical trial

Ou, K. L., Weng, C. C., Wu, C. C., Lin, Y. H., Chiang, H. J., Yang, T. S., Wang, J., Yen, Y., Cheng, H. Y. & Sugiatno, E., 二月 1 2016, 於 : Implant Dentistry. 25, 1, p. 63-73 11 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)
2017

Mechanism and clinical properties of stembios cell therapy: Induction of early osseointegration in novel dental implants

Weng, C. C., Ou, K. L., Wu, C. Y., Huang, Y. H., Wang, J., Yen, Y., Cheng, H. Y. & Lin, Y. H., 2017, 於 : International Journal of Oral and Maxillofacial Implants. 32, 1, p. e47-e54

研究成果: 雜誌貢獻文章

2019

Chicken-Derived Humanized Antibody Targeting a Novel Epitope F2pep of Fibroblast Growth Factor Receptor 2: Potential Cancer Therapeutic Agent

Tsai, K. C., Chang, C. D., Cheng, M. H., Lin, T. Y., Lo, Y. N., Yang, T. W., Chang, F. L., Chiang, C. W., Lee, Y. C. & Yen, Y., 一月 31 2019, 於 : ACS Omega. 4, 1, p. 2387-2397 11 p.

研究成果: 雜誌貢獻文章

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1 引文 斯高帕斯(Scopus)
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2018

The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes

Wang, Y. C., Chang, K. C., Lin, B. W., Lee, J. C., Lai, C. H., Lin, L. J., Yen, Y., Lin, C. S., Yang, S. J., Lin, P. C., Lee, C. T. & Hung, L. Y., 六月 1 2018, 於 : Experimental and Molecular Medicine. 50, 6, p. 70 70.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
2019

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers

Chen, Y. F., Wang, Y. H., Lei, C. S., Changou, C. A., Davis, M. E. & Yen, Y., 十月 23 2019, 於 : Journal of Biomedical Science. 26, 1, 1 p., 85.

研究成果: 雜誌貢獻回顧型文獻

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3 引文 斯高帕斯(Scopus)
2017
2 引文 斯高帕斯(Scopus)
2020
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1 引文 斯高帕斯(Scopus)
2016
23 引文 斯高帕斯(Scopus)
11 引文 斯高帕斯(Scopus)
2017
5 引文 斯高帕斯(Scopus)
2019

Rrm2b deletion causes mitochondrial metabolic defects in renal tubules

Chen, Y. F., Lin, I. H., Guo, Y. R., Chiu, W. J., Wu, M. S., Jia, W. & Yen, Y., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 1 p., 13238.

研究成果: 雜誌貢獻文章

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1 引文 斯高帕斯(Scopus)
2018

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., 三月 1 2018, 於 : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction

Cheng, C. T., Qi, Y., Wang, Y. C., Chi, K. K., Chung, Y., Ouyang, C., Chen, Y. R., Oh, M. E., Sheng, X., Tang, Y., Liu, Y. R., Lin, H. H., Kuo, C. Y., Schones, D., Vidal, C. M., Chu, J. C. Y., Wang, H. J., Chen, Y. H., Miller, K. M., Chu, P. 及其他4, Yen, Y., Jiang, L., Kung, H. J. & Ann, D. K., 十二月 1 2018, 於 : Communications Biology. 1, 1, 178.

研究成果: 雜誌貢獻文章

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12 引文 斯高帕斯(Scopus)

Global DNA methylation analysis reveals miR-214-3p contributes to cisplatin resistance in pediatric intracranial nongerminomatous malignant germ cell tumors

Hsieh, T. H., Liu, Y. R., Chang, T. Y., Liang, M. L., Chen, H. H., Wang, H. W., Yen, Y. & Wong, T-T., 三月 27 2018, 於 : Neuro-Oncology. 20, 4, p. 519-530 12 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)
2016

Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Yang, S. H., Lin, H. Y., Changou, C. A., Chen, C. H., Liu, Y. R., Wang, J., Jiang, X., Luh, F. & Yen, Y., 2016, 於 : Oncotarget. 7, 1, p. 362-373 12 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2018

Tyrosine kinase inhibitors for advanced or metastatic thyroid cancer: a meta-analysis of randomized controlled trials

Liu, J. W., Chen, C., Loh, E. W., Chu, C. C., Wang, M. Y., Ouyang, H. J., Chang, Y. T., Zhuang, W. Z., Chou, C. W., Huang, D. J., Lee, C. H., Yen, Y. & Tam, K. W., 2018, 於 : Current Medical Research and Opinion. p. 1-9 9 p.

