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出版年份

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

作者

  • Yun Yen
2012

Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer

Gaur, S., Chen, L., Yen, T., Wang, Y., Zhou, B., Davis, M. & Yen, Y., 七月 1 2012, 於 : Nanomedicine: Nanotechnology, Biology, and Medicine. 8, 5, p. 721-730 10 p.

研究成果: 雜誌貢獻文章

41 引文 斯高帕斯(Scopus)
2011

Mechanistic control of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) splice isoforms by the heterogeneous nuclear ribonuclear proteins hnRNP L, hnRNP A1, and hnRNP M

Dery, K. J., Gaur, S., Gencheva, M., Yen, Y., Shively, J. E. & Gaur, R. K., 五月 6 2011, 於 : Journal of Biological Chemistry. 286, 18, p. 16039-16051 13 p.

研究成果: 雜誌貢獻文章

32 引文 斯高帕斯(Scopus)

Mammalian target of rapamycin and head and neck squamous cell carcinoma

Liao, Y. M., Kim, C. & Yen, Y., 四月 26 2011, 於 : Head and Neck Oncology. 3, 1, 22.

研究成果: 雜誌貢獻回顧型文獻

22 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)
2016

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells

Chen, Y. R., Tsou, B., Hu, S., Ma, H., Liu, X., Yen, Y. & Ann, D. K., 一月 1 2016, 於 : Oncotarget. 7, 2, p. 1984-1999 16 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)
2011

An overview of the rare parotid gland cancer

Ho, K., Lin, H., Ann, D. K., Chu, P. G. & Yen, Y., 九月 21 2011, 於 : Head and Neck Oncology. 3, 1, 40.

研究成果: 雜誌貢獻回顧型文獻

37 引文 斯高帕斯(Scopus)
2013

A small-molecule blocking ribonucleotide reductase holoenzyme formation inhibits cancer cell growth and overcomes drug resistance

Zhou, B., Su, L., Hu, S., Hu, W., Yip, M. L. R., Wu, J., Gaur, S., Smith, D. L., Yuan, Y. C., Synold, T. W., Horne, D. & Yen, Y., 十一月 1 2013, 於 : Cancer Research. 73, 21, p. 6484-6493 10 p.

研究成果: 雜誌貢獻文章

35 引文 斯高帕斯(Scopus)
2012

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth

Rahman, M. A., Amin, A. R. M. R., Wang, X., Zuckerman, J. E., Choi, C. H. J., Zhou, B., Wang, D., Nannapaneni, S., Koenig, L., Chen, Z., Chen, Z. G., Yen, Y., Davis, M. E. & Shin, D. M., 五月 10 2012, 於 : Journal of Controlled Release. 159, 3, p. 384-392 9 p.

研究成果: 雜誌貢獻文章

60 引文 斯高帕斯(Scopus)
2015

Detection and phenotyping of circulating tumor cells in high-risk localized prostate cancer

Pal, S. K., He, M., Wilson, T., Liu, X., Zhang, K., Carmichael, C., Torres, A., Hernandez, S., Lau, C., Agarwal, N., Kawachi, M., Yen, Y. & Jones, J. O., 四月 1 2015, 於 : Clinical Genitourinary Cancer. 13, 2, p. 130-136 7 p.

研究成果: 雜誌貢獻文章

31 引文 斯高帕斯(Scopus)
2014

MiR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis

Fu, X., Meng, Z., Liang, W., Tian, Y., Wang, X., Han, W., Lou, G., Wang, X., Lou, F., Yen, Y., Yu, H., Jove, R. & Huang, W., 八月 21 2014, 於 : Oncogene. 33, 34, p. 4296-4306 11 p.

研究成果: 雜誌貢獻文章

78 引文 斯高帕斯(Scopus)
2016

Polymeric nanoparticles and cancer: Lessons learnt from CRLX101

Gritli, I., Garmey, E., Eliasof, S., Tellez, A., Davis, M. E. & Yun, Y., 2016, Privileged Scaffolds in Medicinal Chemistry: Design, Synthesis, Evaluation. 51 編輯 Royal Society of Chemistry, 卷 2016-January. p. 199-232 34 p. (RSC Drug Discovery Series; 卷 2016-January, 編號 51).

