每年研究成果
研究成果 2009 2019
2019
Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A
Chen, J. C. H., Chuang, H. Y., Liao, Y. J., Hsu, F. T., Chen, Y. C., Wang, W. H. & Hwang, J. J., 一月 1 2019, 於 : Oncology Letters. 17, 1, p. 638-645 8 p.研究成果: 雜誌貢獻 › 文章
trichostatin A
Hepatocellular Carcinoma
Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinase Kinases
sorafenib
Ex vivo expanded human Vγ9vδ2 T-cells can suppress epithelial ovarian cancer cell growth
Mao, T. L., Miao, C. H., Liao, Y. J., Chen, Y. J., Yeh, C. Y. & Liu, C. L., 三月 1 2019, 於 : International Journal of Molecular Sciences. 20, 5, 1139.研究成果: 雜誌貢獻 › 文章
開啟存取
T-cells
Cell growth
cancer
Tumors
T-Lymphocytes
HMGCS2 mediates ketone production and regulates the proliferation and metastasis of hepatocellular carcinoma
Wang, Y. H., Liu, C. L., Chiu, W. C., Twu, Y. C. & Liao, Y. J., 十二月 2019, 於 : Cancers. 11, 12, 1876.研究成果: 雜誌貢獻 › 文章
開啟存取
Hydroxymethylglutaryl-CoA Synthase
Ketones
Hepatocellular Carcinoma
Neoplasm Metastasis
Liver Neoplasms
1
引文
(Scopus)
Respective radiation output characteristics of transmission-target and reflection-target X-ray tubes with the same beam quality
Wang, S. F., Chiang, H. Y., Liao, Y. J., Liu, R. S., Cheng, C. C., Yang, H. W., Wang, S. W., Lin, Y. C. & Hsu, S. M., 五月 1 2019, 於 : Radiation Physics and Chemistry. 158, p. 188-193 6 p.研究成果: 雜誌貢獻 › 文章
tubes
output
radiation
x rays
dosage
TGF-β regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression
Huang, C. H., Liao, Y. J., Chiou, T. J., Huang, H. T., Lin, Y. H. & Twu, Y. C., 一月 1 2019, 於 : Immunobiology.研究成果: 雜誌貢獻 › 文章
Transforming Growth Factors
Leukemia
Down-Regulation
Natural Killer Cells
Intercellular Adhesion Molecule-1
Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma
Suk, F. M., Liu, C. L., Hsu, M. H., Chuang, Y. T., Wang, J. P. & Liao, Y. J., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 17259.研究成果: 雜誌貢獻 › 文章
Hepatocellular Carcinoma
Therapeutics
Epithelial-Mesenchymal Transition
Heterografts
Glypicans
2018
2
引文
(Scopus)
AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage
Fang, C. C., Wu, C. F., Liao, Y. J., Huang, S. F., Chen, M. & Chen, Y. M. A., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 13802.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Dependovirus
Carbon Tetrachloride
Hepatocellular Carcinoma
Liver
3
引文
(Scopus)
A developed NK-92MI cell line with siglec-7neg phenotype exhibits high and sustainable cytotoxicity against leukemia cells
Huang, C. H., Liao, Y. J., Fan, T. H., Chiou, T. J., Lin, Y. H. & Twu, Y. C., 四月 4 2018, 於 : International Journal of Molecular Sciences. 19, 4, 1073.研究成果: 雜誌貢獻 › 文章
Sialic Acid Binding Immunoglobulin-like Lectins
phenotype
leukemias
Cytotoxicity
cultured cells
5
引文
(Scopus)
Niemann-pick type C2 protein regulates free cholesterol accumulation and influences hepatic stellate cell proliferation and mitochondrial respiration function
Wang, Y. H., Twu, Y. C., Wang, C. K., Lin, F. Z., Lee, C. Y. & Liao, Y. J., 六月 1 2018, 於 : International Journal of Molecular Sciences. 19, 6, 1678.研究成果: 雜誌貢獻 › 文章
Hepatic Stellate Cells
Cholesterol
cholesterol
respiration
Cell proliferation
2017
1
引文
(Scopus)
Branched I antigens on leukemia cells enhanced sensitivity against natural killer–cell cytotoxicity through affecting the target–effector interaction
Lee, Y. H., Liao, Y. J., Huang, C. H., Chang, F. L., Fan, T. H. & Twu, Y. C., 四月 1 2017, 於 : Transfusion. 57, 4, p. 1040-1051 12 p.研究成果: 雜誌貢獻 › 文章
Leukemia
Natural Killer Cells
Tumor-Associated Carbohydrate Antigens
Neoplasm Metastasis
Ligands
1
引文
(Scopus)
Characterization of a new murine cell line of sarcomatoid hepatocellular carcinoma and its application for biomarker/therapy development
