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研究成果 1994 2019

篩選
文章
2013
8 引文 (Scopus)

Characterization of Two Novel Cell Lines with Distinct Heterogeneity Derived from a Single Human Bile Duct Carcinoma

Wang, J., Li, L., Zhang, K., Yu, Y., Li, B., Li, J., Yan, Z., Hu, Z., Yen, Y., Wu, M., Jiang, X. & Qian, Q., 一月 30 2013, 於 : PLoS One. 8, 1, e54377.

研究成果: 雜誌貢獻文章

bile ducts
Bile Ducts
Ducts
carcinoma
Cells
16 引文 (Scopus)

Chromosomal Instability Triggered by Rrm2b Loss Leads to IL-6 Secretion and Plasmacytic Neoplasms

Chang, L., Guo, R., Huang, Q. & Yen, Y., 五月 30 2013, 於 : Cell Reports. 3, 5, p. 1389-1397 9 p.

研究成果: 雜誌貢獻文章

Chromosomal Instability
Interleukin-6
DNA Damage
Plasma Cell Neoplasms
Deoxyribonucleotides
74 引文 (Scopus)

Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle

Eliasof, S., Lazarus, D., Peters, C. G., Case, R. I., Cole, R. O., Hwang, J., Schluep, T., Chao, J., Lin, J., Yen, Y., Han, H., Wiley, D. T., Zuckerman, J. E. & Davis, M. E., 九月 10 2013, 於 : Proceedings of the National Academy of Sciences of the United States of America. 110, 37, p. 15127-15132 6 p.

研究成果: 雜誌貢獻文章

Nanoparticles
Camptothecin
Clinical Trials
Polymers
Animal Models
12 引文 (Scopus)

Enhanced radiation response in radioresistant MCF-7 cells by targeting peroxiredoxin II

Diaz, A. J. G., Tamae, D., Yen, Y., Li, J. & Wang, T., 十月 11 2013, 於 : Breast Cancer: Targets and Therapy. 5, p. 87-101 15 p.

研究成果: 雜誌貢獻文章

Peroxiredoxins
MCF-7 Cells
RNA Interference
Radiation
Breast Neoplasms
26 引文 (Scopus)

Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy

Zhou, W., Chen, Y. W., Liu, X., Chu, P., Loria, S., Wang, Y., Yen, Y. & Chou, K. M., 十二月 20 2013, 於 : PLoS One. 8, 12, e83978.

研究成果: 雜誌貢獻文章

gemcitabine
Squamous Cell Neoplasms
cisplatin
Chemotherapy
Head and Neck Neoplasms
103 引文 (Scopus)

First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies

Weiss, G. J., Chao, J., Neidhart, J. D., Ramanathan, R. K., Bassett, D., Neidhart, J. A., Choi, C. H. J., Chow, W., Chung, V., Forman, S. J., Garmey, E., Hwang, J., Kalinoski, D. L., Koczywas, M., Longmate, J., Melton, R. J., Morgan, R., Oliver, J., Peterkin, J. J., Ryan, J. L. 及其他5, Schluep, T., Synold, T. W., Twardowski, P., Davis, M. E. & Yen, Y., 八月 1 2013, 於 : Investigational New Drugs. 31, 4, p. 986-1000 15 p.

研究成果: 雜誌貢獻文章

Camptothecin
Maximum Tolerated Dose
Neoplasms
Polymers
Pharmacokinetics
43 引文 (Scopus)

Mass spectrometry-based quantitative metabolomics revealed a distinct lipid profile in breast cancer patients

Qiu, Y., Zhou, B., Su, M., Baxter, S., Zheng, X., Zhao, X., Yen, Y. & Jia, W., 一月 1 2013, 於 : International Journal of Molecular Sciences. 14, 4, p. 8047-8061 15 p.

