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出版年份

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

作者

  • Yun Yen
2012

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth

Rahman, M. A., Amin, A. R. M. R., Wang, X., Zuckerman, J. E., Choi, C. H. J., Zhou, B., Wang, D., Nannapaneni, S., Koenig, L., Chen, Z., Chen, Z. G., Yen, Y., Davis, M. E. & Shin, D. M., 五月 10 2012, 於 : Journal of Controlled Release. 159, 3, p. 384-392 9 p.

研究成果: 雜誌貢獻文章

60 引文 斯高帕斯(Scopus)
2013

Targeting ribonucleotide reductase for cancer therapy

Shao, J., Liu, X., Zhu, L. & Yen, Y., 十二月 1 2013, 於 : Expert Opinion on Therapeutic Targets. 17, 12, p. 1423-1437 15 p.

研究成果: 雜誌貢獻回顧型文獻

40 引文 斯高帕斯(Scopus)
2014

Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers

Zhang, H., Liu, X., Warden, C. D., Huang, Y., Loera, S., Xue, L., Zhang, S., Chu, P., Zheng, S. & Yen, Y., 九月 11 2014, 於 : BMC Cancer. 14, 1, 664.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)
2012

Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia

Lin, H. H., Li, X., Chen, J. L., Sun, X., Cooper, F. N., Chen, Y. R., Zhang, W., Chung, Y., Li, A., Cheng, C. T., Yang, L., Deng, X. T., Liu, X., Yen, Y., Johnson, D. L., Shih, H. M., Yang, A. & Ann, D. K., 三月 1 2012, 於 : Molecular and Cellular Biology. 32, 6, p. 1124-1138 15 p.

研究成果: 雜誌貢獻文章

26 引文 斯高帕斯(Scopus)
2011
1 引文 斯高帕斯(Scopus)
2013

Characterization of Two Novel Cell Lines with Distinct Heterogeneity Derived from a Single Human Bile Duct Carcinoma

Wang, J., Li, L., Zhang, K., Yu, Y., Li, B., Li, J., Yan, Z., Hu, Z., Yen, Y., Wu, M., Jiang, X. & Qian, Q., 一月 30 2013, 於 : PLoS One. 8, 1, e54377.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2011

A bias-reducing strategy in profiling small RNAs using Solexa

Sun, G., Wu, X., Wang, J., Li, H., Li, X., Gao, H., Rossi, J. & Yen, Y., 十二月 1 2011, 於 : RNA. 17, 12, p. 2256-2262 7 p.

研究成果: 雜誌貢獻文章

30 引文 斯高帕斯(Scopus)
2012

Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NFκB signaling, and synergizes with an ERK inhibitor

Yang, F., Jove, V., Chang, S., Hedvat, M., Liu, L., Buettner, R., Tian, Y., Scuto, A., Wen, W., Yip, M. L. R., Van Meter, T. E., Yen, Y. & Jove, R., 四月 1 2012, 於 : Cancer Biology and Therapy. 13, 6, p. 349-357 9 p.

研究成果: 雜誌貢獻文章

26 引文 斯高帕斯(Scopus)
2013

A phase II study of hydroxyurea combined with gemcitabine in patients with head and neck squamous carcinoma and gene expression profiles correlated to poor response

Zhang, K., Kim, C., Wu, X., Loera, S., Wang, Y., Chu, P., Lim, D., Shibata, S. & Yen, Y., 二月 27 2013, 於 : Head and Neck Oncology. 5, 3, 3.

研究成果: 雜誌貢獻文章

2012

Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers

Hu, H., Zhang, H., Ge, W., Liu, X., Loera, S., Chu, P., Chen, H., Peng, J., Zhou, L., Yu, S., Yuan, Y., Zhang, S., Lai, L., Yen, Y. & Zheng, S., 十月 1 2012, 於 : Clinical Cancer Research. 18, 19, p. 5438-5448 11 p.

研究成果: 雜誌貢獻文章

27 引文 斯高帕斯(Scopus)
2014

The role of peroxiredoxin II in chemoresistance of breast cancer cells

Wang, T., Diaz, A. J. G. & Yen, Y., 2014, 於 : Breast Cancer: Targets and Therapy. 6, p. 73-80 8 p.

