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研究成果 1999 2019

  • 2311 引文
  • 26 h-指數
  • 109 文章
  • 1 回顧型文獻
1999
15 引文 (Scopus)

Engineered recombinant factor VII Q217 variants with altered inhibitor specificities

Chang, Y. J., Hamaguchi, N., Chang, S. C., Ruf, W., Shen, M. C. & Lin, S. W., 八月 24 1999, 於 : Biochemistry. 38, 34, p. 10940-10948 9 p.

研究成果: 雜誌貢獻文章

Factor VII
Antithrombin III
Glycine
benzoyl-Ile-Glu-Gly-Arg-p-nitroanilide
Chymotrypsinogen
2001
9 引文 (Scopus)

The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitors

Hsu, Y. C., Hamaguchi, N., Chang, Y. J. & Lin, S. W., 九月 18 2001, 於 : Biochemistry. 40, 37, p. 11261-11269 9 p.

研究成果: 雜誌貢獻文章

Factor IX
Factor VIIIa
Factor IXa
Antithrombin III
Substrates
2002
31 引文 (Scopus)
Factor VIIIa
Mutagenesis
Factor IX
Epidermal Growth Factor
Alanine
2003
7 引文 (Scopus)

Discontinuous residues of factor IX constitute a surface for binding the anti-factor IX monoclonal antibody A-5

Chang, Y. J., Wu, H. L., Hsu, Y. C., Hamaguchi, N., Shi, G. Y., Shen, M. C. & Lin, S. W., 2003, 於 : Thrombosis Research. 111, 4-5, p. 293-299 7 p.

研究成果: 雜誌貢獻文章

Factor IX
Monoclonal Antibodies
Alanine
Factor VIIIa
Factor VIII
2004
10 引文 (Scopus)
Factor IXa
Factor X
Platelets
Application programs
Epidermal Growth Factor
2005
57 引文 (Scopus)

Evidence of human thrombomodulin domain as a novel angiogenic factor

Shi, C. S., Shi, G. Y., Chang, Y. S., Han, H. S., Kuo, C. H., Liu, C., Huang, H. C., Chang, Y. J., Chen, P. S. & Wu, H. L., 四月 5 2005, 於 : Circulation. 111, 13, p. 1627-1636 10 p.

研究成果: 雜誌貢獻文章

Thrombomodulin
Angiogenesis Inducing Agents
Endothelial Cells
Human Umbilical Vein Endothelial Cells
Epidermal Growth Factor
2006
94 引文 (Scopus)

Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells

Zhang, C., Yeh, S., Chen, Y. T., Wu, C. C., Chuang, K. H., Lin, H. Y., Wang, R. S., Chang, Y. J., Mendis-Handagama, C., Hu, L., Lardy, H. & Chang, C., 十一月 21 2006, 於 : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17718-17723 6 p.

研究成果: 雜誌貢獻文章

Oligospermia
Fertility
Testis
Androgen Receptors
Germ Cells
2007
118 引文 (Scopus)

ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

Yang, Z., Chang, Y. J., Yu, I. C., Yeh, S., Wu, C. C., Miyamoto, H., Merry, D. E., Sobue, G., Chen, L. M., Chang, S. S. & Chang, C., 三月 2007, 於 : Nature Medicine. 13, 3, p. 348-353 6 p.

研究成果: 雜誌貢獻文章

Atrophic Muscular Disorders
Androgen Receptors
Phenotype
Degradation
Agglomeration
249 引文 (Scopus)

Promotion of bladder cancer development and progression by androgen receptor signals

Miyamoto, H., Yang, Z., Chen, Y. T., Ishiguro, H., Uemura, H., Kubota, Y., Nagashima, Y., Chang, Y. J., Hu, Y. C., Tsai, M. Y., Yeh, S., Messing, E. M. & Chang, C., 四月 4 2007, 於 : Journal of the National Cancer Institute. 99, 7, p. 558-568 11 p.

研究成果: 雜誌貢獻文章

Androgen Receptors
Urinary Bladder Neoplasms
Androgens
Androgen Antagonists
Dihydrotestosterone
13 引文 (Scopus)

Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54

Yang, Z., Chang, Y. J., Miyamoto, H., Yeh, S., Yao, J. L., Di Sant'Agnese, P. A., Tsai, M. Y. & Chang, C., 三月 2007, 於 : Endocrinology. 148, 3, p. 1340-1349 10 p.

