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研究成果 2003 2019

2019
3 引文 (Scopus)

Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer

Chen, W. Y., Zeng, T., Wen, Y. C., Yeh, H. L., Jiang, K. C., Chen, W. H., Zhang, Q., Huang, J. & Liu, Y. N., 一月 1 2019, 於 : Cancer Letters. 440-441, p. 35-46 12 p.

研究成果: 雜誌貢獻文章

Prostaglandin-Endoperoxide Synthases
Androgens
Prostatic Neoplasms
Cyclooxygenase Inhibitors
Androgen Receptors
1 引文 (Scopus)

Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46

Liu, Y-N., Niu, S., Chen, W-Y., Zhang, Q., Tao, Y., Chen, W-H., Jiang, K-C., Chen, X., Shi, H., Liu, A., Li, J., Li, Y., Lee, Y-C., Zhang, X. & Huang, J., 四月 8 2019, 於 : Clinical cancer research : an official journal of the American Association for Cancer Research.

研究成果: 雜誌貢獻文章

Leukemia Inhibitory Factor
Castration
Prostatic Neoplasms
Androgens
Therapeutics
2 引文 (Scopus)

RAB14 activates MARK signaling to promote bladder tumorigenesis

Chao, H., Deng, L., Xu, F., Fu, B., Zhu, Z., Dong, Z., Liu, Y-N. & Zeng, T., 二月 27 2019, 於 : Carcinogenesis.

研究成果: 雜誌貢獻文章

Urinary Bladder Neoplasms
Carcinogenesis
Urinary Bladder
Mitogen-Activated Protein Kinases
Twist-Related Protein 1
1 引文 (Scopus)

The synthetic retinoid ST1926 attenuates prostate cancer growth and potentially targets prostate cancer stem-like cells

Bahmad, H. F., Samman, H., Monzer, A., Hadadeh, O., Cheaito, K., Abdel-Samad, R., Hayar, B., Pisano, C., Msheik, H., Liu, Y-N., Darwiche, N. & Abou-Kheir, W., 七月 2019, 於 : Molecular Carcinogenesis. 58, 7, p. 1208-1220 13 p.

研究成果: 雜誌貢獻文章

Neoplastic Stem Cells
Retinoids
Prostatic Neoplasms
Growth
Apoptosis
1 引文 (Scopus)
開啟存取
biomarkers
Castration
Androgen Receptors
Biomarkers
Prostatic Neoplasms
2018
4 引文 (Scopus)
Activating Transcription Factors
CC Chemokines
Epithelial-Mesenchymal Transition
Androgens
Prostatic Neoplasms
2 引文 (Scopus)

Correction: Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance [Oncotarget. 5, (2014), 3770-3784]doi 10.18632/oncotarget.1994

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., 八月 17 2018, 於 : Oncotarget. 9, 64, p. 32403 1 p.

研究成果: 雜誌貢獻評論/辯論

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Medicine
Neoplasm Metastasis
1 引文 (Scopus)
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Prostatic Neoplasms
Genes
Castration
12 引文 (Scopus)

MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB

Niu, S., Ma, X., Zhang, Y., Liu, Y. N., Chen, X., Gong, H., Yao, Y., Liu, K. & Zhang, X., 二月 1 2018, 於 : PLoS One. 13, 2, e0192790.

研究成果: 雜誌貢獻文章

kidney cells
MicroRNAs
microRNA
Renal Cell Carcinoma
carcinoma
11 引文 (Scopus)

Sphere-Formation Assay: Three-dimensional in vitro culturing of prostate cancer stem/Progenitor sphere-forming cells

Bahmad, H. F., Cheaito, K., Chalhoub, R. M., Hadadeh, O., Monzer, A., Ballout, F., El-Hajj, A., Mukherji, D., Liu, Y. N., Daoud, G. & Abou-Kheir, W., 八月 28 2018, 於 : Frontiers in Oncology. 8, AUG, 347.

