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研究成果

  • 2576 引文
  • 26 h-指數
  • 77 文章
  • 1 快報
篩選
文章
2020

Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models

Liu, Y. C., Wang, H. L., Huang, Y. Z., Weng, Y. H., Chen, R. S., Tsai, W. C., Yeh, T. H., Lu, C. S., Chen, Y. L., Lin, Y. W., Chen, Y. J., Hsu, C. C., Chiu, C. H. & Chiu, C. C., 五月 2020, 於 : Biochemical Pharmacology. 175, 113919.

研究成果: 雜誌貢獻文章

2019

Association of Antiviral Therapy with Risk of Parkinson Disease in Patients with Chronic Hepatitis C Virus Infection

Lin, W. Y., Lin, M. S., Weng, Y. H., Yeh, T. H., Lin, Y. S., Fong, P. Y., Wu, Y. R., Lu, C. S., Chen, R. S. & Huang, Y. Z., 九月 2019, 於 : JAMA Neurology. 76, 9, p. 1019-1027 9 p.

研究成果: 雜誌貢獻文章

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8 引文 斯高帕斯(Scopus)

Combined assessment of serum alpha-synuclein and RAB35 is a better biomarker for Parkinson’s disease

Wang, H. L., Lu, C. S., Yeh, T. H., Shen, Y. M., Weng, Y. H., Huang, Y. Z., Chen, R. S., Liu, Y. C., Cheng, Y. C., Chang, H. C., Chen, Y. L., Chen, Y. J., Lin, Y. W., Hsu, C. C., Lin, H. L., Chiu, C. H. & Chiu, C. C., 十月 2019, 於 : Journal of Clinical Neurology (Korea). 15, 4, p. 488-495 8 p.

研究成果: 雜誌貢獻文章

Generation of induced pluripotent stem cells from a young-onset Parkinson's disease patient carrying the compound heterozygous PLA2G6 p.D331Y/p.M358IfsX mutations

Chiu, C. C., Wang, H. L., Weng, Y. H., Chen, R. S., Chen, C. M., Yeh, T. H., Lu, C. S., Chen, Y. J., Liu, Y. C., Huang, Y. Z. & Chang, K. H., 十月 2019, 於 : Stem Cell Research. 40, 101552.

研究成果: 雜誌貢獻文章

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Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade

Chiu, C. C., Yeh, T. H., Chen, R. S., Chen, H. C., Huang, Y. Z., Weng, Y. H., Cheng, Y. C., Liu, Y. C., Cheng, A. J., Lu, Y. C., Chen, Y. J., Lin, Y. W., Hsu, C. C., Chen, Y. L., Lu, C. S. & Wang, H. L., 九月 13 2019, 於 : Frontiers in Cellular Neuroscience. 13, 399.

研究成果: 雜誌貢獻文章

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3 引文 斯高帕斯(Scopus)
2018

A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., 二月 1 2018, 於 : Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

研究成果: 雜誌貢獻文章

C9orf72 is essential for neurodevelopment and motility mediated by Cyclin G1

Yeh, T. H., Liu, H. F., Li, Y. W., Lu, C. S., Shih, H. Y., Chiu, C. C., Lin, S. J., Huang, Y. C. & Cheng, Y. C., 六月 1 2018, 於 : Experimental Neurology. 304, p. 114-124 11 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Genetic diagnosis of neurofibromatosis type 1: Targeted next- generation sequencing with Multiple Ligation-Dependent Probe Amplification analysis

Wu-Chou, Y. H., Hung, T. C., Lin, Y. T., Cheng, H. W., Lin, J. L., Lin, C. H., Yu, C. C., Chen, K. T., Yeh, T. H. & Chen, Y. R., 十月 5 2018, 於 : Journal of Biomedical Science. 25, 1, 72.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

International Parkinsonism Genetics Network, 七月 1 2018, 於 : The Lancet Neurology. 17, 7, p. 597-608 12 p.

研究成果: 雜誌貢獻文章

31 引文 斯高帕斯(Scopus)

PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model

Chiu, C. C., Lu, C. S., Weng, Y. H., Chen, Y. L., Huang, Y. Z., Chen, R. S., Cheng, Y. C., Huang, Y. C., Liu, Y. C., Lai, S. C., Lin, K. J., Lin, Y. W., Chen, Y. J., Chen, C. L., Yeh, T. H. & Wang, H. L., 一月 1 2018, (接受/付印) 於 : Molecular Neurobiology.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Pparα deficiency inhibits the proliferation of neuronal and glial precursors in the zebrafish central nervous system