研究成果: 書貢獻/報告類型章節

3 引文 斯高帕斯(Scopus)
2011

Small interfering RNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines

Tiemann, K., Alluin, J. V., Honegger, A., Chomchan, P., Gaur, S., Yun, Y., Forman, S. J., Rossi, J. J. & Chen, R. W., 十一月 1 2011, 於 : Leukemia and Lymphoma. 52, 11, p. 2148-2154 7 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2015

Primary Cutaneous Anaplastic Large Cell Lymphoma With Positive ALK Expression and a Rapidly Progressive Cutaneous Nodule

Xue, D., Li, X., Ren, Y., Liu, Q., Yen, Y. & Xue, L., 六月 3 2015, 於 : International Journal of Surgical Pathology. 23, 4, p. 333-335 3 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2013

Targeting ribonucleotide reductase for cancer therapy

Shao, J., Liu, X., Zhu, L. & Yen, Y., 十二月 1 2013, 於 : Expert Opinion on Therapeutic Targets. 17, 12, p. 1423-1437 15 p.

研究成果: 雜誌貢獻回顧型文獻

41 引文 斯高帕斯(Scopus)
2011

Ribonucleotide reductase small subunit M2B prognoses better survival in colorectal cancer

Liu, X., Lai, L., Wang, X., Xue, L., Leora, S., Wu, J., Hu, S., Zhang, K., Kuo, M. L., Zhou, L., Zhang, H., Wang, Y., Wang, Y., Zhou, B., Nelson, R. A., Zheng, S., Zhang, S., Chu, P. & Yen, Y., 五月 1 2011, 於 : Cancer Research. 71, 9, p. 3202-3213 12 p.

研究成果: 雜誌貢獻文章

48 引文 斯高帕斯(Scopus)
2013

Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers

Liu, X., Zhang, H., Lai, L., Wang, X., Loera, S., Xue, L., He, H., Zhang, K., Hu, S., Huang, Y., Nelson, R. A., Zhou, B., Zhou, L., Chu, P., Zhang, S., Zheng, S. & Yen, Y., 五月 1 2013, 於 : Clinical Science. 124, 9, p. 567-578 12 p.

研究成果: 雜誌貢獻文章

48 引文 斯高帕斯(Scopus)
2012

ROS1 as a 'druggable' receptor tyrosine kinase: Lessons learned from inhibiting the ALK pathway

Ou, S. H. I., Tan, J., Yen, Y. & Soo, R. A., 四月 2012, 於 : Expert Review of Anticancer Therapy. 12, 4, p. 447-456 10 p.

研究成果: 雜誌貢獻文章

96 引文 斯高帕斯(Scopus)
2011

Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels

Kretzner, L., Scuto, A., Dino, P. M., Kowolik, C. M., Wu, J., Ventura, P., Jove, R., Forman, S. J., Yen, Y. & Kirschbaum, M. H., 六月 1 2011, 於 : Cancer Research. 71, 11, p. 3912-3920 9 p.

研究成果: 雜誌貢獻文章

78 引文 斯高帕斯(Scopus)
2012

Ribonucleotide reductase and non-small cell lung cancer

Hsu, N. Y., Lee, H., Cheng, Y. W. & Yen, Y., 一月 1 2012, 於 : Chinese Journal of Lung Cancer. 15, 11, p. 619-623 5 p.

研究成果: 雜誌貢獻文章

2013

Chromosomal Instability Triggered by Rrm2b Loss Leads to IL-6 Secretion and Plasmacytic Neoplasms

Chang, L., Guo, R., Huang, Q. & Yen, Y., 五月 30 2013, 於 : Cell Reports. 3, 5, p. 1389-1397 9 p.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)

Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca2+/calmodulin- dependent protein kinase II

Meng, Z., Li, T., Ma, X., Wang, X., Ness, C. V., Gan, Y., Zhou, H., Tang, J., Lou, G., Wang, Y., Wu, J., Yen, Y., Xu, R. & Huang, W., 十月 2013, 於 : Molecular Cancer Therapeutics. 12, 10, p. 2067-2077 11 p.

研究成果: 雜誌貢獻文章

36 引文 斯高帕斯(Scopus)
2016

CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing

Clark, A. J., Wiley, D. T., Zuckerman, J. E., Webster, P., Chao, J., Lin, J., Yen, Y. & Davis, M. E., 四月 5 2016, 於 : Proceedings of the National Academy of Sciences of the United States of America. 113, 14, p. 3850-3854 5 p.

研究成果: 雜誌貢獻文章

90 引文 斯高帕斯(Scopus)
2013

Identification of novel mutations of TP53, ALK and RET gene in metastatic thymic squamous cell carcinoma and its therapeutic implication

Hu, Z., Wang, J., Yao, T., Hong, R. L., Zhang, K., Gao, H., Wu, X., Li, J., Bai, C. & Yen, Y., 七月 1 2013, 於 : Lung Cancer. 81, 1, p. 27-31 5 p.