研究成果: 雜誌貢獻文章

Neoplastic Stem Cells
Prostatic Neoplasms
Neoplasms
Castration
In Vitro Techniques
2017
9 引文 (Scopus)

ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis

Chiu, K. L., Lin, Y. S., Kuo, T. T., Lo, C. C., Huang, Y. K., Chang, H. F., Chuang, E. Y., Lin, C. C., Cheng, W. C., Liu, Y. N., Lai, L. C. & Sher, Y. P., 2017, 於 : Oncotarget. 8, 29, p. 47365-47378 14 p.

研究成果: 雜誌貢獻文章

Disintegrins
Metalloproteases
Lung Neoplasms
Neoplasm Metastasis
MicroRNAs
10 引文 (Scopus)
MicroRNAs
Epidermal Growth Factor Receptor
Prostatic Neoplasms
Down-Regulation
Neoplasms
10 引文 (Scopus)

Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis

Chen, W-Y., Tsai, Y-C., Siu, M. K., Yeh, H-L., Chen, C-L., Yin, J. J., Huang, J. & Liu, Y-N., 七月 10 2017, 於 : Oncogene. p. 6213-6224

研究成果: 雜誌貢獻文章

Androgen Receptors
Carcinogens
Prostatic Neoplasms
Neoplasm Metastasis
Epithelial-Mesenchymal Transition
18 引文 (Scopus)

Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer

Chen, W. Y., Tsai, Y. C., Yeh, H. L., Suau, F., Jiang, K. C., Shao, A. N., Huang, J. & Liu, Y. N., 八月 15 2017, 於 : Science Signaling. 10, 492, eaam6826.

研究成果: 雜誌貢獻文章

Epithelial-Mesenchymal Transition
Androgens
Prostatic Neoplasms
Bone
Androgen Receptors
5 引文 (Scopus)

MiR-96 expression in prostate cancer and its effect on the target gene regulation

Bao, Y. H., Wang, Y., Liu, Y., Wang, S. & Wu, B., 十月 1 2017, 於 : European Review for Medical and Pharmacological Sciences. 21, 20, p. 4548-4556 9 p.

研究成果: 雜誌貢獻文章

Prostatic Neoplasms
Genes
Small Interfering RNA
Transfection
Western Blotting

New ideas in preventing castration-resistant prostate cancer

Tsai, Y. C. & Liu, Y. N., 十月 17 2017, 於 : Oncotarget. 8, 49, p. 84628-84629 2 p.

研究成果: 雜誌貢獻社論

Epithelial-Mesenchymal Transition
Castration
Integrins
Prostatic Neoplasms
8 引文 (Scopus)
T Cell Transcription Factor 1
Androgen Receptors
MicroRNAs
Androgens
Prostatic Neoplasms
6 引文 (Scopus)

Androgen receptor regulates SRC expression through microRNA-203

Siu, M. K., Chen, W. Y., Tsai, H. Y., Yeh, H. L., Yin, J. J., Liu, S. Y. & Liu, Y-N., 五月 1 2016, 於 : Oncotarget. 7, 18, p. 25726-25741 16 p.

研究成果: 雜誌貢獻文章

Androgen Receptors
MicroRNAs
Prostatic Neoplasms
RNA Stability
3' Untranslated Regions

KLF4 functions as an activator of the androgen receptor through reciprocal feedback

Siu, M-K., Suau, F., Chen, W-Y., Tsai, Y-C., Tsai, H-Y., Yeh, H-L. & Liu, Y-N., 十二月 2016, 於 : Oncogenesis. 5, 12, p. e282

研究成果: 雜誌貢獻文章

Activator Appliances
Androgen Receptors
MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
5 引文 (Scopus)

Primary versus castration-resistant prostate cancer: Modeling through novel murine prostate cancer cell line

Daoud, G., Monzer, A., Bahmad, H., Chamaa, F., Hamdar, L., Mouhieddine, T. H., Shayya, S., Eid, A., Kobeissy, F., Liu, Y. N. & Abou-Kheir, W., 五月 17 2016, 於 : Oncotarget. 7, 20, p. 28961-28975 15 p.

