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研究成果 1984 2019

  • 8168 引文
  • 48 h-指數
  • 141 文章
  • 1 章節
2019

Folic acid inhibits colorectal cancer cell migration

Ting, P. C., Lee, W. R., Huo, Y. N., Hsu, S. P. & Lee, W. S., 一月 1 2019, 於 : Journal of Nutritional Biochemistry. 63, p. 157-164 8 p.

研究成果: 雜誌貢獻文章

Folic Acid
Cell Movement
Colorectal Neoplasms
Cells
Cell proliferation
2018
2 引文 (Scopus)

Effects of female sex hormones on folic acid-induced anti-angiogenesis

Lee, W. S., Lu, Y. C., Kuo, C. T., Chen, C. T. & Tang, P. H., 一月 1 2018, (接受/付印) 於 : Acta Physiologica.

研究成果: 雜誌貢獻文章

Gonadal Steroid Hormones
Folic Acid
Umbilicus
Endothelial Cells
Estradiol Receptors
2 引文 (Scopus)

Intermittent hypoxia-generated ROS contributes to intracellular zinc regulation that limits ischemia/reperfusion injury in adult rat cardiomyocyte

Lien, C. F., Lee, W. S., Wang, I. C., Chen, T. I., Chen, T. L. & Yang, K. T., 五月 1 2018, 於 : Journal of Molecular and Cellular Cardiology. 118, p. 122-132 11 p.

研究成果: 雜誌貢獻文章

Reperfusion Injury
Cardiac Myocytes
Zinc
Reperfusion
Ischemia
2 引文 (Scopus)
Phosphorylation
Cell proliferation
Progesterone
Stathmin
Cells
2 引文 (Scopus)

PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1

Wen, H. C., Huo, Y. N., Chou, C. M. & Lee, W. S., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 16247.

研究成果: 雜誌貢獻文章

Cell Movement
Acetates
Up-Regulation
Endothelial Cells
phorbol-12-myristate
Endothelial cells
Human Umbilical Vein Endothelial Cells
Progesterone
Up-Regulation
Protein Binding
2016
7 引文 (Scopus)

Molecular mechanisms underlying progesterone-enhanced breast cancer cell migration

Wang, H. C. & Lee, W. S., 八月 11 2016, 於 : Scientific Reports. 6, 31509.

研究成果: 雜誌貢獻文章

Cell Movement
Progesterone
Breast Neoplasms
Vascular Smooth Muscle
Smooth Muscle Myocytes
6 引文 (Scopus)

Progesterone receptor activation is required for folic acid-induced anti-proliferation in colorectal cancer cell lines

Kuo, C. T. & Lee, W. S., 八月 10 2016, 於 : Cancer Letters. 378, 2, p. 104-110 7 p.

研究成果: 雜誌貢獻文章

Progesterone Receptors
Folic Acid
Colorectal Neoplasms
Cell Line
Colonic Neoplasms
2015
8 引文 (Scopus)
smooth muscle
myocytes
Smooth Muscle Myocytes
Progesterone
Muscle
13 引文 (Scopus)
Folate Receptor 1
Folic Acid
Colonic Neoplasms
Cyclin-Dependent Kinase Inhibitor p27
Cell Proliferation
16 引文 (Scopus)
Mitochondrial Degradation
Mitochondrial Dynamics
Bovine Serum Albumin
Thioctic Acid
Insulin
11 引文 (Scopus)

Progesterone inhibits endothelial cell migration through suppression of the rho activity mediated by csrc activation

Lee, T. S., Lin, J. J., Huo, Y. N. & Lee, W. S., 七月 1 2015, 於 : Journal of Cellular Biochemistry. 116, 7, p. 1411-1418 8 p.

研究成果: 雜誌貢獻文章

Umbilicus
Endothelial cells
Cell Movement
Progesterone
Endothelial Cells
5 引文 (Scopus)

Progesterone receptor-nfκb complex formation is required for progesterone-induced nfκb nuclear translocation and binding onto the p53 promoter

Hsu, S. P., Yang, H. C., Kuo, C. T., Wen, H. C., Chen, L. C., Huo, Y. N. & Lee, W. S., 一月 1 2015, 於 : Endocrinology. 156, 1, p. 291-300 10 p.