Yen, C. H., Lai, C. C., Liao, C. C., Wang, S. F., Liao, Y. J., Tung, C. Y., Hung, J. H., Huang, S. F. & Chen, Y. M. A., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 3052.研究成果: 雜誌貢獻 › 文章
Hepatocellular Carcinoma
Biomarkers
Cell Line
Vimentin
Therapeutics
1
引文
(Scopus)
Feasibility study on applying radiophotoluminescent glass dosimeters for cyberknife srs dose verification
Hsu, S. M., Hung, C. H., Liao, Y. J., Fu, H. M., Tsai, J. T., Huang, Y. H. & Huang, D. Y. C., 一月 1 2017, 於 : PLoS One. 12, 1, e0169252.研究成果: 雜誌貢獻 › 文章
Dosimeters
Feasibility Studies
Dosimetry
Glass
glass
5
引文
(Scopus)
Impact of radiation attenuation by a carbon fiber couch on patient dose verification
Yu, C. Y., Chou, W. T., Liao, Y. J., Lee, J. H., Liang, J. A. & Hsu, S. M., 二月 27 2017, 於 : Scientific Reports. 7, 43336.研究成果: 雜誌貢獻 › 文章
couches
carbon fibers
attenuation
dosage
radiation
5
引文
(Scopus)
Treatment with low-dose sorafenib in combination with a novel benzimidazole derivative bearing a pyrolidine side chain provides synergistic anti-proliferative effects against human liver cancer
Hsu, M. H., Hsu, S. M., Kuo, Y. C., Liu, C. Y., Hsieh, C. Y., Twu, Y. C., Wang, C. K., Wang, Y. H. & Liao, Y. J., 2017, 於 : RSC Advances. 7, 26, p. 16253-16263 11 p.研究成果: 雜誌貢獻 › 文章
Bearings (structural)
Cell proliferation
Liver
Phosphorylation
Derivatives
2016
2
引文
(Scopus)
A volume-equivalent spherical necrosis-tumor-normal liver model for estimating absorbed dose in yttrium-90 microsphere therapy
Wu, C. H., Liao, Y. J., Lin, T. Y., Chen, C. Y., Sun, S. S., Liu, Y. W. H. & Hsu, S. M., 十一月 1 2016, 於 : Medical Physics. 43, 11, p. 6082-6088 7 p.研究成果: 雜誌貢獻 › 文章
Yttrium
Microspheres
Necrosis
Liver
Neoplasms
6
引文
(Scopus)
Design and synthesis of pyridine-pyrazole-sulfonate derivatives as potential anti-HBV agents
Chuang, H., Huang, L. C. S., Kapoor, M., Liao, Y. J., Yang, C. L., Chang, C. C., Wu, C. Y., Hwu, J. R., Huang, T. J. & Hsu, M. H., 2016, 於 : MedChemComm. 7, 5, p. 832-836 5 p.研究成果: 雜誌貢獻 › 文章
Viruses
Hepatitis B virus
Derivatives
Inhibitory Concentration 50
Nuclear magnetic resonance
5
引文
(Scopus)
Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver
Liao, Y. J., Lee, T. S., Twu, Y. C., Hsu, S. M., Yang, C. P., Wang, C. K., Liang, Y. C. & Chen, Y-M., 十月 4 2016, 於 : Journal of Biomedical Science. 23, 1, p. 1-9 9 p.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Gluconeogenesis
Phosphatidylinositol 3-Kinases
Liver
Insulin
7
引文
(Scopus)
Niemann-Pick type C2 protein mediates hepatic stellate cells activation by regulating free cholesterol accumulation
Twu, Y. C., Lee, T. S., Lin, Y. L., Hsu, S. M., Wang, Y. H., Liao, C. Y., Wang, C. K., Liang, Y. C. & Liao, Y. J., 七月 13 2016, 於 : International Journal of Molecular Sciences. 17, 7, 1122.研究成果: 雜誌貢獻 › 文章
Hepatic Stellate Cells
Cholesterol
cholesterol
Chemical activation
activation
2
引文
(Scopus)
The SHP2-ERK2 signaling pathway regulates branched I antigen formation by controlling the binding of CCAAT/enhancer binding protein α to the IGnTC promoter region during erythroid differentiation
Liao, Y. J., Lee, Y. H., Chang, F. L., Ho, H., Huang, C. H. & Twu, Y. C., 十一月 1 2016, 於 : Transfusion. 56, 11, p. 2691-2702 12 p.研究成果: 雜誌貢獻 › 文章
CCAAT-Enhancer-Binding Proteins
Genetic Promoter Regions
Phosphorylation
Surface Antigens
Granulocytes
2015
A novel simple phantom for verifying the dose of radiation therapy
Lee, J. H., Chang, L. T., Shiau, A. C., Chen, C. W., Liao, Y. J., Li, W. J., Lee, M. S. & Hsu, S. M., 2015, 於 : BioMed Research International. 2015, 934387.研究成果: 雜誌貢獻 › 文章
Radiotherapy
Dosimetry
Dosimeters
Water
Clinical Audit
HDR Brachytherapy Dose Distribution is Influenced by the Metal Material of the Applicator