Hsieh, Y. C., Chiang, M. C., Huang, Y. C., Yeh, T. H., Shih, H. Y., Liu, H. F., Chen, H. Y., Wang, C. P. & Cheng, Y. C., 十二月 1 2018, 於 : Developmental Dynamics. 247, 12, p. 1264-1275 12 p.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)
4 引文 斯高帕斯(Scopus)
2017

Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation

Huang, Y. C., Lin, S. J., Shih, H. Y., Chou, C. H., Chu, H. H., Chiu, C. C., Yuh, C. H., Yeh, T. H. & Cheng, Y. C., 2017, 於 : Oncotarget. 8, 38, p. 63110-63120 11 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
7 引文 斯高帕斯(Scopus)

Medical treatment guidelines for acute migraine attacks

Treatment Guideline Subcommittee of Taiwan Headache Society, 一月 1 2017, 於 : Acta Neurologica Taiwanica. 26, 2, p. 78-96 19 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Medical treatment guidelines for preventive treatment of migraine

Huang, T. C., Lai, T. H., Wang, S. J., Wang, P. J., Wang, Y. F., Lee, L. H., Lin, K. C., Wu, Z. A., Shih, C. S., Hsu, Y. C., Chen, Y. Y., Chen, W. H., Chen, W. T., Chen, P. K., Huang, T. C., Fu, J. L., Yang, C. P., Yeh, T. H., Liao, Y. C., Lai, T. H. 及其他3, Tsai, J. J., Lu, S. R. & Treatment Guideline Subcommittee of Taiwan Headache Society, 一月 1 2017, 於 : Acta Neurologica Taiwanica. 26, 1, p. 33-35 3 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

PARK14 PLA2G6 mutants are defective in preventing rotenoneinduced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway

Chiu, C. C., Yeh, T. H., Lu, C. S., Huang, Y. C., Cheng, Y. C., Huang, Y. Z., Weng, Y. H., Liu, Y. C., Lai, S. C., Chen, Y. L., Chen, Y. J., Chen, C. L., Chen, H. Y., Lin, Y. W. & Wang, H. L., 2017, 於 : Oncotarget. 8, 45, p. 79046-79060 15 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

Primary Central Nervous System Lymphomas of the Brain: A Retrospective Analysis in a Single Institution

Lin, T. K., Yeh, T. H., Hsu, P. W., Chuang, C. C., Tu, P. H., Chen, P. Y., Jung, S. M., Wei, K. C. & Huang, Y. C., 七月 1 2017, 於 : World Neurosurgery. 103, p. 550-556 7 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Regulator of G protein signaling 2 (Rgs2) regulates neural crest development through Pparδ-Sox10 cascade

Lin, S. J., Chiang, M. C., Shih, H. Y., Hsu, L. S., Yeh, T-H., Huang, Y. C., Lin, C-Y. & Cheng, Y. C., 三月 2017, 於 : Biochimica et Biophysica Acta - General Subjects. 1864, 3, p. 463-474 12 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Sleep disturbances in Taiwanese patients with Parkinson's disease

Lin, Y. Y., Chen, R. S., Lu, C. S., Huang, Y. Z., Weng, Y. H., Yeh, T. H., Lin, W. Y. & Hung, J., 十月 1 2017, 於 : Brain and Behavior. 7, 10, e00806.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2016

(R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model

Weng, Y. H., Chen, C. Y., Lin, K. J., Chen, Y. L., Yeh, T. H., Hsiao, I. T., Chen, I. J., Lu, C. S. & Wang, H. L., 一月 1 2016, 於 : Experimental Neurology. 275, p. 104-115 12 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

Diversified psychiatric presentation in a case of progressive supranuclear palsy

Chiu, Y. W., Lee, S. H. & Yeh, T. H., 十二月 1 2016, 於 : Journal of Clinical Gerontology and Geriatrics. 7, 4, p. 164-167 4 p.

研究成果: 雜誌貢獻文章

Effects of intravenous and oral magnesium on reducing migraine: A meta-analysis of randomized controlled trials

Chiu, H-Y., Yeh, T. H., Huang, Y. C. & Chen, P. Y., 2016, 於 : Pain Physician. 19, 1, p. E97-E112

研究成果: 雜誌貢獻文章

27 引文 斯高帕斯(Scopus)

Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson's disease

Chiu, C. C., Yeh, T. H., Lai, S. C., Weng, Y. H., Huang, Y. C., Cheng, Y. C., Chen, R. S., Huang, Y. Z., Hung, J., Chen, C. C., Lin, W. Y., Chang, H. C., Chen, Y. J., Chen, C. L., Chen, H. Y., Lin, Y. W., Wu-Chou, Y. H., Wang, H. L. & Lu, C. S., 2016, 於 : Oncotarget. 7, 34, p. 54215-54227 13 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