研究成果: 雜誌貢獻文章

Castration
Androgens
Prostatic Neoplasms
Cell Line
Neoplasm Invasiveness
2015
9 引文 (Scopus)
Nicotinic Receptors
Fluorouracil
Stomach Neoplasms
In Situ Nick-End Labeling
Cell Cycle
59 引文 (Scopus)

EGF receptor promotes prostate cancer bone metastasis by downregulating miR-1 and activating TWIST1

Chang, Y. S., Chen, W. Y., Yin, J. J., Sheppard-Tillman, H., Huang, J. & Liu, Y. N., 八月 1 2015, 於 : Cancer Research. 75, 15, p. 3077-3086 10 p.

研究成果: 雜誌貢獻文章

Bone Neoplasms
Epidermal Growth Factor Receptor
Prostatic Neoplasms
Down-Regulation
Neoplasm Metastasis
30 引文 (Scopus)

Loss of androgen-regulated MicroRNA 1 activates SRC and promotes prostate cancer bone metastasis

Liu, Y. N., Yin, J., Barrett, B., Sheppard-Tillman, H., Li, D., Casey, O. M., Fang, L., Hynes, P. G., Ameri, A. H. & Kelly, K., 2015, 於 : Molecular and Cellular Biology. 35, 11, p. 1940-1951 12 p.

研究成果: 雜誌貢獻文章

Bone Neoplasms
MicroRNAs
Androgens
Prostatic Neoplasms
Neoplasm Metastasis
64 引文 (Scopus)

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer

Chen, W. Y., Liu, S. Y., Chang, Y. S., Yin, J. J., Yeh, H. L., Mouhieddine, T. H., Hadadeh, O., Abou-Kheir, W. & Liu, Y. N., 2015, 於 : Oncotarget. 6, 1, p. 441-457 17 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
3' Untranslated Regions
50 引文 (Scopus)

Transforming growth factor-β promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway

Siu, M. K., Tsai, Y. C., Chang, Y. S., Yin, J. J., Suau, F., Chen, W. Y. & Liu, Y. N., 九月 3 2015, 於 : Oncogene. 34, 36, p. 4767-4776 10 p.

研究成果: 雜誌貢獻文章

Transforming Growth Factors
Sirolimus
MicroRNAs
Prostate
Neoplasm Metastasis
2014
20 引文 (Scopus)

AR-regulated TWEAK-FN14 pathway promotes prostate cancer bone metastasis

Yin, J., Liu, Y. N., Tillman, H., Barrett, B., Hewitt, S., Ylaya, K., Fang, L., Lake, R., Corey, E., Morrissey, C., Vessella, R. & Kelly, K., 八月 15 2014, 於 : Cancer Research. 74, 16, p. 4306-4317 12 p.

研究成果: 雜誌貢獻文章

Bone Neoplasms
Androgen Receptors
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
24 引文 (Scopus)

Berberis libanotica ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells

El-Merahbi, R., Liu, Y. N., Eid, A., Daoud, G., Hosry, L., Monzer, A., Mouhieddine, T. H., Hamade, A., Najjar, F. & Abou-Kheir, W., 十一月 7 2014, 於 : PLoS One. 9, 11, e112453.

研究成果: 雜誌貢獻文章

Berberis
Neoplastic Stem Cells
prostatic neoplasms
Stem cells
stem cells
Protein-Tyrosine Kinases
Prostatic Neoplasms
Up-Regulation
Bone and Bones
Apoptosis Regulatory Proteins
36 引文 (Scopus)

Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., 2014, 於 : Oncotarget. 5, 11, p. 3770-3784 15 p.