研究成果: 雜誌貢獻文章

Umbilicus
Progesterone Receptors
Progesterone
Endothelial Cells
Cytoplasmic and Nuclear Receptors
2014
7 引文 (Scopus)
Smooth Muscle Myocytes
Progesterone
Up-Regulation
ras Genes
Inhibition (Psychology)
6 引文 (Scopus)

Progesterone induces RhoA inactivation in male rat aortic smooth muscle cells through up-regulation of p27kip1

Wang, H. C. & Lee, W. S., 十一月 1 2014, 於 : Endocrinology. 155, 11, p. 4473-4482 10 p.

研究成果: 雜誌貢獻文章

Smooth Muscle Myocytes
Progesterone
Up-Regulation
Stathmin
Phosphotransferases
2013
5 引文 (Scopus)
NF-kappa B
Endothelial cells
transcriptional activation
citrates
Estrogen Receptors
25 引文 (Scopus)
Endothelial cells
Folic Acid
Cell Movement
Endothelial Cells
Umbilicus
5 引文 (Scopus)
Homocysteine
Folic Acid
Smooth Muscle Myocytes
Focal Adhesion Protein-Tyrosine Kinases
Transfection
19 引文 (Scopus)
apoptosis
Apoptosis
mitogen-activated protein kinase
p38 Mitogen-Activated Protein Kinases
Biphenyl Compounds
1 引文 (Scopus)

Thy-1-Induced Migration Inhibition in Vascular Endothelial Cells through Reducing the RhoA Activity

Wen, H. C., Kao, C., Hsu, R. C., Huo, Y. N., Ting, P. C., Chen, L. C., Hsu, S. P., Juan, S. H. & Lee, W. S., 四月 17 2013, 於 : PLoS One. 8, 4, e61506.

研究成果: 雜誌貢獻文章

Endothelial cells
Human Umbilical Vein Endothelial Cells
blood vessels
endothelial cells
transfection
2012
46 引文 (Scopus)

Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity

Chien, M. H., Ying, T. H., Hsieh, Y. S., Chang, Y. C., Yeh, C. M., Ko, J. L., Lee, W. S., Chang, J. H. & Yang, S. F., 三月 2012, 於 : Food and Chemical Toxicology. 50, 3-4, p. 558-566 9 p.

研究成果: 雜誌貢獻文章

Dioscorea nipponica
Dioscorea
Cyclic AMP Response Element-Binding Protein
gelatinase A
response elements
9 引文 (Scopus)
Endothelial cells
Nitric Oxide Synthase
citrates
endothelial cells
Free Radicals
28 引文 (Scopus)

Folic acid inhibits endothelial cell proliferation through activating the cSrc/ERK 2/NF-jB/p53 pathway mediated by folic acid receptor

Lin, S. Y., Lee, W. R., Su, Y. F., Hsu, S. P., Lin, H. C., Ho, P. Y., Hou, T. C., Chou, Y. P., Kuo, C. T. & Lee, W. S., 2012, 於 : Angiogenesis. 15, 4, p. 671-683 13 p.

研究成果: 雜誌貢獻文章

Endothelial cells
Cell proliferation
Folic Acid
Endothelial Cells
Cell Proliferation
35 引文 (Scopus)

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway

Chen, L. C., Tu, S. H., Huang, C. S., Chen, C. S., Ho, C. T., Lin, H. W., Lee, C. H., Chang, H. W., Chang, C. H., Wu, C. H., Lee, W. S. & Ho, Y. S., 八月 2012, 於 : Breast Cancer Research and Treatment. 134, 3, p. 989-1004 16 p.

研究成果: 雜誌貢獻文章

Protein-Lysine 6-Oxidase
Paxillin
Focal Adhesion Protein-Tyrosine Kinases
Down-Regulation
Breast Neoplasms
30 引文 (Scopus)

Inhibition of autophagy as a therapeutic strategy of iron-induced brain injury after hemorrhage

Chen, C. W., Chen, T. Y., Tsai, K. L., Lin, C. L., Yokoyama, K. K., Lee, W. S., Chiueh, C. C. & Hsu, C., 十月 2012, 於 : Autophagy. 8, 10, p. 1510-1520 11 p.