研究成果: 雜誌貢獻文章

Heterogeneous-Nuclear Ribonucleoproteins
Androgen Receptors
Transcriptional Activation
Prostatic Neoplasms
Growth
70 引文 (Scopus)

Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth

Yang, Z., Chang, Y. J., Miyamoto, H., Ni, J., Niu, Y., Chen, Z., Chen, Y. L., Yao, J. L., Di Sant'Agnese, P. A. & Chang, C., 二月 2007, 於 : Molecular Endocrinology. 21, 2, p. 343-358 16 p.

研究成果: 雜誌貢獻文章

Androgen Receptors
Transcriptional Activation
Prostatic Neoplasms
Growth
transgelin
2008
6 引文 (Scopus)

Mutation of human plasminogen kringle 1-5 enhances anti-angiogenic action via increased interaction with integrin αvβ3

Chang, P. C., Chang, Y. J., Wu, H. L., Chang, C. W., Lin, C. I., Wang, W. C. & Shi, G. Y., 四月 2008, 於 : Thrombosis and Haemostasis. 99, 4, p. 729-738 10 p.

研究成果: 雜誌貢獻文章

Kringles
Integrins
Mutation
Endothelial Cells
Angiostatins
28 引文 (Scopus)

Subfertility with defective folliculogenesis in female mice lacking testicular orphan nuclear receptor 4

Chen, L. M., Wang, R. S., Lee, Y. F., Liu, N. C., Chang, Y. J., Wu, C. C., Xie, S., Hung, Y. C. & Chang, C., 四月 2008, 於 : Molecular Endocrinology. 22, 4, p. 858-867 10 p.

研究成果: 雜誌貢獻文章

Orphan Nuclear Receptors
Infertility
LH Receptors
Corpus Luteum
Nuclear Receptor Subfamily 2, Group C, Member 2
2009
59 引文 (Scopus)
Nicotinic Receptors
Carcinogens
Colonic Neoplasms
Tobacco
Cell Movement
2010
37 引文 (Scopus)

Glucose-Regulated protein 78 (GRP78) silencing enhances cell migration but does not influence cell proliferation in hepatocellular carcinoma

Chang, Y-J., Chiu, C. C., Wu, C-H., An, J., Wu, C. C., Liu, T. Z., Wei, P-L. & Huang, M-T., 六月 2010, 於 : Annals of Surgical Oncology. 17, 6, p. 1703-1709 7 p.

研究成果: 雜誌貢獻文章

Cell Movement
Hepatocellular Carcinoma
Cell Proliferation
Small Interfering RNA
glucose-regulated proteins
61 引文 (Scopus)

Glucose-regulated protein 78 Is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma

Chiou, J-F., Tai, C-J., Huang, M-T., Wei, P-L., Wang, Y. H., An, J., Wu, C-H., Liu, T. Z. & Chang, Y-J., 二月 2010, 於 : Annals of Surgical Oncology. 17, 2, p. 603-612 10 p.

研究成果: 雜誌貢獻文章

Hepatocellular Carcinoma
Hep G2 Cells
sorafenib
glucose-regulated proteins
Neoplasms
24 引文 (Scopus)
Thrombomodulin
Cadherins
Cell Movement
Hepatocellular Carcinoma
Gene Expression
98 引文 (Scopus)

Overexpression and activation of the α9-nicotinic receptor during tumorigenesis in human breast epithelial cells

Lee, C. H., Huang, C. S., Chen, C. S., Tu, S. H., Wang, Y. J., Chang, Y. J., Tam, K. W., Wei, P. L., Cheng, T. C., Chu, J. S., Chen, L. C., Wu, C. H. & Ho, Y. S., 九月 8 2010, 於 : Journal of the National Cancer Institute. 102, 17, p. 1322-1335 14 p.

研究成果: 雜誌貢獻文章

Nicotinic Receptors
Nicotine
Carcinogenesis
Breast
Epithelial Cells
20 引文 (Scopus)

Role of DNA methyltransferase 1 in hormone-resistant prostate cancer

Chen, M. F., Chen, W. C., Chang, Y. J., Wu, C. F. & Wu, C. T., 九月 2010, 於 : Journal of Molecular Medicine. 88, 9, p. 953-962 10 p.

研究成果: 雜誌貢獻文章

Methyltransferases
Prostatic Neoplasms
Hormones
DNA
Androgen Receptors
2011
5 引文 (Scopus)
Colorectal Neoplasms
Epidemiology
Smoking
Microsatellite Instability
Neoplasms
44 引文 (Scopus)

Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells

Lee, C. H., Chang, Y. C., Chen, C. S., Tu, S. H., Wang, Y. J., Chen, L. C., Chang, Y. J., Wei, P. L., Chang, H. W., Chang, C. H., Huang, C. S., Wu, C. H. & Ho, Y. S., 九月 2011, 於 : Breast Cancer Research and Treatment. 129, 2, p. 331-345 15 p.

