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研究成果 2003 2019

  • 1413 引文
  • 16 h-指數
  • 62 文章
  • 5 會議貢獻
  • 1 回顧型文獻
篩選
文章
2019
Multicenter Studies
Odds Ratio
Confidence Intervals
Hospital Mortality
Necrotizing Fasciitis
1 引文 (Scopus)

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., 一月 1 2019, 於 : Biomaterials. 190-191, p. 1-10 10 p.

研究成果: 雜誌貢獻文章

Catenins
Cell Polarity
Stem cells
Mesenchymal Stromal Cells
Shear stress

Diversity of nasal microbiota and its interaction with surface microbiota among residents in healthcare institutes

Chen, C. H., Liou, M. L., Lee, C. Y., Chang, M. C., Kuo, H. Y. & Chang, T. H., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 6175.

研究成果: 雜誌貢獻文章

開啟存取
Microbiota
Nose
Delivery of Health Care
Corynebacterium
Nasal Cavity
1 引文 (Scopus)
開啟存取
Bariatric Surgery
Glomerular Filtration Rate
Chronic Renal Insufficiency
Weight Loss
Propensity Score
3 引文 (Scopus)

Identification of potential biomarkers related to glioma survival by gene expression profile analysis

Hsu, J. B. K., Chang, T. H., Lee, G. A., Lee, T. Y. & Chen, C. Y., 三月 20 2019, 於 : BMC Medical Genomics. 11, 34.

研究成果: 雜誌貢獻文章

開啟存取
Transcriptome
Glioma
Biomarkers
Survival
Genes

Liver X Receptor/Retinoid X Receptor Pathway Plays a Regulatory Role in Pacing-Induced Cardiomyopathy

Lin, Y-S., Chang, T-H., Shi, C-S., Wang, Y-Z., Ho, W-C., Huang, H-D., Chang, S-T., Pan, K-L. & Chen, M-C., 一月 8 2019, 於 : Journal of the American Heart Association. 8, 1, p. e009146

研究成果: 雜誌貢獻文章

Retinoid X Receptors
Cardiomyopathies
Ventricular Septum
Genes
Fibrosis
2018
8 引文 (Scopus)

A three–MicroRNA signature as a potential biomarker for the early detection of oral cancer

Chang, Y. A., Weng, S. L., Yang, S. F., Chou, C. H., Huang, W. C., Tu, S. J., Chang, T. H., Huang, C. N., Jong, Y. J. & Huang, H. D., 三月 7 2018, 於 : International Journal of Molecular Sciences. 19, 3, 758.

研究成果: 雜誌貢獻文章

biomarkers
Mouth Neoplasms
Biomarkers
MicroRNAs
Early Detection of Cancer
5 引文 (Scopus)

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation

Chiang, W. F., Cheng, T. M., Chang, C. C., Pan, S. H., Changou, C. A., Chang, T. H., Lee, K. H., Wu, S. Y., Chen, Y. F., Chuang, K. H., Shieh, D. B., Chen, Y. L., Tu, C. C., Tsui, W. L. & Wu, M. H., 一月 4 2018, 於 : Oncogene. 37, 1, p. 116-127 12 p.

研究成果: 雜誌貢獻文章

Carcinoembryonic Antigen
Cell Adhesion Molecules
Glycosylation
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
2 引文 (Scopus)

Differential Gene Expression Profile of Renin-Angiotensin System in the Left Atrium in Mitral Regurgitation Patients

Liu, W. H., Fang, Y. N., Wu, C. C., Chen, M. C., Chang, J. P., Lin, Y. S., Pan, K. L., Ho, W. C., Chang, T. H., Huang, Y. K., Fang, C. Y., Chen, C. J. & Lee, W. C., 一月 1 2018, 於 : Disease Markers. 2018, 1 p.