研究成果: 雜誌貢獻文章

17 引文 斯高帕斯(Scopus)
2011

Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors

Gaur, S., Chen, L., Yang, L., Wu, X., Un, F. & Yen, Y., 十二月 1 2011, 於 : Cancer Letters. 311, 1, p. 20-28 9 p.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)

Overexpression of HMGA2 promotes metastasis and impacts survival of colorectal cancers

Wang, X., Liu, X., Li, A. Y. J., Chen, L., Lai, L., Lin, H. H., Hu, S., Yao, L., Peng, J., Loera, S., Xue, L., Zhou, B., Zhou, L., Zheng, S., Chu, P., Zhang, S., Ann, D. K. & Yen, Y., 四月 15 2011, 於 : Clinical Cancer Research. 17, 8, p. 2570-2580 11 p.

研究成果: 雜誌貢獻文章

123 引文 斯高帕斯(Scopus)
2013

Enhanced radiation response in radioresistant MCF-7 cells by targeting peroxiredoxin II

Diaz, A. J. G., Tamae, D., Yen, Y., Li, J. & Wang, T., 十月 11 2013, 於 : Breast Cancer: Targets and Therapy. 5, p. 87-101 15 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
2019

Randomized trial of oral cyclophosphamide versus oral cyclophosphamide with celecoxib for recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer

Gupta, R., Cristea, M., Frankel, P., Ruel, C., Chen, C., Wang, Y., Morgan, R., Leong, L., Chow, W., Koczywas, M., Koehler, S., Lim, D., Luu, T., Martel, C., McNamara, M., Somlo, G., Twardowski, P., Yen, Y., Idorenyi, A., Raechelle, T. 及其他2, Carroll, M. & Chung, V., 一月 1 2019, 於 : Cancer Treatment and Research Communications. 21, 100155.

研究成果: 雜誌貢獻文章

2012

ROS1 as a 'druggable' receptor tyrosine kinase: Lessons learned from inhibiting the ALK pathway

Ou, S. H. I., Tan, J., Yen, Y. & Soo, R. A., 四月 2012, 於 : Expert Review of Anticancer Therapy. 12, 4, p. 447-456 10 p.

研究成果: 雜誌貢獻文章

92 引文 斯高帕斯(Scopus)
2014

Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro

Wang, J., Guo, X., Lui, M., Chu, P. J., Yoo, J., Chang, M. & Yen, Y., 一月 17 2014, 於 : PLoS One. 9, 1, e85112.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2012

A dose escalation and pharmacodynamic study of triapine and radiation in patients with locally advanced pancreas cancer

Martin, L. K., Grecula, J., Jia, G., Wei, L., Yang, X., Otterson, G. A., Wu, X., Harper, E., Kefauver, C., Zhou, B. S., Yen, Y., Bloomston, M., Knopp, M., Ivy, S. P., Grever, M. & Bekaii-Saab, T., 十一月 15 2012, 於 : International Journal of Radiation Oncology Biology Physics. 84, 4

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2014

A distinct metabolic signature of human colorectal cancer with prognostic potential

Qiu, Y., Cai, G., Zhou, B., Li, D., Zhao, A., Xie, G., Li, H., Cai, S., Xie, D., Huang, C., Ge, W., Zhou, Z., Xu, L. X., Jia, W., Zheng, S., Yen, Y. & Jia, W., 四月 15 2014, 於 : Clinical Cancer Research. 20, 8, p. 2136-2146 11 p.

研究成果: 雜誌貢獻文章

76 引文 斯高帕斯(Scopus)

Hepatobiliary cancers, version 2.2014

Benson, A. B., D'Angelica, M. I., Abrams, T. A., Are, C., Bloomston, P. M., Chang, D. T., Clary, B. M., Covey, A. M., Ensminger, W. D., Iyer, R., Kelley, R. K., Linehan, D., Malafa, M. P., Meranze, S. G., Park, J. O., Pawlik, T., Posey, J. A., Scaife, C., Schefter, T., Sigurdson, E. R. 及其他8, Tian, G. G., Vauthey, J. N., Venook, A. P., Yen, Y., Zhu, A. X., Hoffmann, K. G., McMillian, N. R. & Sundar, H., 八月 1 2014, 於 : JNCCN Journal of the National Comprehensive Cancer Network. 12, 8, p. 1152-1182 31 p.