研究成果: 雜誌貢獻文章

Metabolomics
breast
Lipids
Mass spectrometry
lipids
42 引文 (Scopus)

MicroRNA-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through nuclear factor kappa B pathways

Zhang, L., Yang, L., Liu, X., Chen, W., Chang, L., Chen, L., Loera, S., Chu, P., Huang, W. C., Liu, Y. R. & Yen, Y., 五月 1 2013, 於 : Hepatology. 57, 5, p. 1919-1930 12 p.

研究成果: 雜誌貢獻文章

Transducin
NF-kappa B
MicroRNAs
Hepatocellular Carcinoma
Carcinogenesis
13 引文 (Scopus)

Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer

Wang, Q., Liu, X., Zhou, J., Huang, Y., Zhang, S., Shen, J., Loera, S., Yuan, X., Chen, W., Jin, M., Shibata, S., Liu, Y., Chu, P., Wang, L. & Yen, Y., 七月 29 2013, 於 : PLoS One. 8, 7, e70191.

研究成果: 雜誌貢獻文章

ribonucleotide reductase
Ribonucleotide Reductases
stomach neoplasms
Stomach Neoplasms
Modulation
41 引文 (Scopus)

Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers

Liu, X., Zhang, H., Lai, L., Wang, X., Loera, S., Xue, L., He, H., Zhang, K., Hu, S., Huang, Y., Nelson, R. A., Zhou, B., Zhou, L., Chu, P., Zhang, S., Zheng, S. & Yen, Y., 五月 1 2013, 於 : Clinical Science. 124, 9, p. 567-578 12 p.

研究成果: 雜誌貢獻文章

Colorectal Neoplasms
Biomarkers
Confidence Intervals
Aptitude
Multivariate Analysis
2012
9 引文 (Scopus)

A dose escalation and pharmacodynamic study of triapine and radiation in patients with locally advanced pancreas cancer

Martin, L. K., Grecula, J., Jia, G., Wei, L., Yang, X., Otterson, G. A., Wu, X., Harper, E., Kefauver, C., Zhou, B. S., Yen, Y., Bloomston, M., Knopp, M., Ivy, S. P., Grever, M. & Bekaii-Saab, T., 十一月 15 2012, 於 : International Journal of Radiation Oncology Biology Physics. 84, 4

研究成果: 雜誌貢獻文章

pancreas
Pancreatic Neoplasms
cancer
Radiation
dosage
20 引文 (Scopus)

A phase I and pharmacokinetic study of oral 3-aminopyridine-2- carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in the treatment of advanced-stage solid cancers: A California Cancer Consortium Study

Chao, J., Synold, T. W., Morgan, R. J., Kunos, C., Longmate, J., Lenz, H. J., Lim, D., Shibata, S., Chung, V., Stoller, R. G., Belani, C. P., Gandara, D. R., McNamara, M., Gitlitz, B. J., Lau, D. H., Ramalingam, S. S., Davies, A., Espinoza-Delgado, I., Newman, E. M. & Yen, Y., 三月 1 2012, 於 : Cancer Chemotherapy and Pharmacology. 69, 3, p. 835-843 9 p.

研究成果: 雜誌貢獻文章

Pharmacokinetics
Toxicity
Tumors
Maximum Tolerated Dose
Neoplasms
26 引文 (Scopus)

Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NFκB signaling, and synergizes with an ERK inhibitor

Yang, F., Jove, V., Chang, S., Hedvat, M., Liu, L., Buettner, R., Tian, Y., Scuto, A., Wen, W., Yip, M. L. R., Van Meter, T. E., Yen, Y. & Jove, R., 四月 1 2012, 於 : Cancer Biology and Therapy. 13, 6, p. 349-357 9 p.