研究成果: 雜誌貢獻回顧型文獻

5 引文 斯高帕斯(Scopus)

Human papillomavirus and non-small cell lung cancer

Hsu, N. Y., Lee, H., Yen, Y. & Cheng, Y. W., 十一月 2013, 於 : Thoracic Cancer. 4, 4, p. 345-353 9 p.

研究成果: 雜誌貢獻回顧型文獻

6 引文 斯高帕斯(Scopus)
2015

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma

Wang, J., Zhang, K., Wang, J., Wu, X., Liu, X., Li, B., Zhu, Y., Yu, Y., Cheng, Q., Hu, Z., Guo, C., Hu, S., Mu, B., Tsai, C. H., Li, J., Smith, L., Yang, L., Liu, Q., Chu, P., Chang, V. 及其他4, Zhang, B., Wu, M., Jiang, X. & Yen, Y., 2015, 於 : Oncotarget. 6, 22, p. 18905-18920 16 p.

研究成果: 雜誌貢獻文章

24 引文 斯高帕斯(Scopus)
2014

Cancer: Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells

Qiu, F., Chen, Y. R., Liu, X., Chu, C. Y., Shen, L. J., Xu, J., Gaur, S., Forman, H. J., Zhang, H., Zheng, S., Yen, Y., Huang, J., Kung, H. J. & Ann, D. K., 四月 1 2014, 於 : Science Signaling. 7, 319

研究成果: 雜誌貢獻文章

72 引文 斯高帕斯(Scopus)
2018

Differences in silencing of mismatched targets by sliced versus diced siRNAs

Sun, G., Wang, J., Huang, Y., Yuan, C. W. Y., Zhang, K., Hu, S., Chen, L., Lin, R. J., Yen, Y. & Riggs, A. D., 一月 1 2018, 於 : Nucleic Acids Research. 46, 13, p. 6806-6822 17 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Ribonucleotide reductase subunit M2B deficiency leads to mitochondrial permeability transition pore opening and is associated with aggressive clinicopathologic manifestations of breast cancer

Xue, L., Liu, X., Wang, Q., Liu, C. Q., Chen, Y., Jia, W., Hsie, R., Chen, Y., Luh, F., Zheng, S. & Yen, Y., 一月 1 2018, 於 : American Journal of Translational Research. 10, 11, p. 3635-3649 15 p., AJTR0084684.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
2017

Overexpression of uridine-cytidine kinase 2 correlates with breast cancer progression and poor prognosis

Shen, G., He, P., Mao, Y., Li, P., Luh, F., Ding, G., Liu, X. & Yen, Y., 六月 1 2017, 於 : Journal of Breast Cancer. 20, 2, p. 132-141 10 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
2018

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Dai, Y., Wang, C., Chiu, L. Y., Abbasi, K., Tolbert, B. S., Sauvé, G., Yen, Y. & Liu, C. C., 十月 15 2018, 於 : Biosensors and Bioelectronics. 117, p. 60-67 8 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)
8 引文 斯高帕斯(Scopus)

Web-based platform vs genetic counselors in educating patients about carrier results from exome sequencing

Yen, Y. & Luh, F., 七月 1 2018, 於 : JAMA Internal Medicine. 178, 7, p. 998-999 2 p.

研究成果: 雜誌貢獻快報

1 引文 斯高帕斯(Scopus)
2014

Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients

Cho, E. C., Kuo, M. L., Liu, X., Yang, L., Hsieh, Y. C., Wang, J., Cheng, Y. & Yen, Y., 2014, 於 : Oncotarget. 5, 13, p. 4834-4844 11 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)
2015

RRM2B-mediated regulation of mitochondrial activity and inflammation under oxidative stress

Cho, E. C., Kuo, M. L., Cheng, J. H., Cheng, Y. C., Hsieh, Y. C., Liu, Y. R., Hsieh, R. H. & Yen, Y., 2015, 於 : Mediators of Inflammation. 2015, 287345.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)
16 引文 斯高帕斯(Scopus)
2011

Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and function in KB and PC-3 cancer cells

Wang, X., Liu, X., Xue, L., Zhang, K., Kuo, M. L., Hu, S., Zhou, B., Ann, D., Zhang, S. & Yen, Y., 六月 24 2011, 於 : Biochemical and Biophysical Research Communications. 410, 1, p. 102-107 6 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2014

Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview

Chang, C., Shiah, H-S., Hsu, N-Y., Huang, H. Y., Chu, J-S. & Yen, Y., 2014, 於 : Case Reports in Surgery.