研究成果: 雜誌貢獻文章

Autophagy
Brain Injuries
Iron
Hemorrhage
Caudate Nucleus
Subarachnoid Hemorrhage
Brain Injuries
Estradiol
Intracranial Vasospasm
Nitric Oxide Synthase Type II
3 引文 (Scopus)

Putative tumor metastasis-associated genes in human gastric cancer

Tuan, T. F., Chung, C. T., Tsou, H. H., Chen, F. W., Lin, H. L., Lai, Y. K., Lee, W. S., Chao, Y. S., Hwang, L. L. & Chen, C. T., 九月 2012, 於 : International Journal of Oncology. 41, 3, p. 1068-1084 17 p.

研究成果: 雜誌貢獻文章

Stomach Neoplasms
Neoplasm Metastasis
Genes
Neoplasms
Liver
11 引文 (Scopus)

Terbinafine inhibits oral squamous cell carcinoma growth through anti-cancer cell proliferation and anti-angiogenesis

Chien, M. H., Lee, T. S., Kao, C., Yang, S. F. & Lee, W. S., 五月 2012, 於 : Molecular Carcinogenesis. 51, 5, p. 389-399 11 p.

研究成果: 雜誌貢獻文章

terbinafine
Squamous Cell Carcinoma
Cell Proliferation
Growth
Neoplasms
2011
13 引文 (Scopus)

Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration

Hsu, S. P., Chen, T. H., Chou, Y. P., Chen, L. C., Kuo, C. T., Lee, T. S., Lin, J. J., Chang, N. C. & Lee, W. S., 七月 2011, 於 : Atherosclerosis. 217, 1, p. 83-89 7 p.

研究成果: 雜誌貢獻文章

Progesterone Receptors
Smooth Muscle Myocytes
Cell Movement
rhoA GTP-Binding Protein
Cell Migration Inhibition
26 引文 (Scopus)
Lovastatin
Up-Regulation
Cells
Cyclin A2
Cyclin D3
15 引文 (Scopus)
Antrodia
Taiwanofungus camphoratus
amphotericin B
Amphotericin B
cytotoxicity
23 引文 (Scopus)
Human Umbilical Vein Endothelial Cells
Progesterone Receptors
Endothelial Cells
Up-Regulation
src-Family Kinases
2010
6 引文 (Scopus)
Colonic Neoplasms
Apoptosis
Cell Line
DNA
Cell Cycle Proteins
6 引文 (Scopus)

Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type

Tuan, T. F., Tsai, M. L., Yeh, K. C., Huang, H. C., Chung, C. T., Huang, C. L., Han, C. H., Chen, C. P., Wang, M. H., Shen, C. C., Lai, Y. K., Lee, W-S., Hwang, L-L. & Chen, C. T., 九月 2010, 於 : Current Microbiology. 61, 4, p. 773-783 11 p.

研究成果: 雜誌貢獻文章

Paclitaxel
Green Fluorescent Proteins
Stomach
Stomach Neoplasms
Neoplasm Metastasis
23 引文 (Scopus)

Sex-specific role of thioredoxin in neuroprotection against iron-induced brain injury conferred by estradiol

Chen, T. Y., Tsai, K. L., Lee, T. Y., Chiueh, C. C., Lee, W. S. & Hsu, C., 一月 2010, 於 : Stroke. 41, 1, p. 160-165 6 p.

研究成果: 雜誌貢獻文章

Thioredoxins
Brain Injuries
Estradiol
Iron
Caudate Nucleus
5 引文 (Scopus)
sitosterols
smooth muscle
myocytes
Smooth Muscle Myocytes
Muscle
2009
4 引文 (Scopus)
Mitogen-Activated Protein Kinase 3
Cyclooxygenase 2
Cyclic GMP-Dependent Protein Kinases
Epithelial Cells
Lung
3 引文 (Scopus)
terbinafine
JNK Mitogen-Activated Protein Kinases
Endothelial cells
Umbilicus
Up-Regulation
41 引文 (Scopus)
Cell proliferation
Glioblastoma
cell proliferation
Up-Regulation
Cell Proliferation
2008
13 引文 (Scopus)

Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10)

Liu, Y., Wu, J., Ho, P. Y., Chen, L. C., Chen, C. T., Liang, Y. C., Cheng, C. K. & Lee, W. S., 十一月 28 2008, 於 : Cancer Letters. 271, 2, p. 294-305 12 p.