研究成果: 雜誌貢獻文章

Medulloblastoma
Apoptosis
Growth
Proteasome Inhibitors
Apoptosis Regulatory Proteins
136 引文 (Scopus)

De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

Wu, X., Somlo, G., Yu, Y., Palomares, M. R., Li, A. X., Zhou, W., Chow, A., Yen, Y., Rossi, J. J., Gao, H., Wang, J., Yuan, Y. C., Frankel, P., Li, S., Ashing-Giwa, K. T., Sun, G., Wang, Y., Smith, R., Robinson, K., Ren, X. 及其他1, Wang, S. E., 三月 8 2012, 於 : Journal of Translational Medicine. 10, 1, 42.

研究成果: 雜誌貢獻文章

MicroRNAs
Biomarkers
Breast Neoplasms
Chemotherapy
Inflammatory Breast Neoplasms
17 引文 (Scopus)

Emerging role of autophagy during ischemia-hypoxia and reperfusion in hepatocellular carcinoma

Du, H., Yang, W., Chen, L., Shen, B., Peng, C., Li, H., Ann, D. K., Yen, Y. & Qiu, W., 六月 1 2012, 於 : International Journal of Oncology. 40, 6, p. 2049-2057 9 p.

研究成果: 雜誌貢獻文章

Autophagy
Reperfusion
Hepatocellular Carcinoma
Ischemia
Hep G2 Cells
59 引文 (Scopus)

Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression

Liu, N., Meng, Z., Lou, G., Zhou, W., Wang, X., Zhang, Y., Zhang, L., Liu, X., Yen, Y., Lai, L., Forman, B. M., Xu, Z., Xu, R. & Huang, W., 五月 1 2012, 於 : Molecular Endocrinology. 26, 5, p. 775-785 11 p.

研究成果: 雜誌貢獻文章

Hepatocellular Carcinoma
Liver Neoplasms
Cytoplasmic and Nuclear Receptors
Hepatocyte Nuclear Factor 1
Genes
24 引文 (Scopus)

Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia

Lin, H. H., Li, X., Chen, J. L., Sun, X., Cooper, F. N., Chen, Y. R., Zhang, W., Chung, Y., Li, A., Cheng, C. T., Yang, L., Deng, X. T., Liu, X., Yen, Y., Johnson, D. L., Shih, H. M., Yang, A. & Ann, D. K., 三月 1 2012, 於 : Molecular and Cellular Biology. 32, 6, p. 1124-1138 15 p.

研究成果: 雜誌貢獻文章

Epidermal Growth Factor Receptor
Adenosine Triphosphatases
Breast Neoplasms
Down-Regulation
Cellular Spheroids
5 引文 (Scopus)

Markers for efficacy of mammalian target of rapamycin inhibitor

Liao, Y. M., Sy, A. & Yen, Y., 十月 2012, 於 : Anticancer Research. 32, 10, p. 4235-4244 10 p.

研究成果: 雜誌貢獻文章

Sirolimus
Intercellular Signaling Peptides and Proteins
Carcinogenesis
Biomarkers
Proteins
37 引文 (Scopus)

Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer

Gaur, S., Chen, L., Yen, T., Wang, Y., Zhou, B., Davis, M. & Yen, Y., 七月 1 2012, 於 : Nanomedicine: Nanotechnology, Biology, and Medicine. 8, 5, p. 721-730 10 p.

研究成果: 雜誌貢獻文章

Camptothecin
Cyclodextrins
Stomach Neoplasms
Cells
Tumors

Ribonucleotide reductase and non-small cell lung cancer

Hsu, N. Y., Lee, H., Cheng, Y. W. & Yen, Y., 一月 1 2012, 於 : Chinese Journal of Lung Cancer. 15, 11, p. 619-623 5 p.

研究成果: 雜誌貢獻文章

Ribonucleotide Reductases
Non-Small Cell Lung Carcinoma
81 引文 (Scopus)

ROS1 as a 'druggable' receptor tyrosine kinase: Lessons learned from inhibiting the ALK pathway

Ou, S. H. I., Tan, J., Yen, Y. & Soo, R. A., 四月 2012, 於 : Expert Review of Anticancer Therapy. 12, 4, p. 447-456 10 p.

