• 630 引文
  • 12 h-指數
1989 …2020

每年研究成果

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研究成果

  • 630 引文
  • 12 h-指數
  • 56 文章
  • 1 回顧型文獻
篩選
文章
2020

Integrin αvβ3 in the mediating effects of dihydrotestosterone and resveratrol on breast cancer cell proliferation

Ho, Y., Zi-Lin, L., Ya-Jung, S., Yi-Ru, C., Wang, K., Whang-Peng, J., Hung-Yun, L. & Davis, P. J., 四月 21 2020, 於 : International Journal of Molecular Sciences. 21, 8, 2906.

研究成果: 雜誌貢獻文章

開啟存取
1 引文 斯高帕斯(Scopus)

NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells

Ho, Y., Wu, C. Y., Chin, Y. T., Li, Z. L., Pan, Y. S., Huang, T. Y., Su, P. Y., Lee, S. Y., Crawford, D. R., Su, K. W., Chiu, H. C., Shih, Y. J., Changou, C. A., Yang, Y. C. S. H., Whang-Peng, J., Chen, Y. R., Lin, H. Y., Mousa, S. A., Davis, P. J. & Wang, K., 二月 1 2020, 於 : Food and Chemical Toxicology. 136, p. 111092 111092.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2019

Discovery of Novel Irreversible HER2 Inhibitors for Breast Cancer Treatment

Tang, J. Y., Ho, Y., Chang, C. Y. & Liu, H. L., 四月 2019, 於 : Journal of Biomedical Science and Engineering.

研究成果: 雜誌貢獻文章

Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells

Ho, Y., Wang, S. H., Chen, Y. R., Li, Z. L., Chin, Y. T., Yang, Y. C. S. H., Wu, Y. H., Su, K. W., Chu, H. R., Chiu, H. C., Crawford, D. R., Shih, Y. J., Grasso, P., Tang, H. Y., Lin, H. Y., Davis, P. J., Whang-Peng, J. & Wang, K., 十一月 1 2019, 於 : Food and Chemical Toxicology. 133, p. 110808 110808.

研究成果: 雜誌貢獻文章

Tetrac and NDAT Induce Anti-proliferation via Integrin αvβ3 in Colorectal Cancers With Different K-RAS Status

Chin, Y-T., He, Z-R., Chen, C-L., Chu, H-C., Ho, Y., Su, P-Y., Yang, Y-C. S. H., Wang, K., Shih, Y-J., Chen, Y-R., Pedersen, J. Z., Incerpi, S., Nana, A. W., Tang, H-Y., Lin, H-Y., Mousa, S. A., Davis, P. J. & Whang-Peng, J., 一月 1 2019, 於 : Frontiers in Endocrinology. 10, APR, p. 130 130.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2018

Heteronemin induces anti-Proliferation in cholangiocarcinoma cells via inhibiting TGF-β pathway

Lin, H. Y., Tey, S. L., Ho, Y., Chin, Y. T., Wang, K., Whang-Peng, J., Shih, Y. J., Chen, Y. R., Yang, Y. N., Chen, Y. C., Liu, Y. C., Tang, H. Y. & Yang, Y. C. SH., 十二月 6 2018, 於 : Marine Drugs. 16, 12, 489.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Inhibitory effect of Anoectochilus formosanus extract on hyperglycemia-related PD-L1 expression and cancer proliferation

Ho, Y., Chen, Y. F., Wang, L. H., Hsu, K. Y., Chin, Y. T., Yang, Y. C. S. H., Wang, S. H., Chen, Y. R., Shih, Y. J., Liu, L. F., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H. Y., Liu, H. L. & Lin, S. J., 八月 2 2018, 於 : Frontiers in Pharmacology. 9, AUG, p. 807 807.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

Nana, A. W., Wu, S. Y., Yang, Y. C. S., Chin, Y. T., Cheng, T. M., Ho, Y., Li, W. S., Liao, Y. M., Chen, Y. R., Shih, Y. J., Liu, Y. R., Pedersen, J., Incerpi, S., Hercbergs, A., Liu, L. F., Whang-Peng, J., Davis, P. J. & Lin, H. Y., 十月 1 2018, 於 : Hormones and Cancer. 9, 5, p. 349-360 12 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells

Lin, S. J., Chin, Y. T., Ho, Y., Chou, S. Y., Sh Yang, Y. C., Nana, A. W., Su, K. W., Lim, Y. T., Wang, K., Lee, SY. Y., Shih, Y. J., Chen, Y. R., Whang-Peng, J., Davis, P. J., Lin, H. Y. & Fu, E., 十月 1 2018, 於 : Food and Chemical Toxicology. 120, p. 1-11 11 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Resveratrol induces sumoylated COX-2-dependent anti-proliferation in human prostate cancer LNCaP cells