研究成果: 雜誌貢獻文章

Angiotensins
Mitral Valve Insufficiency
Renin-Angiotensin System
Heart Atria
Transcriptome

Idi1 and Hmgcs2 are affected by stretch in HL-1 atrial myocytes

Fang, C. Y., Chen, M. C., Chang, T. H., Wu, C. C., Chang, J. P., Huang, H. D., Ho, W. C., Wang, Y. Z., Pan, K. L., Lin, Y. S., Huang, Y. K., Chen, C. J. & Lee, W. C., 一月 1 2018, 於 : International Journal of Molecular Sciences. 19, 12, 4094.

研究成果: 雜誌貢獻文章

muscle cells
genes
Muscle Cells
Genes
Cholesterol
3 引文 (Scopus)

Risk analysis of malignant potential of oral verrucous hyperplasia: A follow-up study of 269 patients and copy number variation analysis

Wu, M. H., Luo, J. D., Wang, W. C., Chang, T. H., Hwang, W. L., Lee, K. H., Liu, S. Y., Yang, J. W., Chiou, C. T., Chang, C. H. & Chiang, W. F., 一月 1 2018, (接受/付印) 於 : Head and Neck.

研究成果: 雜誌貢獻文章

Hyperplasia
Oral Submucous Fibrosis
Mastication
Survival Rate
Gene Amplification
2 引文 (Scopus)

Vaginal microbiome variances in sample groups categorized by clinical criteria of bacterial vaginosis

Chen, H. M., Chang, T. H., Lin, F. M., Liang, C., Chiu, C. M., Yang, T. L., Yang, T., Huang, C. Y., Cheng, Y. N., Chang, Y. A., Chang, P. Y. & Weng, S. L., 十二月 31 2018, 於 : BMC Genomics. 19, 876.

研究成果: 雜誌貢獻文章

Bacterial Vaginosis
Microbiota
Metagenomics
Gardnerella
Prevotella
2017
10 引文 (Scopus)

Activation of TWIST1 by COL11A1 promotes chemoresistance and inhibits apoptosis in ovarian cancer cells by modulating NF-κB-mediated IKKβ expression

Wu, Y. H., Huang, Y. F., Chang, T. H. & Chou, C. Y., 十二月 1 2017, 於 : International Journal of Cancer. 141, 11, p. 2305-2317 13 p.

研究成果: 雜誌貢獻文章

Ovarian Neoplasms
Apoptosis
Messenger RNA
Twist-Related Protein 1
Collagen Type XI
2 引文 (Scopus)

Ankylosing spondylitis and the risk of cancer

Chang, C. C., Chang, C. W., Nguyen, P. A. A., Chang, T. H., Shih, Y. L., Chang, W. Y., Horng, J. T., Lee, O. K. S. & Ho, J. H. C., 2017, 於 : Oncology Letters. 14, 2, p. 1315-1322 8 p.

研究成果: 雜誌貢獻文章

Ankylosing Spondylitis
Neoplasms
Incidence
Confidence Intervals
Bone Neoplasms
2 引文 (Scopus)
Gene Expression Profiling
Benzodiazepines
Gene expression
Bioinformatics
Breast Neoplasms
13 引文 (Scopus)

Diversity and enterotype in gut bacterial community of adults in Taiwan

Liang, C., Tseng, H. C., Chen, H. M., Wang, W. C., Chiu, C. M., Chang, J. Y., Lu, K. Y., Weng, S. L., Chang, T. H., Chang, C. H., Weng, C. T., Wang, H. M. & Huang, H. D., 一月 25 2017, 於 : BMC Genomics. 18, 932.

研究成果: 雜誌貢獻文章

Microbiota
Taiwan
Feeding Behavior
Prevotella
Bacteroides
2 引文 (Scopus)

Genome-wide discovery of viral microRNAs based on phylogenetic analysis and structural evolution of various human papillomavirus subtypes

Weng, S-L., Huang, K-Y., Weng, J. T-Y., Hung, F-Y., Chang, T-H. & Lee, T-Y., 五月 20 2017, 於 : Briefings in Bioinformatics.