研究成果: 雜誌貢獻文章

Receptor Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Cholangiocarcinoma
Glioblastoma
Phosphotransferases
20 引文 (Scopus)

RRM2B suppresses activation of the oxidative stress pathway and is Up-regulated by P53 during senescence

Kuo, M. L., Sy, A. J., Xue, L., Chi, M., Michelle, M. T., Yen, T., Chiang, M. I., Chang, L., Chu, P. & Yen, Y., 十一月 22 2012, 於 : Scientific Reports. 2, 822.

研究成果: 雜誌貢獻文章

Oxidative Stress
Fibroblasts
Prostatic Intraepithelial Neoplasia
Deoxyribonucleosides
Ribonucleotide Reductases
23 引文 (Scopus)

Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers

Hu, H., Zhang, H., Ge, W., Liu, X., Loera, S., Chu, P., Chen, H., Peng, J., Zhou, L., Yu, S., Yuan, Y., Zhang, S., Lai, L., Yen, Y. & Zheng, S., 十月 1 2012, 於 : Clinical Cancer Research. 18, 19, p. 5438-5448 11 p.

研究成果: 雜誌貢獻文章

Cysteine
Colorectal Neoplasms
Survival
Proteins
Epithelial-Mesenchymal Transition
25 引文 (Scopus)

Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice

Synold, T. W., Xi, B., Wu, J., Yen, Y., Li, B. C., Yang, F., Phillips, J. W., Nickols, N. G. & Dervan, P. B., 十月 1 2012, 於 : Cancer Chemotherapy and Pharmacology. 70, 4, p. 617-625 9 p.

研究成果: 雜誌貢獻文章

Pyrroles
Pharmacokinetics
Nylons
Toxicity
Cell culture
57 引文 (Scopus)

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth

Rahman, M. A., Amin, A. R. M. R., Wang, X., Zuckerman, J. E., Choi, C. H. J., Zhou, B., Wang, D., Nannapaneni, S., Koenig, L., Chen, Z., Chen, Z. G., Yen, Y., Davis, M. E. & Shin, D. M., 五月 10 2012, 於 : Journal of Controlled Release. 159, 3, p. 384-392 9 p.

研究成果: 雜誌貢獻文章

Nanoparticles
Small Interfering RNA
Neck
Head
Growth
5 引文 (Scopus)

The utility of tumor-specifically internalizing peptides for targeted siRNA delivery into human solid tumors

Un, F., Zhou, B. & Yen, Y., 十一月 1 2012, 於 : Anticancer Research. 32, 11, p. 4685-4690 6 p.

研究成果: 雜誌貢獻文章

Small Interfering RNA
Peptides
Neoplasms
Breast Neoplasms
Ribonucleotides
17 引文 (Scopus)

Γ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers

Fu, S., Yang, Y., Tirtha, D., Yen, Y., Zhou, B. S., Zhou, M. M., Ohlmeyer, M., Ko, E. C., Cagan, R., Rosenstein, B. S., Chen, S. H. & Kao, J., 六月 29 2012, 於 : PLoS One. 7, 6, e38465.

研究成果: 雜誌貢獻文章

ribonucleotide reductase
Ribonucleotide Reductases
Assays
Screening
Ionizing radiation
2011
28 引文 (Scopus)

A bias-reducing strategy in profiling small RNAs using Solexa

Sun, G., Wu, X., Wang, J., Li, H., Li, X., Gao, H., Rossi, J. & Yen, Y., 十二月 1 2011, 於 : RNA. 17, 12, p. 2256-2262 7 p.

研究成果: 雜誌貢獻文章

RNA
Technology
High-Throughput Nucleotide Sequencing
Small Untranslated RNA
Research
18 引文 (Scopus)

A phase II study of the antisense oligonucleotide GTI-2040 plus docetaxel and prednisone as first-line treatment in castration-resistant prostate cancer

Sridhar, S. S., Canil, C. M., Chi, K. N., Hotte, S. J., Ernst, S., Wang, L., Chen, E. X., Juhasz, A., Yen, Y., Murray, P., Zwiebel, J. A. & Moore, M. J., 四月 1 2011, 於 : Cancer Chemotherapy and Pharmacology. 67, 4, p. 927-933 7 p.