研究成果: 雜誌貢獻回顧型文獻

41 引文 斯高帕斯(Scopus)
2013

Mass spectrometry-based quantitative metabolomics revealed a distinct lipid profile in breast cancer patients

Qiu, Y., Zhou, B., Su, M., Baxter, S., Zheng, X., Zhao, X., Yen, Y. & Jia, W., 一月 1 2013, 於 : International Journal of Molecular Sciences. 14, 4, p. 8047-8061 15 p.

研究成果: 雜誌貢獻文章

54 引文 斯高帕斯(Scopus)
2014

Cancer-Secreted miR-105 destroys vascular endothelial barriers to promote metastasis

Zhou, W., Fong, M. Y., Min, Y., Somlo, G., Liu, L., Palomares, M. R., Yu, Y., Chow, A., O'Connor, S. T. F., Chin, A. R., Yen, Y., Wang, Y., Marcusson, E. G., Chu, P., Wu, J., Wu, X., Li, A. X., Li, Z., Gao, H., Ren, X. 及其他3, Boldin, M. P., Lin, P. C. & Wang, S. E., 四月 14 2014, 於 : Cancer Cell. 25, 4, p. 501-515 15 p.

研究成果: 雜誌貢獻文章

565 引文 斯高帕斯(Scopus)
2012

Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression

Liu, N., Meng, Z., Lou, G., Zhou, W., Wang, X., Zhang, Y., Zhang, L., Liu, X., Yen, Y., Lai, L., Forman, B. M., Xu, Z., Xu, R. & Huang, W., 五月 1 2012, 於 : Molecular Endocrinology. 26, 5, p. 775-785 11 p.

研究成果: 雜誌貢獻文章

66 引文 斯高帕斯(Scopus)

Γ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers

Fu, S., Yang, Y., Tirtha, D., Yen, Y., Zhou, B. S., Zhou, M. M., Ohlmeyer, M., Ko, E. C., Cagan, R., Rosenstein, B. S., Chen, S. H. & Kao, J., 六月 29 2012, 於 : PLoS One. 7, 6, e38465.

研究成果: 雜誌貢獻文章

19 引文 斯高帕斯(Scopus)
2019

DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Chen, C. W., Li, Y., Hu, S., Zhou, W., Meng, Y., Li, Z., Zhang, Y., Sun, J., Bo, Z., DePamphilis, M. L., Yen, Y., Han, Z. & Zhu, W., 三月 2019, 於 : Oncogene.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
2011

Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma

Chen, T., Xie, G., Wang, X., Fan, J., Qiu, Y., Zheng, X., Qi, X., Cao, Y., Su, M., Wang, X., Xu, L. X., Yen, Y., Liu, P. & Jia, W., 七月 1 2011, 於 : Molecular and Cellular Proteomics. 10, 7

研究成果: 雜誌貢獻文章

184 引文 斯高帕斯(Scopus)

The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival

Scuto, A., Krejci, P., Popplewell, L., Wu, J., Wang, Y., Kujawski, M., Kowolik, C., Xin, H., Chen, L., Wang, Y., Kretzner, L., Yu, H., Wilcox, W. R., Yen, Y., Forman, S. & Jove, R., 三月 2011, 於 : Leukemia. 25, 3, p. 538-550 13 p.

研究成果: 雜誌貢獻文章

87 引文 斯高帕斯(Scopus)
2020

Cybersecurity in Science and Medicine: Threats and Challenges

Luh, F. & Yen, Y., 2020, (接受/付印) 於 : Trends in Biotechnology.

研究成果: 雜誌貢獻簡短的問卷調查

2015

Correction: HP1β is a biomarker for breast cancer prognosis and PARP inhibitor therapy(PLoS ONE (2015) 10:3 (e0121207) 10.1371/journal.pone.0121207)

Lee, Y. H., Liu, X., Qiu, F., O'Connor, T. R., Yen, Y. & Ann, D. K., 四月 13 2015, 於 : PLoS One. 10, 4, 0124853.