Wu, C. H., Liao, Y. J., Shiau, A. C., Lin, H. Y., Hsueh Liu, Y. W. & Hsu, S. M., 十二月 11 2015, 於 : Scientific Reports. 5, 17863.研究成果: 雜誌貢獻 › 文章
Brachytherapy
Metals
Rectum
Uterine Cervical Neoplasms
Urinary Bladder
12
引文
(Scopus)
Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications
Liao, Y. J., Fang, C. C., Yen, C. H., Hsu, S. M., Wang, C. K., Huang, S. F., Liang, Y. C., Lin, Y. Y., Chu, Y. T. & Chen, Y. M. A., 九月 1 2015, 於 : International Journal of Cancer. 137, 6, p. 1341-1351 11 p.研究成果: 雜誌貢獻 › 文章
MAP Kinase Signaling System
Liver Neoplasms
Hepatocellular Carcinoma
Proteins
Cholesterol
15
引文
(Scopus)
Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase
Hou, H. H., Liao, Y. J., Hsiao, S. H., Shyue, S. K. & Lee, T. S., 八月 25 2015, 於 : Scientific Reports. 5, 13524.研究成果: 雜誌貢獻 › 文章
Epoxide Hydrolases
Simvastatin
Nitric Oxide Synthase Type III
Phosphoric Monoester Hydrolases
AMP-Activated Protein Kinases
2
引文
(Scopus)
The physical and biomedical characteristics of the novel transmission type X-ray equipment
Hsu, S. M., Wang, S. F., Hsieh, Y. J., Cheng, C. C. & Liao, Y. J., 十月 25 2015, (接受/付印) 於 : Radiation Measurements.研究成果: 雜誌貢獻 › 文章
X ray tubes
Wave transmission
Cytotoxicity
Radiation
X rays
2
引文
(Scopus)
The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients
Lin, Y. T., Yen, C. H., Chen, H. L., Liao, Y. J., Lin, I. F., Chen, M., Lan, Y. C., Chuang, S. Y., Hsieh, S. L. & Chen, Y. M. A., 六月 1 2015, 於 : Journal of the Formosan Medical Association = Taiwan yi zhi. 114, 6, p. 498-503 6 p.研究成果: 雜誌貢獻 › 文章
Disease Progression
HIV-1
Acquired Immunodeficiency Syndrome
Fas Ligand Protein
Tumor Necrosis Factor Receptors
2014
3
引文
(Scopus)
Dose distributions of an 192Ir brachytherapy source in different media
Wu, C. H., Liao, Y. J., Liu, Y. W. H., Hung, S. K., Lee, M. S. & Hsu, S. M., 2014, 於 : BioMed Research International. 2014, 946213.研究成果: 雜誌貢獻 › 文章
Brachytherapy
Lung
Tissue
Anisotropy
Water
2
引文
(Scopus)
Influence of metal of the applicator on the dose distribution during brachytherapy
Wu, C. H., Shiau, A. C., Liao, Y. J., Lin, H. Y., Liu, Y. W. H. & Hsu, S. M., 八月 18 2014, 於 : PLoS One. 9, 8, e104831.研究成果: 雜誌貢獻 › 文章
Applicators
Brachytherapy
Metals
metals
Planning
2013
8
引文
(Scopus)
Characterization of Niemann-Pick Type C2 Protein Expression in Multiple Cancers Using a Novel NPC2 Monoclonal Antibody
Liao, Y. J., Lin, M. W., Yen, C. H., Lin, Y. T., Wang, C. K., Huang, S. F., Chen, K. H., Yang, C. P., Chen, T. L., Hou, M. F. & Arthur Chen, Y. M., 十月 17 2013, 於 : PLoS One. 8, 10, e77586.研究成果: 雜誌貢獻 › 文章
Liver
liver neoplasms
monoclonal antibodies
Liver Neoplasms
protein synthesis
7
引文
(Scopus)
Identification of FKBP11 as a biomarker for hepatocellular carcinoma
Lin, I. Y., Yen, C. H., Liao, Y. J., Lin, S-E., Ma, H. P., Chan, Y. J. & Chen, Y. M. A., 六月 2013, 於 : Anticancer Research. 33, 6, p. 2763-2770 8 p.研究成果: 雜誌貢獻 › 文章
Tacrolimus Binding Proteins
Glycine N-Methyltransferase
Hepatocellular Carcinoma
Biomarkers
Knockout Mice
2012
8
引文
(Scopus)
A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source
Hsu, S. M., Wu, C. H., Lee, J. H., Hsieh, Y. J., Yu, C. Y., Liao, Y. J., Kuo, L. C., Liang, J. A. & Huang, D. Y. C., 九月 5 2012, 於 : PLoS One. 7, 9, e44528.研究成果: 雜誌貢獻 › 文章
Brachytherapy
Bone
lungs
bones
Water
16
引文
(Scopus)
Deficiency of Glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice
Chen, C. Y., Ching, L. C., Liao, Y. J., Yu, Y. B., Tsou, C. Y., Shyue, S. K., Chen, Y. M. A. & Lee, T. S., 五月 2012, 於 : Molecular Medicine. 18, 5, p. 744-752 9 p.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Apolipoproteins E
Atherosclerosis
Macrophages
Cholesterol
33
引文
(Scopus)
Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis.