研究成果: 雜誌貢獻文章

docetaxel
Antisense Oligonucleotides
Castration
Prednisone
Prostatic Neoplasms
4 引文 (Scopus)

Canonical nuclear factor κB pathway links tumorigenesis of synchronous mantle-cell lymphoma, clear-cell renal-cell carcinoma, and GI stromal tumor

Guo, R., Chang, L., Liu, Z., Li, A. X., Huang, Q., Ann, D. K., Wang, H. C., Lin, C. W., Wu, X., Yuan, Y. C. & Yen, Y., 四月 1 2011, 於 : Journal of Clinical Oncology. 29, 10

研究成果: 雜誌貢獻文章

Neoplastic Gene Expression Regulation
Murine-Derived Monoclonal Antibodies
Digestive System Surgical Procedures
Antineoplastic Combined Chemotherapy Protocols
Multiple Primary Neoplasms
69 引文 (Scopus)

Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels

Kretzner, L., Scuto, A., Dino, P. M., Kowolik, C. M., Wu, J., Ventura, P., Jove, R., Forman, S. J., Yen, Y. & Kirschbaum, M. H., 六月 1 2011, 於 : Cancer Research. 71, 11, p. 3912-3920 9 p.

研究成果: 雜誌貢獻文章

Aurora Kinases
Histone Deacetylase Inhibitors
MicroRNAs
Lymphoma
Acetylation
Thoracic Wall
Positron-Emission Tomography
Hepatocellular Carcinoma
Neoplasm Metastasis
Phosphoric Monoester Hydrolases
151 引文 (Scopus)

FZD7 has a critical role in cell proliferation in triple negative breast cancer

Yang, L., Wu, X., Wang, Y., Zhang, K., Wu, J., Yuan, Y. C., Deng, X., Chen, L., Kim, C. C. H., Lau, S., Somlo, G. & Yen, Y., 十月 27 2011, 於 : Oncogene. 30, 43, p. 4437-4446 10 p.

研究成果: 雜誌貢獻文章

Triple Negative Breast Neoplasms
Wnt Signaling Pathway
Cell Proliferation
T Cell Transcription Factor 1
Breast Neoplasms
35 引文 (Scopus)

High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis

Li, A. Y. J., Lin, H. H., Kuo, C. Y., Shih, H. M., Wang, C. C. C., Yen, Y. & Ann, D. K., 七月 1 2011, 於 : Molecular and Cellular Biology. 31, 13, p. 2605-2617 13 p.

研究成果: 雜誌貢獻文章

High Mobility Group Proteins
varespladib methyl
Reverse Transcription
Carcinogenesis
Telomerase
21 引文 (Scopus)

Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors

Gaur, S., Chen, L., Yang, L., Wu, X., Un, F. & Yen, Y., 十二月 1 2011, 於 : Cancer Letters. 311, 1, p. 20-28 9 p.

研究成果: 雜誌貢獻文章

Topoisomerase II Inhibitors
Drug Resistance
Doxorubicin
Cisplatin
DNA Damage
29 引文 (Scopus)

Mechanistic control of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) splice isoforms by the heterogeneous nuclear ribonuclear proteins hnRNP L, hnRNP A1, and hnRNP M

Dery, K. J., Gaur, S., Gencheva, M., Yen, Y., Shively, J. E. & Gaur, R. K., 五月 6 2011, 於 : Journal of Biological Chemistry. 286, 18, p. 16039-16051 13 p.