研究成果: 雜誌貢獻評論/辯論

2014

Expression of glypican 3 enriches hepatocellular carcinoma development-related genes and associates with carcinogenesis in cirrhotic livers

Liu, X., Wang, S. K., Zhang, K., Zhang, H., Pan, Q., Liu, Z., Pan, H., Xue, L., Yen, Y. & Chu, P. G., 八月 20 2014, 於 : Carcinogenesis. 36, 2, p. 232-242 11 p.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)
2013

Chromosomal Instability Triggered by Rrm2b Loss Leads to IL-6 Secretion and Plasmacytic Neoplasms

Chang, L., Guo, R., Huang, Q. & Yen, Y., 五月 30 2013, 於 : Cell Reports. 3, 5, p. 1389-1397 9 p.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)

Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer

Wang, Q., Liu, X., Zhou, J., Huang, Y., Zhang, S., Shen, J., Loera, S., Yuan, X., Chen, W., Jin, M., Shibata, S., Liu, Y., Chu, P., Wang, L. & Yen, Y., 七月 29 2013, 於 : PLoS One. 8, 7, e70191.

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)
2015

Detection of lysyl oxidase-like 2 (LOXL2), a biomarker of metastasis from breast cancers using human blood samples

Janyasupab, M., Lee, Y. H., Zhang, Y., Liu, C. W., Cai, J., Popa, A., Samia, A. C., Wang, K. W., Xu, J., Hu, C. C., Wendt, M. K., Schiemann, B. J., Thompson, C. L., Yen, Y., Schiemann, W. P. & Liu, C. C., 八月 1 2015, 於 : Recent Patents on Biomarkers. 5, 2, p. 93-100 8 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2011

Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels

Kretzner, L., Scuto, A., Dino, P. M., Kowolik, C. M., Wu, J., Ventura, P., Jove, R., Forman, S. J., Yen, Y. & Kirschbaum, M. H., 六月 1 2011, 於 : Cancer Research. 71, 11, p. 3912-3920 9 p.

研究成果: 雜誌貢獻文章

78 引文 斯高帕斯(Scopus)
2013

A small-molecule blocking ribonucleotide reductase holoenzyme formation inhibits cancer cell growth and overcomes drug resistance

Zhou, B., Su, L., Hu, S., Hu, W., Yip, M. L. R., Wu, J., Gaur, S., Smith, D. L., Yuan, Y. C., Synold, T. W., Horne, D. & Yen, Y., 十一月 1 2013, 於 : Cancer Research. 73, 21, p. 6484-6493 10 p.

研究成果: 雜誌貢獻文章

33 引文 斯高帕斯(Scopus)

Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma

Zhang, K., Chu, K., Wu, X., Gao, H., Wang, J., Yuan, Y. C., Loera, S., Ho, K., Wang, Y., Chow, W., Un, F., Chu, P. & Yen, Y., 一月 15 2013, 於 : Cancer Research. 73, 4, p. 1298-1307 10 p.

研究成果: 雜誌貢獻文章

54 引文 斯高帕斯(Scopus)
2016

Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer

Wu, J., Zhang, S., Shan, J., Hu, Z., Liu, X., Chen, L., Ren, X., Yao, L., Sheng, H., Li, L., Ann, D., Yen, Y., Wang, J. & Wang, X., 七月 1 2016, 於 : Cancer Letters. 376, 2, p. 284-292 9 p.

研究成果: 雜誌貢獻文章

42 引文 斯高帕斯(Scopus)
2015

KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination

Chen, H. Y., Hu, J. Y., Chen, T. H., Lin, Y. C., Liu, X., Lin, M. Y., Lang, Y. D., Yen, Y. & Chen, R. H., 十月 1 2015, 於 : Oncogene. 34, 40, p. 5141-5151 11 p.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)
2013

MicroRNA-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through nuclear factor kappa B pathways

Zhang, L., Yang, L., Liu, X., Chen, W., Chang, L., Chen, L., Loera, S., Chu, P., Huang, W. C., Liu, Y. R. & Yen, Y., 五月 1 2013, 於 : Hepatology. 57, 5, p. 1919-1930 12 p.

研究成果: 雜誌貢獻文章

44 引文 斯高帕斯(Scopus)
2011

FZD7 has a critical role in cell proliferation in triple negative breast cancer

Yang, L., Wu, X., Wang, Y., Zhang, K., Wu, J., Yuan, Y. C., Deng, X., Chen, L., Kim, C. C. H., Lau, S., Somlo, G. & Yen, Y., 十月 27 2011, 於 : Oncogene. 30, 43, p. 4437-4446 10 p.