Paroxysmal exercise-induced dystonia within the phenotypic spectrum of ECHS1 deficiency

Olgiati, S., Skorvanek, M., Quadri, M., Minneboo, M., Graafland, J., Breedveld, G. J., Bonte, R., Ozgur, Z., van den Hout, M. C. G. N., Schoonderwoerd, K., Verheijen, F. W., van IJcken, W. F. J., Chien, H. F., Barbosa, E. R., Chang, H. C., Lai, S. C., Yeh, T. H., Lu, C. S., Wu-Chou, Y. H., Kievit, A. J. A. 及其他7, Han, V., Gdovinova, Z., Jech, R., Hofstra, R. M. W., Ruijter, G. J. G., Mandemakers, W. & Bonifati, V., 七月 1 2016, 於 : Movement Disorders. 31, 7, p. 1041-1048 8 p.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)
2015

Clinical and genetic analysis of Taiwanese patients with hereditary spastic paraplegia type 5

Lan, M. Y., Yeh, T., Chang, Y. Y., Kuo, H. C., Sun, H. S., Lai, S. C. & Lu, C. S., 一月 1 2015, 於 : European Journal of Neurology. 22, 1, p. 211-214 4 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Deltex1 is inhibited by the Notch-Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation

Cheng, Y. C., Huang, Y. C., Yeh, T. H., Shih, H. Y., Lin, C. Y., Lin, S. J., Chiu, C. C., Huang, W. C. & Jiang, Y. J., 十二月 30 2015, 於 : Neural Development. 10, 1, 28.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism

Chiu, C. C., Yeh, T. H., Lai, S. C., Wu-Chou, Y. H., Chen, C. H., Mochly-Rosen, D., Huang, Y. C., Chen, Y. J., Chen, C. L., Chang, Y. M., Wang, H. L. & Lu, C. S., 一月 1 2015, 於 : Experimental Neurology. 263, p. 244-253 10 p.

研究成果: 雜誌貢獻文章

44 引文 斯高帕斯(Scopus)

T1-11 and JMF1907 ameliorate polyglutamine-expanded ataxin-3-induced neurodegeneration, transcriptional dysregulation and ataxic symptom in the SCA3 transgenic mouse

Chou, A. H., Chen, Y. L., Chiu, C. C., Yuan, S. J., Weng, Y. H., Yeh, T. H., Lin, Y. L., Fang, J. M. & Wang, H. L., 八月 22 2015, 於 : Neuropharmacology. 99, p. 308-317 10 p.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)

The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiation

Huang, Y. C., Shih, H. Y., Lin, S. J., Chiu, C. C., Ma, T. L., Yeh, T. H. & Cheng, Y. C., 五月 1 2015, 於 : Developmental Neurobiology. 75, 5, p. 452-462 11 p.

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)

The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis

Cheng, Y. C., Chiang, M. C., Shih, H. Y., Ma, T. L., Yeh, T. H., Huang, Y. C., Lin, C. Y. & Lin, S. J., 一月 1 2015, 於 : Developmental Biology. 397, 1, p. 116-128 13 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
2014

(G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse

Chou, J. S., Chen, C. Y., Chen, Y. L., Weng, Y. H., Yeh, T. H., Lu, C. S., Chang, Y. M. & Wang, H. L., 2014, 於 : Neurobiology of Disease. 68, p. 190-199 10 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)

A novel XK gene mutation in a Taiwanese family with McLeod syndrome

Chen, P. Y., Lai, S. C., Yang, C. C., Lee, M. J., Chiu, Y. H., Yan, S. H., Lu, C. S. & Yeh, T. H., 五月 15 2014, 於 : Journal of the Neurological Sciences. 340, 1-2, p. 221-224 4 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

High frequency of SPG4 in Taiwanese families with autosomal dominant hereditary spastic paraplegia

Lan, M. Y., Chang, Y. Y., Yeh, T. H., Lai, S. C., Liou, C. W., Kuo, H. C., Wu, Y. R., Lyu, R. K., Hung, J. W., Chang, Y. C. & Lu, C. S., 十一月 25 2014, 於 : BMC Neurology. 14, 1, 216.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

Transglutaminase 2 expression is increased as a function of malignancy grade and negatively regulates cell growth in meningioma

Huang, Y. C., Wei, K. C., Chang, C. N., Chen, P. Y., Hsu, P. W., Chen, C. P., Lu, C. S., Wang, H. L., Gutmann, D. H. & Yeh, T. H., 九月 23 2014, 於 : PLoS One. 9, 9, e108228.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)
2013

Dystonic opisthotonus: A "red flag" for neurodegeneration with brain iron accumulation syndromes?