Cheng, T. M., Chin, Y. T., Ho, Y., Chen, Y. R., Yang, Y. N., Yang, Y. C., Shih, Y. J., Lin, T. I., Lin, H. Y. & Davis, P. J., 二月 1 2018, 於 : Food and Chemical Toxicology. 112, p. 67-75 9 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R

Ho, Y., SH Yang, Y. C., Chin, Y. T., Chou, S. Y., Chen, Y. R., Shih, Y. J., Whang-Peng, J., Changou, C. A., Liu, H. L., Lin, S. J., Tang, H. Y., Lin, H. Y. & Davis, P. J., 十月 1 2018, 於 : Food and Chemical Toxicology. 120, p. 346-355 10 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer

Nana, A. W., Chin, Y. T., Lin, C. Y., Ho, Y., Bennett, J. A., Shih, Y. J., Chen, Y. R., Changou, C. A., Pedersen, J. Z., Incerpi, S., Liu, L. F., Whang-Peng, J., Fu, E., Li, W. S., Mousa, S. A., Lin, H. Y. & Davis, P. J., 三月 1 2018, 於 : Endocrine-Related Cancer. 25, 3, p. 279-293 15 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

Thyroxine inhibits resveratrol-caused apoptosis by PD-L1 in ovarian cancer cells

Chin, Y. T., Wei, P. L., Ho, Y., Nana, A. W., Changou, C. A., Chen, Y. R., Yang, Y. C. SH., Hsieh, M. T., Hercbergs, A., Davis, P. J., Shih, Y. J. & Lin, H. Y., 五月 1 2018, 於 : Endocrine-Related Cancer. 25, 5, p. 533-545 13 p.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)
2017

Allopurinol, benzbromarone and risk of coronary heart disease in gout patients: A population-based study

Lin, H. C., Daimon, M., Wang, C. H., Ho, Y., Uang, Y. S., Chiang, S. J. & Wang, L. H., 四月 15 2017, 於 : International Journal of Cardiology. 233, p. 85-90 6 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
2015

Computer-aided discovery of novel non-peptide inhibitors against amyloid-beta (Aβ) peptide aggregation for treating Alzheimer's disease

Zhou, Z. L., Ho, Y., Liu, H. L., Elumalai, P. & Chen, W. H., 五月 24 2015, 於 : Molecular Simulation. 41, 8, p. 622-632 11 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Discovery of novel 5α-reductase type II inhibitors by pharmacophore modelling, virtual screening, molecular docking and molecular dynamics simulations

Wang, J. L., Liu, H. L., Zhou, Z. L., Chen, W. H. & Ho, Y., 三月 4 2015, 於 : Molecular Simulation. 41, 4, p. 287-297 11 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
2014

A combination of pharmacophore and in silico approaches for identification of potential transthyretin amyloidosis inhibitors

Zhou, Z. L., Liu, H. L., Wu, J. W., Tsao, C. W., Chen, W. H., Liu, K. T. & Ho, Y., 一月 2014, 於 : Letters in Drug Design and Discovery. 11, 3, p. 339-348 10 p.

研究成果: 雜誌貢獻文章

Computer-aided discovery of potential inhibitors for transthyretin-related amyloidosis

Zhou, Z. L., Liu, H. L., Wu, J. W., Tsao, C. W., Chen, W. H., Liu, K. T. & Ho, Y., 2014, 於 : Journal of the Chinese Chemical Society. 61, 2, p. 263-273 11 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Structure-based pharmacophore modeling and virtual screening to identify novel inhibitors for anthrax lethal factor

Liao, H. S., Liu, H. L., Chen, W. H. & Ho, Y., 2014, 於 : Medicinal Chemistry Research. 23, 8, p. 3725-3732 8 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)
2013

Combining structure-based pharmacophore and in silico approaches to discover novel selective serotonin reuptake inhibitors

Zhou, Z. L., Liu, H. L., Wu, J. W., Tsao, C. W., Chen, W. H., Liu, K. T. & Ho, Y., 十二月 2013, 於 : Chemical Biology and Drug Design. 82, 6, p. 705-717 13 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
3 引文 斯高帕斯(Scopus)
2012

Ligand and structure-based pharmacophore modeling for the discovery of potential human HNMT inhibitors

Elumalai, P., Liu, H. L., Zhou, Z. L., Zhao, J. H., Chen, W., Chuang, C. K., Tsai, W. B. & Ho, Y., 一月 2012, 於 : Letters in Drug Design and Discovery. 9, 1, p. 17-29 13 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Pharmacophore modeling, virtual screening and docking studies to identify novel HNMT inhibitors