研究成果: 雜誌貢獻文章

Human Umbilical Vein Endothelial Cells
Thiohydantoins
Thymidine
Phosphotransferases
Cell Cycle
10 引文 (Scopus)
terbinafine
Phosphorylation
Extracellular Signal-Regulated MAP Kinases
Endothelial cells
Up-Regulation
34 引文 (Scopus)

Neuronal activity enhances aryl hydrocarbon receptor-mediated gene expression and dioxin neurotoxicity in cortical neurons

Lin, C. H., Juan, S. H., Wang, C. Y., Sun, Y. Y., Chou, C. M., Chang, S. F., Hu, S. Y., Lee, W. S. & Lee, Y-H., 三月 2008, 於 : Journal of Neurochemistry. 104, 5, p. 1415-1429 15 p.

研究成果: 雜誌貢獻文章

Aryl Hydrocarbon Receptors
Dioxins
Gene expression
Neurons
Gene Expression
25 引文 (Scopus)

NF-κB-activated tissue transglutaminase is involved in ethanol-induced hepatic injury and the possible role of propolis in preventing fibrogenesis

Chen, C. S., Wu, C. H., Lai, Y. C., Lee, W. S., Chen, H. M., Chen, R. J., Chen, L. C., Ho, Y. S. & Wang, Y. J., 四月 18 2008, 於 : Toxicology. 246, 2-3, p. 148-157 10 p.

研究成果: 雜誌貢獻文章

Propolis
Ethanol
Liver
Wounds and Injuries
Liver Cirrhosis
20 引文 (Scopus)
Progesterone
Endothelial Cells
Cell Proliferation
Human Umbilical Vein Endothelial Cells
Thymidine
11 引文 (Scopus)
terbinafine
Gene expression
Tumors
Cell Differentiation
Cells
8 引文 (Scopus)

Structure and anti-proliferation function of 5,5-diphenyl-2-thiohydantoin (DPTH) derivatives in vascular endothelial cells

Cheng, C. K., Wu, J., Liu, Y., Lee, T. S., Kang, S. J., Sheu, M. T. & Lee, W. S., 二月 2008, 於 : Vascular Pharmacology. 48, 2-3, p. 138-142 5 p.

研究成果: 雜誌貢獻文章

Umbilicus
Endothelial Cells
Phenytoin
Cell Cycle
Cyclin-Dependent Kinase 2
2007
1 引文 (Scopus)

Endothelial Cell Proliferation Assays

Lee, W. S., 九月 27 2007, Angiogenesis Assays: A Critical Appraisal of Current Techniques. John Wiley & Sons, Ltd, p. 39-50 12 p.

研究成果: 書貢獻/報告類型章節

Endothelial cells
Cell proliferation
Assays
Endothelial Cells
Cell Proliferation
37 引文 (Scopus)

Involvement of Ras/Raf-1/ERK actions in the magnolol-induced upregulation of p21 and cell-cycle arrest in colon cancer cells

Hsu, Y. F., Lee, T. S., Lin, S. Y., Hsu, S. P., Juan, S. H., Hsu, Y. N., Zhong, W. B. & Lee, W. S., 四月 2007, 於 : Molecular Carcinogenesis. 46, 4, p. 275-283 9 p.

研究成果: 雜誌貢獻文章

Mitogen-Activated Protein Kinase 3
Cell Cycle Checkpoints
Colonic Neoplasms
Up-Regulation
Extracellular Signal-Regulated MAP Kinases
3 引文 (Scopus)

The molecular events occur during MK-801-induced cytochrome oxidase subunit II down-regulation in GT1-7 cells

Lee, T. Y., Tsai, K. L., Lee, W. S. & Hsu, C., 七月 2007, 於 : Journal of Molecular Endocrinology. 39, 1-2, p. 53-66 14 p.

研究成果: 雜誌貢獻文章

Dizocilpine Maleate
Electron Transport Complex IV
N-Methyl-D-Aspartate Receptors
Down-Regulation
Apoptosis
2006
32 引文 (Scopus)

17β-Estradiol inhibits subarachnoid hemorrhage-induced inducible nitric oxide synthase gene expression by interfering with the nuclear factor κB transactivation

Shih, H. C., Lin, C. L., Lee, T. Y., Lee, W. S. & Hsu, C., 十二月 2006, 於 : Stroke. 37, 12, p. 3025-3031 7 p.

研究成果: 雜誌貢獻文章

Nitric Oxide Synthase Type II
Subarachnoid Hemorrhage
Transcriptional Activation
Estradiol
Gene Expression