研究成果: 雜誌貢獻文章

MicroRNAs
Genes
Genome
RNA
Viruses
5 引文 (Scopus)

Identification of natural antimicrobial peptides from bacteria through metagenomic and metatranscriptomic analysis of high-throughput transcriptome data of Taiwanese oolong teas

Huang, K. Y., Chang, T. H., Jhong, J. H., Chi, Y. H., Li, W. C., Chan, C. L., Robert Lai, K. & Lee, T. Y., 十二月 21 2017, 於 : BMC Systems Biology. 11, 131.

研究成果: 雜誌貢獻文章

Metagenomics
Tea
Transcriptome
Peptides
Bacteria
10 引文 (Scopus)

Investigation and identification of protein carbonylation sites based on position-specific amino acid composition and physicochemical features

Weng, S. L., Huang, K. Y., Kaunang, F. J., Huang, C. H., Kao, H. J., Chang, T. H., Wang, H. Y., Lu, J. J. & Lee, T. Y., 三月 14 2017, 於 : BMC Bioinformatics. 18, 66.

研究成果: 雜誌貢獻文章

Protein Carbonylation
Carbonylation
Amino Acids
Amino acids
Proteins
2016
9 引文 (Scopus)

Circulating miR-148b-3p and miR-409-3p as biomarkers for heart failure in patients with mitral regurgitation

Chen, M. C., Chang, T. H., Chang, J. P., Huang, H. D., Ho, W. C., Lin, Y. S., Pan, K. L., Liu, W. H. & Huang, Y. K., 十一月 1 2016, 於 : International Journal of Cardiology. 222, p. 148-154 7 p.

研究成果: 雜誌貢獻文章

Mitral Valve Insufficiency
Heart Failure
Biomarkers
MicroRNAs
Serum
3 引文 (Scopus)

Deciphering the gene expression profile of peroxisome proliferator-activated receptor signaling pathway in the left atria of patients with mitral regurgitation

Chen, M. C., Chang, J. P., Lin, Y. S., Pan, K. L., Ho, W. C., Liu, W. H., Chang, T. H., Huang, Y. K., Fang, C. Y. & Chen, C. J., 六月 2 2016, 於 : Journal of Translational Medicine. 14, 1, 157.

研究成果: 雜誌貢獻文章

Peroxisome Proliferator-Activated Receptors
Mitral Valve Insufficiency
Heart Atria
Transcriptome
Gene expression
1 引文 (Scopus)

Exploring regulatory mechanisms of atrial myocyte hypertrophy of mitral regurgitation through gene expression profiling analysis: Role of NFAT in cardiac hypertrophy

Chang, T. H., Chen, M. C., Chang, J. P., Huang, H. D., Ho, W. C., Lin, Y. S., Pan, K. L., Huang, Y. K., Liu, W. H. & Wu, C. C., 十二月 1 2016, 於 : PLoS One. 11, 12, 0166791.

研究成果: 雜誌貢獻文章

Cardiomegaly
Mitral Valve Insufficiency
Gene Expression Profiling
hypertrophy
Gene expression
5 引文 (Scopus)

Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions

Lee, M. C., Huang, H. J., Chang, T. H., Huang, H. C., Hsieh, S. Y., Chen, Y. S., Chou, W. Y., Chiang, C. H., Lai, C. H. & Shiau, C. Y., 七月 4 2016, 於 : Scientific Reports. 6, 29311.

研究成果: 雜誌貢獻文章

Chromatin
Epithelial Cells
Binding Sites
Genome
Cell Line
25 引文 (Scopus)

SOHSite: Incorporating evolutionary information and physicochemical properties to identify protein S-sulfenylation sites

Bui, V. M., Weng, S. L., Lu, C. T., Chang, T. H., Weng, J. T. Y. & Lee, T. Y., 一月 11 2016, 於 : BMC Genomics. 17, 1, 9.