Elumalai, P., Liu, H. L., Zhao, J. H., Chen, W., Lin, D. S., Chuang, C. K., Tsai, W. B. & Ho, Y., 七月 2012, 於 : Journal of the Taiwan Institute of Chemical Engineers. 43, 4, p. 493-503 11 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

Pharmacophore modeling and virtual screening to design the potential influenza virus endonuclease inhibitors

Liao, H. S., Wu, J. W., Liu, H. L., Zhao, J. H., Tsao, C. W., Liu, K. T., Chuang, C. K., Lin, H. Y., Tsai, W. B. & Ho, Y., 十一月 2012, 於 : Journal of the Chinese Chemical Society. 59, 11, p. 1430-1438 9 p.

研究成果: 雜誌貢獻文章

2011

Insights into the structural stability and possible aggregation pathways of the LYQLEN peptides derived from human insulin

Lin, Y. F., Zhao, J. H., Liu, H. L., Wu, J. W., Chuang, C. K., Liu, K. T., Lin, H. Y., Tsai, W. B. & Ho, Y., 五月 2011, 於 : Journal of the Taiwan Institute of Chemical Engineers. 42, 3, p. 394-401 8 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies

Lu, S. H., Wu, J. W., Liu, H. L., Zhao, J. H., Liu, K. T., Chuang, C. K., Lin, H. Y., Tsai, W. B. & Ho, Y., 2011, 於 : Journal of Biomedical Science. 18, 1, 8.

研究成果: 雜誌貢獻文章

95 引文 斯高帕斯(Scopus)

The possible structural models for polyglutamine aggregation: A molecular dynamics simulations study

Zhou, Z. L., Zhao, J. H., Liu, H. L., Wu, J. W., Liu, K. T., Chuang, C. K., Tsai, W. B. & Ho, Y., 四月 2011, 於 : Journal of Biomolecular Structure and Dynamics. 28, 5, p. 743-758 16 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)
2010

Molecular dynamics simulations to investigate the stability and aggregation behaviour of the amyloid-forming peptide VQIVYK from tau protein

Zhao, J. H., Liu, H. L., Chuang, C. K., Liu, K. T., Tsai, W. B. & Ho, Y., 十一月 2010, 於 : Molecular Simulation. 36, 13, p. 1013-1024 12 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Structural stability and aggregation behavior of the VEALYL peptide derived from human insulin: a molecular dynamics simulation study.

Lin, Y. F., Zhao, J. H., Liu, H. L., Liu, K. T., Chen, J. T., Tsai, W. B. & Ho, Y., 2010, 於 : Biopolymers. 94, 3, p. 269-278 10 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

The importance of steric zipper on the aggregation of the MVGGVV peptide derived from the amyloid β peptide

Chang, L. K., Zhao, J. H., Liu, H. L., Wu, J. W., Chuang, C. K., Liu, K. T., Chen, J. T., Tsai, W. B. & Ho, Y., 八月 2010, 於 : Journal of Biomolecular Structure and Dynamics. 28, 1, p. 39-50 12 p.

研究成果: 雜誌貢獻文章

28 引文 斯高帕斯(Scopus)
2009

Effects of serotonin on acid secretion in isolated rat stomach: The role of 5-HT3 receptors

Lai, Y. C., Ho, Y., Huang, K. H. & Tsai, L-H., 2009, 於 : Chinese Journal of Physiology. 52, SUPPL. 5, p. 395-405 11 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Microbial transformation of isosteviol oxime and the inhibitory effects on NF-κB and AP-1 activation in LPS-stimulated macrophages

Chang, S. F., Chou, B. H., Yang, L. M., Hsu, F. L., Lin, W. K., Ho, Y. & Lin, S. J., 九月 1 2009, 於 : Bioorganic and Medicinal Chemistry. 17, 17, p. 6348-6353 6 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)

Molecular dynamics simulations to investigate the aggregation behaviors of the Aβ(17-42) oligomers

Zhao, J. H., Liu, H. L., Liu, Y. F., Lin, H. Y., Fang, H. W., Ho, Y. & Tsai, W. B., 二月 2009, 於 : Journal of Biomolecular Structure and Dynamics. 26, 4, p. 481-490 10 p.