研究成果: 雜誌貢獻文章

Heterogeneous-Nuclear Ribonucleoprotein Group M
Heterogeneous-Nuclear Ribonucleoprotein L
Carcinoembryonic Antigen
Cell Adhesion Molecules
Nuclear Proteins
106 引文 (Scopus)

Overexpression of HMGA2 promotes metastasis and impacts survival of colorectal cancers

Wang, X., Liu, X., Li, A. Y. J., Chen, L., Lai, L., Lin, H. H., Hu, S., Yao, L., Peng, J., Loera, S., Xue, L., Zhou, B., Zhou, L., Zheng, S., Chu, P., Zhang, S., Ann, D. K. & Yen, Y., 四月 15 2011, 於 : Clinical Cancer Research. 17, 8, p. 2570-2580 11 p.

研究成果: 雜誌貢獻文章

varespladib methyl
Colorectal Neoplasms
Neoplasm Metastasis
Survival
Biomarkers
34 引文 (Scopus)

p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest

Zhang, K., Wu, J., Wu, X., Wang, X., Wang, Y., Zhou, N., Kuo, M. L., Liu, X., Zhou, B., Chang, L., Ann, D. & Yen, Y., 二月 1 2011, 於 : Molecular Cancer Therapeutics. 10, 2, p. 269-278 10 p.

研究成果: 雜誌貢獻文章

Cell Cycle Checkpoints
Cyclin D1
Neoplasms
DNA Damage
KB Cells
13 引文 (Scopus)

Phase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancer

Ocean, A. J., Christos, P., Sparano, J. A., Matulich, D., Kaubish, A., Siegel, A., Sung, M., Ward, M. M., Hamel, N., Espinoza-Delgado, I., Yen, Y. & Lane, M. E., 八月 1 2011, 於 : Cancer Chemotherapy and Pharmacology. 68, 2, p. 379-388 10 p.

研究成果: 雜誌貢獻文章

gemcitabine
Biliary Tract Neoplasms
Ribonucleotide Reductases
Liver
Biliary Tract
43 引文 (Scopus)

Ribonucleotide reductase small subunit M2B prognoses better survival in colorectal cancer

Liu, X., Lai, L., Wang, X., Xue, L., Leora, S., Wu, J., Hu, S., Zhang, K., Kuo, M. L., Zhou, L., Zhang, H., Wang, Y., Wang, Y., Zhou, B., Nelson, R. A., Zheng, S., Zhang, S., Chu, P. & Yen, Y., 五月 1 2011, 於 : Cancer Research. 71, 9, p. 3202-3213 12 p.

研究成果: 雜誌貢獻文章

Ribonucleotide Reductases
Colorectal Neoplasms
Survival
Neoplasms
Multivariate Analysis
10 引文 (Scopus)

Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and function in KB and PC-3 cancer cells

Wang, X., Liu, X., Xue, L., Zhang, K., Kuo, M. L., Hu, S., Zhou, B., Ann, D., Zhang, S. & Yen, Y., 六月 24 2011, 於 : Biochemical and Biophysical Research Communications. 410, 1, p. 102-107 6 p.

研究成果: 雜誌貢獻文章

Ribonucleotide Reductases
Mitochondria
Homeostasis
Cells
Mitochondrial DNA
160 引文 (Scopus)

Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma

Chen, T., Xie, G., Wang, X., Fan, J., Qiu, Y., Zheng, X., Qi, X., Cao, Y., Su, M., Wang, X., Xu, L. X., Yen, Y., Liu, P. & Jia, W., 七月 1 2011, 於 : Molecular and Cellular Proteomics. 10, 7

研究成果: 雜誌貢獻文章

Biomarkers
Metabolites
Liver
Hepatocellular Carcinoma
Urine
10 引文 (Scopus)

Small interfering RNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines

Tiemann, K., Alluin, J. V., Honegger, A., Chomchan, P., Gaur, S., Yun, Y., Forman, S. J., Rossi, J. J. & Chen, R. W., 十一月 1 2011, 於 : Leukemia and Lymphoma. 52, 11, p. 2148-2154 7 p.