Liao, Y. J., Chen, T. L., Lee, T. S., Wang, H. A., Wang, C. K., Liao, L. Y., Liu, R. S., Huang, S. F. & Chen, Y. M. A., 2012, 於 : Molecular Medicine. 18, 1, p. 412-422 11 p.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Protein Stability
Homeostasis
Cholesterol
Liver
2011
5
引文
(Scopus)
Dose measurements for gamma knife with radiophotoluminescent glass dosemeter and radiochromic film
Hsu, S. M., Lee, J. H., Hsu, F. Y., Lee, H. W., Hung, S. K., Liao, Y. J. & Lee, M. S., 七月 2011, 於 : Radiation Protection Dosimetry. 146, 1-3, p. 256-259 4 p., ncr164.研究成果: 雜誌貢獻 › 文章
Glass
Head Protective Devices
dosage
Radiosurgery
glass
17
引文
(Scopus)
Higher susceptibility to aflatoxin B1-related hepatocellular carcinoma in glycine N-methyltransferase knockout mice
Liu, S. P., Li, Y. S., Lee, C. M., Yen, C. H., Liao, Y. J., Huang, S. F., Chien, C. H. & Chen, Y. M. A., 二月 1 2011, 於 : International Journal of Cancer. 128, 3, p. 511-523 13 p.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Aflatoxin B1
Knockout Mice
Hepatocellular Carcinoma
Carcinogenesis
11
引文
(Scopus)
Radiation characteristics of homemade radiophotoluminescent glass dosimeter
Lee, M. S., Liao, Y. J., Huang, Y. H., Lee, J. H., Hung, S. K., Chen, T. R. & Hsu, S. M., 十二月 2011, 於 : Radiation Measurements. 46, 12, p. 1477-1479 3 p.研究成果: 雜誌貢獻 › 文章
Dosimeters
dosimeters
Radiation
Glass
glass
2010
1
引文
(Scopus)
Chemical and physical characteristics of self-fabricated radiophotoluminescent glass dosimeter
Hsu, S. M., Yang, H. W., Huang, Y. H., Lee, J. H., Yu, C. Y., Liao, Y. J., Hung, S. K. & Lee, M. S., 三月 2010, 於 : Radiation Measurements. 45, 3-6, p. 553-555 3 p.研究成果: 雜誌貢獻 › 文章
Dosimeters
dosimeters
Glass
glass
chemical compounds
14
引文
(Scopus)
Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver
Liao, Y. J., Chen, K. H., Huang, S. F., Chen, T. L., Wang, C. K., Chien, C. H., Tsai, T. F., Liu, S. P. & Chen, Y. M. A., 四月 2010, 於 : Proteomics - Clinical Applications. 4, 4, p. 394-406 13 p.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Knockout Mice
Liver
Deterioration
Detoxification
2009
63
引文
(Scopus)
Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility
Liao, Y. J., Liu, S. P., Lee, C. M., Yen, C. H., Chuang, P. C., Chen, C. Y., Tsai, T. F., Huang, S. F., Lee, Y. H. W. & Chen, Y. M. A., 二月 15 2009, 於 : International Journal of Cancer. 124, 4, p. 816-826 11 p.研究成果: 雜誌貢獻 › 文章
Glycine N-Methyltransferase
Gene Knockout Techniques
Liver Neoplasms
Knockout Mice
Hepatocellular Carcinoma