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)
2017
7 引文 斯高帕斯(Scopus)
2016

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol

Sun, G., Cheng, Y. W., Lai, L., Huang, T. C., Wang, J., Wu, X., Wang, Y., Huang, Y., Wang, J., Zhang, K., Hu, S., Yang, J. R. & Yen, Y., 2016, 於 : Oncotarget. 7, 4, p. 3857-3872 16 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)
2020

Astragalus membranaceus-Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors

Chang, F. L., Tsai, K. C., Lin, T. Y., Yang, T. W., Lo, Y. N., Chen, W. C., Chang, J. H., Lu, M. K., Chiou, C. T., Chen, P. H., Yen, Y., Pan, S. L. & Lee, Y. C., 一月 1 2020, 於 : BioMed Research International. 2020, 3415471.

研究成果: 雜誌貢獻文章

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4 引文 斯高帕斯(Scopus)
2017

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

Huang, Y. J., Yang, C. K., Wei, P. L., Huynh, T. T., Whang-Peng, J., Meng, T. C., Hsiao, M., Tzeng, Y. M., Wu, A. T. & Yen, Y., 二月 28 2017, 於 : Journal of hematology & oncology. 10, 1, p. 60 1 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)
2020

Upregulation of protein synthesis and proteasome degradation confers sensitivity to proteasome inhibitor bortezomib in myc-atypical teratoid/rhabdoid tumors

Tran, H. M., Wu, K. S., Sung, S. Y., Changou, C. A., Hsieh, T. H., Liu, Y. R., Liu, Y. L., Tsai, M. L., Lee, H. L., Hsieh, K. L. C., Huang, W. C., Liang, M. L., Chen, H. H., Lee, Y. Y., Lin, S. C., Ho, D. M. T., Chang, F. C., Chao, M. E., Chen, W., Chu, S. S. 及其他4, Yu, A. L., Yen, Y., Chang, C. C. & Wong, T. T., 三月 22 2020, 於 : Cancers. 12, 3, 752.

研究成果: 雜誌貢獻文章

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2019
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2 引文 斯高帕斯(Scopus)
2018

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., 九月 15 2018, 於 : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

研究成果: 雜誌貢獻文章

51 引文 斯高帕斯(Scopus)
2019

DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Chen, C. W., Li, Y., Hu, S., Zhou, W., Meng, Y., Li, Z., Zhang, Y., Sun, J., Bo, Z., DePamphilis, M. L., Yen, Y., Han, Z. & Zhu, W., 三月 2019, 於 : Oncogene. 38, 13, p. 2364-2379 16 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2016

Precision Medicine and Pancreatic Cancer

Farrell, J. J., Moughan, J., Wong, J. L., Regine, W. F., Schaefer, P., Benson, A. B., Macdonald, J. S., Liu, X., Yen, Y., Lai, R., Zheng, Z., Bepler, G., Guha, C. & Elsaleh, H., 十一月 1 2016, 於 : Pancreas. 45, 10, p. 1485-1493 9 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer

Wu, J., Zhang, S., Shan, J., Hu, Z., Liu, X., Chen, L., Ren, X., Yao, L., Sheng, H., Li, L., Ann, D., Yen, Y., Wang, J. & Wang, X., 七月 1 2016, 於 : Cancer Letters. 376, 2, p. 284-292 9 p.

研究成果: 雜誌貢獻文章

43 引文 斯高帕斯(Scopus)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Kuo, M. L., Lee, M. B. E., Tang, M., Den Besten, W., Hu, S., Sweredoski, M. J., Hess, S., Chou, C. M., Changou, C. A., Su, M., Jia, W., Su, L. & Yen, Y., 一月 6 2016, 於 : Scientific Reports. 6, 18846.

研究成果: 雜誌貢獻文章

26 引文 斯高帕斯(Scopus)
2019

Cancers in Taiwan: Practical insight from epidemiology, treatments, biomarkers, and cost

Kuo, C. N., Liao, Y. M., Kuo, L. N., Tsai, H. J., Chang, W. C. & Yen, Y., 一月 1 2019, (接受/付印) 於 : Journal of the Formosan Medical Association.

研究成果: 雜誌貢獻回顧型文獻

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5 引文 斯高帕斯(Scopus)