研究成果: 雜誌貢獻文章

Cyclin D2
Mantle-Cell Lymphoma
Cyclin D1
Small Interfering RNA
Cell Line
16 引文 (Scopus)

Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3′-C-methyl- ribonucleosides as antitumor agents

Cappellacci, L., Petrelli, R., Franchetti, P., Vita, P., Kusumanchi, P., Kumar, M., Jayaram, H. N., Zhou, B., Yen, Y. & Grifantini, M., 五月 1 2011, 於 : European Journal of Medicinal Chemistry. 46, 5, p. 1499-1504 6 p.

研究成果: 雜誌貢獻文章

Ribonucleosides
Ribonucleotide Reductases
Ribose
Adenine
Bioactivity
81 引文 (Scopus)

The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival

Scuto, A., Krejci, P., Popplewell, L., Wu, J., Wang, Y., Kujawski, M., Kowolik, C., Xin, H., Chen, L., Wang, Y., Kretzner, L., Yu, H., Wilcox, W. R., Yen, Y., Forman, S. & Jove, R., 一月 1 2011, 於 : Leukemia. 25, 3, p. 538-550 13 p.

研究成果: 雜誌貢獻文章

Cell Survival
Growth
Cyclin D2
Multiple Myeloma
Mesenchymal Stromal Cells
2010
13 引文 (Scopus)

A newly identified variation at the entry of the recurrent laryngeal nerve into the larynx

Shao, T., Yang, W., Zhang, T., Wang, Y., Jin, X., Li, Q., Kuang, J., Qiu, W., Chu, P. G. & Yen, Y., 十二月 1 2010, 於 : Journal of Investigative Surgery. 23, 6, p. 314-320 7 p.

研究成果: 雜誌貢獻文章

Recurrent Laryngeal Nerve
Larynx
Thyroidectomy
Thyroid Gland
Joints
35 引文 (Scopus)

Antitumor activity of targeting Src kinases in endothelial and myeloid cell compartments of the tumor microenvironment

Liang, W., Kujawski, M., Wu, J., Lu, J., Herrmann, A., Loera, S., Yen, Y., Lee, F., Yu, H., Wen, W. & Jove, R., 二月 1 2010, 於 : Clinical Cancer Research. 16, 3, p. 924-935 12 p.

研究成果: 雜誌貢獻文章

Tumor Microenvironment
src-Family Kinases
Myeloid Cells
Endothelial Cells
Neoplasms
153 引文 (Scopus)

A subpopulation of CD133+ cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy

Zhang, Q., Shi, S., Yen, Y., Brown, J., Ta, J. Q. & Le, A. D., 三月 28 2010, 於 : Cancer Letters. 289, 2, p. 151-160 10 p.

研究成果: 雜誌貢獻文章

Neoplastic Stem Cells
Squamous Cell Carcinoma
Drug Therapy
Paclitaxel
Cell Line
60 引文 (Scopus)

Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1α/VEGF signaling pathways in human breast cancer cells

Tang, X., Zhang, Q., Shi, S., Yen, Y., Li, X., Zhang, Y., Zhou, K. & Le, A. D., 一月 1 2010, 於 : International Journal of Cancer. 126, 1, p. 90-103 14 p.

研究成果: 雜誌貢獻文章

pamidronate
Hypoxia-Inducible Factor 1
Clodronic Acid
Diphosphonates
Somatomedins
2 引文 (Scopus)

Bortezomib therapeutic effect is associated with expression and mutation of FGFR3 in human lymphoma cells

Zheng, W., Guan, M., Zhu, L., Cai, Z., Chung, V., Huang, H. & Yen, Y., 六月 1 2010, 於 : Anticancer Research. 30, 6, p. 1921-1930 10 p.

研究成果: 雜誌貢獻文章

Receptor, Fibroblast Growth Factor, Type 3
Therapeutic Uses
Lymphoma
U937 Cells
Mutation