研究成果: 雜誌貢獻文章

45 引文 斯高帕斯(Scopus)

Molecular dynamics simulations to investigate the relationship between the structural stability and amyloidogenesis of the wild-type and N-terminal hexapeptide deletion N6 2-microglobulin

Fang, P. S., Zhao, J. H., Liu, H. L., Liu, K. T., Chen, J. T., Tsai, W. B., Lin, H. Y., Fang, H. W. & Ho, Y., 八月 2009, 於 : Molecular Simulation. 35, 9, p. 755-765 11 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Molecular dynamics simulations to investigate the structural stability and aggregation behavior of the GGVVIA oligomers derived from amyloid β peptide

Chang, L. K., Zhao, J. H., Liu, H. L., Liu, K. T., Chen, J. T., Tsai, W. B. & Ho, Y., 六月 2009, 於 : Journal of Biomolecular Structure and Dynamics. 26, 6, p. 731-740 10 p.

研究成果: 雜誌貢獻文章

36 引文 斯高帕斯(Scopus)
2008

RING domains functioning as E3 ligases reveal distinct structural features: A molecular dynamics simulation study

Zhao, J. H., Yang, C. T., Wu, J. W., Tsai, W. B., Lin, H. Y., Fang, H. W., Ho, Y. & Liu, H. L., 八月 2008, 於 : Journal of Biomolecular Structure and Dynamics. 26, 1, p. 65-73 9 p.

研究成果: 雜誌貢獻文章

20 引文 斯高帕斯(Scopus)
2007

Insights into the conformational changes of several human lysozyme variants associated with hereditary systemic amyloidosis

Liu, H. L., Wu, Y. C., Zhao, J. H., Liu, Y. F., Huang, C. H., Fang, H. W. & Ho, Y., 一月 2007, 於 : Biotechnology Progress. 23, 1, p. 246-254 9 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Molecular dynamics simulations of human cystatin C and its L68Q varient to investigate the domain swapping mechanism

Liu, H. L., Lin, Y. M., Zhao, J. H., Hsieh, M. C., Lin, H. Y., Huang, C. H., Fang, H. W., Ho, Y. & Chen, W. Y., 十月 2007, 於 : Journal of Biomolecular Structure and Dynamics. 25, 2, p. 135-144 10 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

Molecular dynamics simulations to investigate the domain swapping mechanism of human cystatin C

Lin, Y. M., Liu, H. L., Zhao, J. H., Huang, C. H., Fang, H. W., Ho, Y. & Chen, W. Y., 五月 2007, 於 : Biotechnology Progress. 23, 3, p. 577-584 8 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Molecular dynamics simulations to investigate the effects of zinc ions on the structural stability of the c-Cbl RING domain

Liu, H. L., Yang, C. T., Zhao, J. H., Huang, C. H., Lin, H. Y., Fang, H. W., Ho, Y. & Tsai, W. B., 九月 2007, 於 : Biotechnology Progress. 23, 5, p. 1231-1238 8 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Pharmacokinetics and nephrotoxicity of aristolochic acid in rabbits

Chen, S. M., Fan, M. Y., Tseng, C. C., Ho, Y. & Hsu, K. Y., 八月 2007, 於 : Toxicon. 50, 2, p. 180-188 9 p.

研究成果: 雜誌貢獻文章

26 引文 斯高帕斯(Scopus)
2006

Structural analysis of human lysozyme using molecular dynamics simulations

Liu, H. L., Wu, Y. C., Zhao, J. H., Fang, H. W. & Ho, Y., 十二月 2006, 於 : Journal of Biomolecular Structure and Dynamics. 24, 3, p. 229-238 10 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
2005

Homology models of main proteinase from coronavirus associated with SARS

Liu, H. L., Lin, J. C., Ho, Y. & Chen, C. W., 一月 1 2005, 於 : Chemical Physics Letters. 401, 1-3, p. 24-29 6 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Molecular dynamics simulations of metal ion binding to the His-tag motif

Chen, C. W., Liu, H. L., Lin, J. C. & Ho, Y., 2005, 於 : Journal of the Chinese Chemical Society. 52, 6, p. 1281-1290 10 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)
2004

Homology models and molecular dynamics simulations of main proteinase from coronavirus associated with Severe Acute Respiratory Syndrome (SARS)

Liu, H. L., Lin, J. C., Ho, Y., Hsieh, W. C., Chen, C. W. & Su, Y. C., 2004, 於 : Journal of the Chinese Chemical Society. 51, 5 A, p. 889-900 12 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Molecular dynamics simulations of various coronavirus main proteinases

Liu, H. L., Lin, J. C., Ho, Y., Hsieh, W. C., Chen, C. W. & Su, Y. C., 八月 2004, 於 : Journal of Biomolecular Structure and Dynamics. 22, 1, p. 65-77 13 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
2003
16 引文 斯高帕斯(Scopus)

The effect of metal ions on the binding of ethanol to human alcohol dehydrogenase β2β2

Liu, H. L., Ho, Y. & Hsu, C. M., 2003, 於 : Journal of Biomedical Science. 10, 3, p. 302-312 11 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)