研究成果: 雜誌貢獻文章

2015

KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination

Chen, H. Y., Hu, J. Y., Chen, T. H., Lin, Y. C., Liu, X., Lin, M. Y., Lang, Y. D., Yen, Y. & Chen, R. H., 十月 1 2015, 於 : Oncogene. 34, 40, p. 5141-5151 11 p.

研究成果: 雜誌貢獻文章

18 引文 斯高帕斯(Scopus)
2014

Pharmacodynamic and pharmacogenomic study of the nanoparticle conjugate of camptothecin CRLX101 for the treatment of cancer

Gaur, S., Wang, Y., Kretzner, L., Chen, L., Yen, T., Wu, X., Yuan, Y. C., Davis, M. & Yen, Y., 十月 1 2014, 於 : Nanomedicine: Nanotechnology, Biology, and Medicine. 10, 7, p. 1477-1486 10 p.

研究成果: 雜誌貢獻文章

40 引文 斯高帕斯(Scopus)
2019

Does long-term use of antidiabetic drugs changes cancer risk?

Liu, Y. C., Nguyen, P. A., Humayun, A., Chien, S. C., Yang, H. C., Asdary, R. N., Syed-Abdul, S., Hsu, M. H., Moldovan, M., Yen, Y., Li, Y. C., Jian, W. S. & Iqbal, U., 十月 1 2019, 於 : Medicine (United States). 98, 40, p. e17461 e17461.

研究成果: 雜誌貢獻文章

開啟存取
2 引文 斯高帕斯(Scopus)
2016

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., 四月 27 2016, 於 : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2011

The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival

Scuto, A., Krejci, P., Popplewell, L., Wu, J., Wang, Y., Kujawski, M., Kowolik, C., Xin, H., Chen, L., Wang, Y., Kretzner, L., Yu, H., Wilcox, W. R., Yen, Y., Forman, S. & Jove, R., 三月 2011, 於 : Leukemia. 25, 3, p. 538-550 13 p.

研究成果: 雜誌貢獻文章

88 引文 斯高帕斯(Scopus)
2014

Hepatobiliary cancers, version 2.2014

Benson, A. B., D'Angelica, M. I., Abrams, T. A., Are, C., Bloomston, P. M., Chang, D. T., Clary, B. M., Covey, A. M., Ensminger, W. D., Iyer, R., Kelley, R. K., Linehan, D., Malafa, M. P., Meranze, S. G., Park, J. O., Pawlik, T., Posey, J. A., Scaife, C., Schefter, T., Sigurdson, E. R. 及其他8, Tian, G. G., Vauthey, J. N., Venook, A. P., Yen, Y., Zhu, A. X., Hoffmann, K. G., McMillian, N. R. & Sundar, H., 八月 1 2014, 於 : JNCCN Journal of the National Comprehensive Cancer Network. 12, 8, p. 1152-1182 31 p.

研究成果: 雜誌貢獻回顧型文獻

44 引文 斯高帕斯(Scopus)
2012

Γ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers

Fu, S., Yang, Y., Tirtha, D., Yen, Y., Zhou, B. S., Zhou, M. M., Ohlmeyer, M., Ko, E. C., Cagan, R., Rosenstein, B. S., Chen, S. H. & Kao, J., 六月 29 2012, 於 : PLoS One. 7, 6, e38465.

研究成果: 雜誌貢獻文章

19 引文 斯高帕斯(Scopus)
2016
8 引文 斯高帕斯(Scopus)
2017
5 引文 斯高帕斯(Scopus)
2020
開啟存取
2018

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., 九月 15 2018, 於 : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

研究成果: 雜誌貢獻文章

51 引文 斯高帕斯(Scopus)
2017

Does aspirin use reduce the risk for cancer?

Usman, I., Yang, H. C., Jian, W. S., Yen, Y. & Li, Y. C., 二月 1 2017, 於 : Journal of Investigative Medicine. 65, 2, p. 391-392 2 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2018

A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma

El-Khoueiry, A. B., O’Donnell, R., Semrad, T. J., Mack, P., Blanchard, S., Bahary, N., Jiang, Y., Yen, Y., Wright, J., Chen, H., Lenz, H. J. & Gandara, D. R., 五月 1 2018, 於 : Cancer Chemotherapy and Pharmacology. 81, 5, p. 957-963 7 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)