研究成果: 雜誌貢獻文章

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Neoplasm Metastasis
Apoptosis Regulatory Proteins
2013
188 引文 (Scopus)

MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms

Liu, Y. N., Yin, J. J., Abou-Kheir, W., Hynes, P. G., Casey, O. M., Fang, L., Yi, M., Stephens, R. M., Seng, V., Sheppard-Tillman, H., Martin, P. & Kelly, K., 一月 17 2013, 於 : Oncogene. 32, 3, p. 296-306 11 p.

研究成果: 雜誌貢獻文章

Gastropoda
Epithelial-Mesenchymal Transition
Carcinogenesis
Prostate
MicroRNAs
2012
100 引文 (Scopus)

Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition

Liu, Y. N., Abou-Kheir, W., Yin, J. J., Fang, L., Hynes, P., Casey, O., Hu, D., Wan, Y., Seng, V., Sheppard-Tillman, H., Martin, P. & Kelly, K., 三月 2012, 於 : Molecular and Cellular Biology. 32, 5, p. 941-953 13 p.

研究成果: 雜誌貢獻文章

Epithelial-Mesenchymal Transition
Transforming Growth Factors
Prostatic Neoplasms
Prostate
Tissue Array Analysis
2011
48 引文 (Scopus)

Prostate epithelial PTEN/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition

Martin, P., Liu, Y. N., Pierce, R., Abou-Kheir, W., Casey, O., Seng, V., Camacho, D., Simpson, R. M. & Kelly, K., 七月 2011, 於 : American Journal of Pathology. 179, 1, p. 422-435 14 p.

研究成果: 雜誌貢獻文章

Epithelial-Mesenchymal Transition
Prostate
Neoplasms
Carcinoma
Prostatic Neoplasms
17 引文 (Scopus)

Self-renewing Pten -/-TP53 -/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity

Abou-Kheir, W., Hynes, P. G., Martin, P., Yin, J. J., Liu, Y. N., Seng, V., Lake, R., Spurrier, J. & Kelly, K., 十月 11 2011, 於 : PLoS One. 6, 10, e26112.

研究成果: 雜誌貢獻文章

prostatic neoplasms
adenocarcinoma
stem cells
Tumors
Adenocarcinoma
2008
82 引文 (Scopus)

Activated androgen receptor downregulates E-cadherin gene expression and promotes tumor metastasis

Liu, Y. N., Liu, Y., Lee, H. J., Hsu, Y. H. & Chen, J. H., 十二月 2008, 於 : Molecular and Cellular Biology. 28, 23, p. 7096-7108 13 p.

研究成果: 雜誌貢獻文章

Androgen Receptors
Cadherins
Down-Regulation
Neoplasm Metastasis
Gene Expression
2005
136 引文 (Scopus)

Regulatory mechanisms controlling human E-cadherin gene expression

Liu, Y. N., Lee, W. W., Wang, C. Y., Chao, T. H., Chen, Y. & Ji, H. C., 十二月 15 2005, 於 : Oncogene. 24, 56, p. 8277-8290 14 p.

研究成果: 雜誌貢獻文章

Cadherins
Gene Expression
Breast Neoplasms
Up-Regulation
Neoplasms
2004
28 引文 (Scopus)

Transcriptional regulation of human osteopontin promoter by C/EBPα and AML-1 in metastatic cancer cells

Liu, Y. N., Kang, B. B. & Chen, J. H., 一月 8 2004, 於 : Oncogene. 23, 1, p. 278-288 11 p.

研究成果: 雜誌貢獻文章

CCAAT-Enhancer-Binding Protein-alpha
Osteopontin
Neoplasms
Protein Binding
Transcriptional Activation
2003
49 引文 (Scopus)

Trans-activation of heparanase promoter by ETS transcription factors

Lu, W. C., Liu, Y. N., Kang, B. B. & Chen, J. H., 二月 13 2003, 於 : Oncogene. 22, 6, p. 919-923 5 p.

研究成果: 雜誌貢獻文章

Transcription Factors
Extracellular Matrix
Neoplasms
Transcriptional Activation
Genes