研究成果: 雜誌貢獻文章

Protein S
Amino Acids
Position-Specific Scoring Matrices
Biological Phenomena
Amino Acid Substitution
3 引文 (Scopus)

Temporal genetic modifications after controlled cortical impact—understanding traumatic brain injury through a systematic network approach

Wong, Y. H., Wu, C. C., Wu, J. C. C., Lai, H. Y., Chen, K. Y., Jheng, B. R., Chen, M. C., Chang, T. H. & Chen, B. S., 二月 6 2016, 於 : International Journal of Molecular Sciences. 17, 2

研究成果: 雜誌貢獻文章

brain damage
Brain
Biological Phenomena
biomarkers
proteins
2015
4 引文 (Scopus)

Applying NGS data to find evolutionary network biomarkers from the early and late stages of hepatocellular carcinoma

Wong, Y. H., Wu, C. C., Lin, C. L., Chen, T. S., Chang, T. H. & Chen, B. S., 2015, 於 : BioMed Research International. 2015, 391475.

研究成果: 雜誌貢獻文章

Protein Interaction Maps
Biomarkers
Hepatocellular Carcinoma
Liver Neoplasms
Neoplasms
13 引文 (Scopus)

Characterization and identification of ubiquitin conjugation sites with E3 ligase recognition specificities

Nguyen, V. N., Huang, K. Y., Huang, C. H., Chang, T. H., Bretaña, N. A., Lai, K. R., Weng, J. T. Y. & Lee, T. Y., 一月 21 2015, 於 : BMC Bioinformatics. 16, 1, S1.

研究成果: 雜誌貢獻文章

Ubiquitin-Protein Ligases
Conjugation
Ubiquitin
Specificity
Substrate
30 引文 (Scopus)

COL11A1 confers chemoresistance on ovarian cancer cells through the activation of Akt/c/EBPß pathway and PDK1 stabilization

Wu, Y. H., Chang, T. H., Huang, Y. F., Chen, C. C. & Chou, C. Y., 2015, 於 : Oncotarget. 6, 27, p. 23748-23763 16 p.

研究成果: 雜誌貢獻文章

Ovarian Neoplasms
Ubiquitination
Collagen Type XI
Carcinoma
Microarray Analysis
3 引文 (Scopus)

Enhanced expression of ROCK in left atrial myocytes of mitral regurgitation: A potential mechanism of myolysis

Chen, H. C., Chang, J. P., Chang, T. H., Lin, Y. S., Huang, Y. K., Pan, K. L., Fang, C. Y., Chen, C. J., Ho, W. C. & Chen, M. C., 五月 9 2015, 於 : BMC Cardiovascular Disorders. 15, 1, 33.

研究成果: 雜誌貢獻文章

rho-Associated Kinases
Mitral Valve Insufficiency
Muscle Cells
Atrial Fibrillation
Fluorescent Antibody Technique
Mesenchymal Stromal Cells
Actin Cytoskeleton
Stem Cells
8 引文 (Scopus)

Identification of network-based biomarkers of cardioembolic stroke using a systems biology approach with time series data

Wong, Y. H., Wu, C. C., Lai, H. Y., Jheng, B. R., Weng, H. Y., Chang, T. H. & Chen, B. S., 十二月 9 2015, 於 : BMC Systems Biology. 9, 6, S4.

研究成果: 雜誌貢獻文章

Systems Biology
Biomarkers
Time Series Data
Stroke
Time series
27 引文 (Scopus)

Oscillatory shear stress mediates directional reorganization of actin cytoskeleton and alters differentiation propensity of mesenchymal stem cells

Kuo, Y. C., Chang, T. H., Hsu, W. T., Zhou, J., Lee, H. H., Hui-Chun Ho, J., Chien, S. & Kuang-Sheng, O., 二月 1 2015, 於 : Stem Cells. 33, 2, p. 429-442 14 p.

研究成果: 雜誌貢獻文章

Catenins
Mesenchymal Stromal Cells
Actin Cytoskeleton
Actins
Wnt Signaling Pathway
8 引文 (Scopus)

Solanum incanum extract downregulates aldehyde dehydrogenase 1-mediated stemness and inhibits tumor formation in ovarian cancer cells

Wu, Y. H., Chiu, W. T., Young, M. J., Chang, T. H., Huang, Y. F. & Chou, C. Y., 2015, 於 : Journal of Cancer. 6, 10, p. 1011-1019 9 p.