研究成果: 雜誌貢獻文章

Nicotinic Receptors
Nicotine
Estrogen Receptors
Estrogens
Breast Neoplasms
38 引文 (Scopus)

Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation

Chen, C. H., Chang, Y. J., Ku, M. S. B., Chung, K. T. & Yang, J. T., 三月 2011, 於 : Journal of Molecular Medicine. 89, 3, p. 303-315 13 p.

研究成果: 雜誌貢獻文章

temozolomide
Valproic Acid
Glioma
Oxidation-Reduction
Apoptosis
29 引文 (Scopus)
Curcumin
Hepatocellular Carcinoma
In Situ Nick-End Labeling
Small Interfering RNA
Cell Cycle
29 引文 (Scopus)
Class E Scavenger Receptors
Chaperonin 60
Chlamydophila pneumoniae
Atherosclerosis
Endothelial Cells
48 引文 (Scopus)

Nicotine enhances colon cancer cell migration by induction of fibronectin

Wei, P. L., Kuo, L. J., Huang, M. T., Ting, W. C., Ho, Y. S., Wang, W., An, J. & Chang, Y. J., 六月 2011, 於 : Annals of Surgical Oncology. 18, 6, p. 1782-1790 9 p.

研究成果: 雜誌貢獻文章

Nicotine
Fibronectins
Colonic Neoplasms
Cell Movement
Epithelial-Mesenchymal Transition
77 引文 (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C-H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S-H., Wang, Y. J., Chen, L-C., Chang, Y-J., Wei, P-L., Yang, Y-Y., Wu, C-H. & Ho, Y-S., 一月 2011, 於 : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

研究成果: 雜誌貢獻文章

Cyclin D3
Nicotinic Receptors
Nicotine
Down-Regulation
Cell Proliferation
43 引文 (Scopus)

Nicotine promotes cell migration through alpha7 nicotinic acetylcholine receptor in gastric cancer cells

Lien, Y. C., Wang, W., Kuo, L. J., Liu, J. J., Wei, P. L., Ho, Y. S., Ting, W. C., Wu, C. H. & Chang, Y. J., 九月 2011, 於 : Annals of Surgical Oncology. 18, 9, p. 2671-2679 9 p.

研究成果: 雜誌貢獻文章

alpha7 Nicotinic Acetylcholine Receptor
Nicotine
Stomach Neoplasms
Cell Movement
Cadherins
14 引文 (Scopus)

Normoxically overexpressed hypoxia inducible factor 1-alpha is involved in arsenic trioxide resistance acquisition in hepatocellular carcinoma

Tung, J. N., Cheng, Y. W., Hsu, C. H., Liu, T. Z., Hsieh, P. Y., Ting, L. L., Ko, H. L., Chang, Y. J., Chiou, J. F. & Wu, A. T. H., 五月 2011, 於 : Annals of Surgical Oncology. 18, 5, p. 1492-1500 9 p.

研究成果: 雜誌貢獻文章

Hypoxia-Inducible Factor 1
Hepatocellular Carcinoma
Apoptosis
Carcinoma
arsenic trioxide
29 引文 (Scopus)
Rectal Neoplasms
Disease-Free Survival
Antidiarrheals
Defecation
Radiotherapy
59 引文 (Scopus)

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

Tu, S. H., Ku, C. Y., Ho, C. T., Chen, C. S., Huang, C. S., Lee, C. H., Chen, L. C., Pan, M. H., Chang, H. W., Chang, C. H., Chang, Y. J., Wei, P. L., Wu, C. H. & Ho, Y. S., 三月 2011, 於 : Molecular Nutrition and Food Research. 55, 3, p. 455-466 12 p.

研究成果: 雜誌貢獻文章

cholinergic receptors
nicotine
epigallocatechin
Nicotinic Receptors
Polyphenols
9 引文 (Scopus)
Nicotinic Receptors
Nicotine
Breast Neoplasms
Neoplasm Metastasis
Cell Movement
2012
15 引文 (Scopus)
docetaxel
Solanum nigrum
Autophagy
Endometrial Neoplasms
Neoplasms
24 引文 (Scopus)
Rectal Neoplasms
Biopsy
Magnetic Resonance Spectroscopy
Survival Rate
Therapeutics
9 引文 (Scopus)

GroEL1, from chlamydia pneumoniae, induces vascular adhesion molecule 1 expression by p37AUF1 in endothelial cells and hypercholesterolemic rabbit

Huang, C. Y., Shih, C. M., Tsao, N. W., Chen, Y. H., Li, C. Y., Chang, Y. J., Chang, N. C., Ou, K. L., Lin, C. Y., Lin, Y. W., Nien, C. H. & Lin, F. Y., 八月 10 2012, 於 : PLoS One. 7, 8, e42808.