研究成果: 雜誌貢獻文章

163 引文 斯高帕斯(Scopus)
2016
23 引文 斯高帕斯(Scopus)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Kuo, M. L., Lee, M. B. E., Tang, M., Den Besten, W., Hu, S., Sweredoski, M. J., Hess, S., Chou, C. M., Changou, C. A., Su, M., Jia, W., Su, L. & Yen, Y., 一月 6 2016, 於 : Scientific Reports. 6, 18846.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)
2020

Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats

Yang, Y. C. S. H., Chang, H. W., Lin, I. H., Chien, L. N., Wu, M. J., Liu, Y. R., Chu, P. G., Xie, G., Dong, F., Jia, W., Chang, V. H. S. & Yen, Y., 十二月 1 2020, 於 : Scientific Reports. 10, 1, 866.

研究成果: 雜誌貢獻文章

開啟存取
1 引文 斯高帕斯(Scopus)
2014

Reciprocal regulation of autophagy and dNTP pools in human cancer cells

Chen, W., Zhang, L., Zhang, K., Zhou, B., Kuo, M. L., Hu, S., Chen, L., Tang, M., Chen, Y. R., Yang, L., Ann, D. K. & Yen, Y., 一月 1 2014, 於 : Autophagy. 10, 7, p. 1272-1284 13 p.

研究成果: 雜誌貢獻文章

27 引文 斯高帕斯(Scopus)

Frequent overexpression of HMGA2 in human atypical teratoid/rhabdoid tumor and its correlation with let-7a3/let-7b miRNA

Zhang, K., Gao, H., Wu, X., Wang, J., Zhou, W., Sun, G., Wang, J., Wang, Y., Mu, B., Kim, C., Chu, P., Ho, D. M., Ann, D. K., Wong, T. T. & Yen, Y., 2014, 於 : Clinical Cancer Research. 20, 5, p. 1179-1189 11 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)
2018

Tyrosine kinase inhibitors for advanced or metastatic thyroid cancer: a meta-analysis of randomized controlled trials

Liu, J. W., Chen, C., Loh, E. W., Chu, C. C., Wang, M. Y., Ouyang, H. J., Chang, Y. T., Zhuang, W. Z., Chou, C. W., Huang, D. J., Lee, C. H., Yen, Y. & Tam, K. W., 2018, 於 : Current Medical Research and Opinion. p. 1-9 9 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2019

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Schmit, S. L., Edlund, C. K., Schumacher, F. R., Gong, J., Harrison, T. A., Huyghe, J. R., Qu, C., Melas, M., Van Den Berg, D. J., Wang, H., Tring, S., Plummer, S. J., Albanes, D., Alonso, M. H., Amos, C. I., Anton, K., Aragaki, A. K., Arndt, V., Barry, E. L., Berndt, S. I. 及其他30, Bezieau, S., Bien, S., Bloomer, A., Boehm, J., Boutron-Ruault, M. C., Brenner, H., Brezina, S., Buchanan, D. D., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castelao, J. E., Chan, A. T., Chang-Claude, J., Chanock, S. J., Cheng, I., Cheng, Y. W., Chin, L. S., Church, J. M., Church, T., Coetzee, G. A., Cotterchio, M., Cruz Correa, M., Curtis, K. R., Duggan, D., Lin, Y., Liu, Y. R., Yen, Y. & Hsu, L., 二月 1 2019, 於 : Journal of the National Cancer Institute. 111, 2, p. 146-157 12 p.

研究成果: 雜誌貢獻文章

24 引文 斯高帕斯(Scopus)
2018

Phase IB trial of ixabepilone and vorinostat in metastatic breast cancer

Luu, T., Kim, K. P., Blanchard, S., Anyang, B., Hurria, A., Yang, L., Beumer, J. H., Somlo, G. & Yen, Y., 一月 1 2018, 於 : Breast Cancer Research and Treatment. 167, 2, p. 469-478 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2014

Cancer: Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells

Qiu, F., Chen, Y. R., Liu, X., Chu, C. Y., Shen, L. J., Xu, J., Gaur, S., Forman, H. J., Zhang, H., Zheng, S., Yen, Y., Huang, J., Kung, H. J. & Ann, D. K., 四月 1 2014, 於 : Science Signaling. 7, 319

研究成果: 雜誌貢獻文章

69 引文 斯高帕斯(Scopus)