研究成果: 雜誌貢獻文章

Solanum
Ovarian Neoplasms
Down-Regulation
Neoplasms
Inhibitory Concentration 50
9 引文 (Scopus)

Unraveling regulatory mechanisms of atrial remodeling of mitral regurgitation pigs by gene expression profiling analysis: Role of type i angiotensin II receptor antagonist

Chen, M. C., Chang, J. P., Chang, T. H., Hsu, S. D., Huang, H. D., Ho, W. C., Wang, F. S., Hsiao, C. C. & Liu, W. H., 五月 1 2015, 於 : Translational Research. 165, 5, p. 599-620 22 p.

研究成果: 雜誌貢獻文章

Atrial Remodeling
Angiotensin Receptor Antagonists
Mitral Valve Insufficiency
Gene Expression Profiling
Gene expression
10 引文 (Scopus)

ViralmiR: A support-vector-machine-based method for predicting viral microRNA precursors

Huang, K. Y., Lee, T. Y., Teng, Y. C. & Chang, T. H., 一月 21 2015, 於 : BMC Bioinformatics. 16, 1, S9.

研究成果: 雜誌貢獻文章

MicroRNA
MicroRNAs
Viruses
Precursor
Support vector machines
2014
46 引文 (Scopus)

Allopurinol therapy in gout patients does not associate with beneficial cardiovascular outcomes: A population-based matched-cohort study

Kok, V. C., Horng, J. T., Chang, W. S., Hong, Y. F. & Chang, T. H., 六月 4 2014, 於 : PLoS One. 9, 6, e99102.

研究成果: 雜誌貢獻文章

allopurinol
gout
Allopurinol
Gout
cohort studies
2 引文 (Scopus)
Cloud computing
Gene expression
Technology
Gene Expression
Microarrays
52 引文 (Scopus)

Bacterial communities in semen from men of infertile couples: Metagenomic sequencing reveals relationships of seminal microbiota to semen quality

Weng, S. L., Chiu, C. M., Lin, F. M., Huang, W. C., Liang, C., Yang, T., Yang, T. L., Liu, C. Y., Wu, W. Y., Chang, Y. A., Chang, T. H. & Huang, H. D., 十月 23 2014, 於 : PLoS One. 9, 10, e110152.

研究成果: 雜誌貢獻文章

Metagenomics
Semen Analysis
Prevotella
Microbiota
Lactobacillus
6 引文 (Scopus)

Clinical detection of human probiotics and human pathogenic bacteria by using a novel high-throughput platform based on next generation sequencing

Chiu, C. M., Lin, F. M., Chang, T. H., Huang, W. C., Liang, C., Yang, T., Wu, W. Y., Yang, T. L., Weng, S. L. & Huang, H. D., 一月 13 2014, 於 : Journal of Clinical Bioinformatics. 4, 1, 1.

研究成果: 雜誌貢獻文章

Probiotics
Bacteria
Microbiota
Vagina
Microbiology
68 引文 (Scopus)

COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer

Wu, Y. H., Chang, T. H., Huang, Y. F., Huang, H. D. & Chou, C. Y., 七月 11 2014, 於 : British Dental Journal. 217, 1, p. 3432-3440 9 p.

研究成果: 雜誌貢獻文章

Ovarian Neoplasms
Transforming Growth Factors
Neoplasms
Disease Progression
Collagen Type XI
Hydroxymethylglutaryl-CoA Reductase Inhibitors
19 引文 (Scopus)

Effects of statins on incident dementia in patients with type 2 DM: A population-based retrospective cohort study in Taiwan

Chen, J. M., Chang, C. W., Chang, T. H., Hsu, C. C., Horng, J. T. & Sheu, W. H. H., 二月 10 2014, 於 : PLoS One. 9, 2, e88434.

研究成果: 雜誌貢獻文章

Hydroxymethylglutaryl-CoA Reductase Inhibitors
dementia
cohort studies
Taiwan
Dementia
14 引文 (Scopus)

Identification and characterization of lysine-methylated sites on histones and non-histone proteins

Lee, T. Y., Chang, C. W., Lu, C. T., Cheng, T. H. & Chang, T. H., 2014, 於 : Computational Biology and Chemistry. 50, p. 11-18 8 p.