研究成果: 雜誌貢獻文章

Chlamydophila pneumoniae
Endothelial cells
blood vessels
endothelial cells
Blood Vessels
46 引文 (Scopus)

GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and akt pathway after epirubicin treatment in colon cancer DLD-1 cells

Chang, Y. J., Huang, Y. P., Li, Z. L. & Chen, C. H., 四月 18 2012, 於 : PLoS One. 7, 4, e35123.

研究成果: 雜誌貢獻文章

epirubicin
Epirubicin
Oxidative stress
colorectal neoplasms
Colonic Neoplasms
10 引文 (Scopus)
Curcumin
Hepatocellular Carcinoma
Small Interfering RNA
In Situ Nick-End Labeling
Cell Cycle
33 引文 (Scopus)
rho-Associated Kinases
HDL Lipoproteins
Healthy Volunteers
Phosphatidylinositol 3-Kinase
Cell Aging
22 引文 (Scopus)
Nicotinic Receptors
Fibronectins
Stomach Neoplasms
Cell Movement
alpha7 Nicotinic Acetylcholine Receptor
25 引文 (Scopus)
Vimentin
Cell Movement
Hepatocellular Carcinoma
Up-Regulation
Biosensing Techniques
22 引文 (Scopus)
Epithelial-Mesenchymal Transition
Cell Movement
Hepatocellular Carcinoma
Neoplasms
Vimentin
9 引文 (Scopus)

Survivin-mediated therapeutic efficacy of gemcitabine through glucose-regulated protein 78 in hepatocellular carcinoma

Hung, C. S., Lin, S. F., Liu, H. H., Kuo, L. J., Li, L. T., Su, H. Y., Liew, P. L., Lin, F. Y., Wei, P. L., Liu, D. Z. & Chang, Y. J., 八月 2012, 於 : Annals of Surgical Oncology. 19, 8, p. 2744-2752 9 p.

研究成果: 雜誌貢獻文章

gemcitabine
Hepatocellular Carcinoma
Therapeutics
DNA Nucleotidylexotransferase
glucose-regulated proteins
Atherosclerosis
Endothelial Cells
Scavenger Receptors
Coronary Vessels
Oxidized LDL Receptors
2013
37 引文 (Scopus)
docetaxel
Solanum nigrum
Autophagy
Fluorouracil
Doxorubicin
18 引文 (Scopus)

Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation

Yu, C. C., Wu, P. J., Hsu, J. L., Ho, Y. F., Hsu, L. C., Chang, Y. J., Chang, H. S., Chen, I. S. & Guh, J. H., 一月 2013, 於 : Prostate. 73, 2, p. 133-145 13 p.

研究成果: 雜誌貢獻文章

Caspases
70-kDa Ribosomal Protein S6 Kinases
Prostatic Neoplasms
Mitochondria
Down-Regulation
13 引文 (Scopus)
Fluorouracil
Cisplatin
Hepatocellular Carcinoma
Cell Death
Neoplasms
19 引文 (Scopus)
Vascular Endothelial Growth Factor Receptor-2
Colonic Neoplasms
Vascular Endothelial Growth Factor A
Down-Regulation
Growth
16 引文 (Scopus)
Learning Curve
Rectal Neoplasms
Laparoscopy
Surgical Blood Loss
Dissection
29 引文 (Scopus)
Curcumin
Therapeutic Uses
MicroRNAs
Hepatocellular Carcinoma
In Situ Nick-End Labeling
36 引文 (Scopus)
Epithelial-Mesenchymal Transition
MicroRNAs
Cell Movement
Hepatocellular Carcinoma
Cadherins
54 引文 (Scopus)

New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells

Lai, K. P., Huang, C. K., Chang, Y. J., Chung, C. Y., Yamashita, S., Li, L., Lee, S. O., Yeh, S. & Chang, C., 二月 2013, 於 : American Journal of Pathology. 182, 2, p. 460-473 14 p.

研究成果: 雜誌貢獻文章

Castration
Androgen Receptors
Prostate
Prostatic Neoplasms
Androgens