研究成果: 雜誌貢獻文章

Histones
Lysine
Proteins
Protein
Methylation
504 引文 (Scopus)

MiRTarBase update 2014: An information resource for experimentally validated miRNA-target interactions

Hsu, S. D., Tseng, Y. T., Shrestha, S., Lin, Y. L., Khaleel, A., Chou, C. H., Chu, C. F., Huang, H. Y., Lin, C. M., Ho, S. Y., Jian, T. Y., Lin, F. M., Chang, T. H., Weng, S. L., Liao, K. W., Liao, I. E., Liu, C. C. & Huang, H. D., 一月 1 2014, 於 : Nucleic Acids Research. 42, D1

研究成果: 雜誌貢獻文章

MicroRNAs
Databases
Small Untranslated RNA
Systems Biology
Information Storage and Retrieval
2 引文 (Scopus)

Novel bioinformatics approaches for analysis of high-throughput biological data

Weng, J. T. Y., Wu, L. C., Chang, W. C., Chang, T. H., Akutsu, T. & Lee, T. Y., 十二月 28 2014, 於 : BioMed Research International. 2014, 814092.

研究成果: 雜誌貢獻文章

40 引文 (Scopus)

Systematic analysis of the association between gut flora and obesity through high-throughput sequencing and bioinformatics approaches

Chiu, C. M., Huang, W. C., Weng, S. L., Tseng, H. C., Liang, C., Wang, W. C., Yang, T., Yang, T. L., Weng, C. T., Chang, T. H. & Huang, H. D., 2014, 於 : BioMed Research International. 2014, 906168.

研究成果: 雜誌貢獻文章

Bioinformatics
Computational Biology
Bacteria
Obesity
Throughput
10 引文 (Scopus)

The ability to suppress macrophage-mediated inflammation in orbital fat stem cells is controlled by miR-671-5p

Lien, G. S., Liu, J-F., Chien, M. H., Hsu, W. T., Chang, T. H., Ku, C. C., Ji, A. T. Q., Tan, P., Hsieh, T. L., Lee, L. M. & Ho, J. H., 八月 13 2014, 於 : Stem Cell Research and Therapy. 5, 4, 97.

研究成果: 雜誌貢獻文章

Macrophages
Stem cells
Adipocytes
Stem Cells
Fats
16 引文 (Scopus)

The effects of actin cytoskeleton perturbation on keratin intermediate filament formation in mesenchymal stem/stromal cells

Chang, T. H., Huang, H. D., Ong, W. K., Fu, Y. J., Lee, O. K., Chien, S. & Ho, J. H., 四月 2014, 於 : Biomaterials. 35, 13, p. 3934-3944 11 p.

研究成果: 雜誌貢獻文章

Keratin
Intermediate Filaments
Keratins
Stem cells
Mesenchymal Stromal Cells
2013
28 引文 (Scopus)

A computational approach for identifying microRNA-target interactions using highthroughput CLIP and PAR-CLIP sequencing

Chou, C. H., Lin, F. M., Chou, M. T., Hsu, S. H. D., Chang, T. H., Weng, S. L., Shrestha, S., Hsiao, C. C., Hung, J. H. & Huang, H. D., 一月 21 2013, 於 : BMC Genomics. 14, S2.

研究成果: 雜誌貢獻文章

Ribonucleosides
MicroRNAs
Immunoprecipitation
Argonaute Proteins
Web Browser
144 引文 (Scopus)

An enhanced computational platform for investigating the roles of regulatory RNA and for identifying functional RNA motifs

Chang, T. H., Huang, H. Y., Hsu, J. B. K., Weng, S. L., Horng, J. T. & Huang, H. D., 一月 21 2013, 於 : BMC Bioinformatics. 14, S4.

研究成果: 雜誌貢獻文章

Nucleotide Motifs
RNA
Information Storage and Retrieval
Riboswitch
AU Rich Elements