Stamelou, M., Lai, S. C., Aggarwal, A., Schneider, S. A., Houlden, H., Yeh, T. H., Batla, A., Lu, C. S., Bhatt, M. & Bhatia, K. P., 九月 2013, 於 : Movement Disorders. 28, 10, p. 1325-1329 5 p.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)

Genetic variants of SNCA and LRRK2 genes are associated with sporadic PD susceptibility: A replication study in a Taiwanese cohort

Wu-Chou, Y. H., Chen, Y. T., Yeh, T. H., Chang, H. C., Weng, Y. H., Lai, S. C., Huang, C. L., Chen, R. S., Huang, Y. Z., Chen, C. C., Hung, J., Chuang, W. L., Lin, W. Y., Chen, C. H. & Lu, C. S., 二月 2013, 於 : Parkinsonism and Related Disorders. 19, 2, p. 251-255 5 p.

研究成果: 雜誌貢獻文章

30 引文 斯高帕斯(Scopus)
23 引文 斯高帕斯(Scopus)

Phenotypes and genotypes of patients with pantothenate kinase-associated neurodegeneration in Asian and caucasian populations: 2 cases and literature review

Lee, C. H., Lu, C. S., Chuang, W. L., Yeh, T. H., Jung, S. M., Huang, C. L. & Lai, S. C., 2013, 於 : The Scientific World Journal. 2013, 860539.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)

Screening for C9orf72 repeat expansions in parkinsonian syndromes

Yeh, T. H., Lai, S. C., Weng, Y. H., Kuo, H. C., Wu-Chou, Y. H., Huang, C. L., Chen, R. S., Chang, H. C., Traynor, B. & Lu, C. S., 四月 2013, 於 : Neurobiology of Aging. 34, 4

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)
10 引文 斯高帕斯(Scopus)
2012

(G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD

Chen, C. Y., Weng, Y. H., Chien, K. Y., Lin, J. K., Yeh, T. H., Cheng, Y. P., Lu, C. S. & Wang, H. L., 十月 2012, 於 : Cell Death and Differentiation. 19, 10, p. 1623-1633 11 p.

研究成果: 雜誌貢獻文章

90 引文 斯高帕斯(Scopus)

Familial paroxysmal nonkinesigenic dyskinesia: Clinical and genetic analysis of a Taiwanese family

Yeh, T. H., Lin, J. J., Lai, S. C., Wu-Chou, Y. H., Chen, A. C., Yueh, K. C., Chen, R. S. & Lu, C. S., 十二月 15 2012, 於 : Journal of the Neurological Sciences. 323, 1-2, p. 80-84 5 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: A cross-sectional study

Majounie, E., Renton, A. E., Mok, K., Dopper, E. G. P., Waite, A., Rollinson, S., Chiò, A., Restagno, G., Nicolaou, N., Simon-Sanchez, J., Van Swieten, J. C., Abramzon, Y., Johnson, J. O., Sendtner, M., Pamphlett, R., Orrell, R. W., Mead, S., Sidle, K. C., Houlden, H., Rohrer, J. D. 及其他39, Morrison, K. E., Pall, H., Talbot, K., Ansorge, O., Hernandez, D. G., Arepalli, S., Sabatelli, M., Mora, G., Corbo, M., Giannini, F., Calvo, A., Englund, E., Borghero, G., Floris, G. L., Remes, A. M., Laaksovirta, H., McCluskey, L., Trojanowski, J. Q., Van Deerlin, V. M., Schellenberg, G. D., Nalls, M. A., Drory, V. E., Lu, C. S., Yeh, T. H., Ishiura, H., Takahashi, Y., Tsuji, S., Le Ber, I., Brice, A., Drepper, C., Leader-Williams, N., Kirby, J., Shaw, P., Hardy, J., Tienari, P. J., Heutink, P., Morris, H. R., Pickering-Brown, S. & Traynor, B. J., 四月 2012, 於 : The Lancet Neurology. 11, 4, p. 323-330 8 p.

研究成果: 雜誌貢獻文章

652 引文 斯高帕斯(Scopus)

PLA2G6 mutations in PARK14-linked young-onset parkinsonism and sporadic Parkinson's disease

Lu, C. S., Lai, S. C., Wu, R. M., Weng, Y. H., Huang, C. L., Chen, R. S., Chang, H. C., Wu-Chou, Y. H. & Yeh, T. H., 三月 2012, 於 : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 159 B, 2, p. 183-191 9 p.

研究成果: 雜誌貢獻文章

45 引文 斯高帕斯(Scopus)
2011

Contribution of glucocerebrosidase mutation in a large cohort of sporadic Parkinson's disease in Taiwan

Huang, C. L., Wu-Chou, Y. H., Lai, S. C., Chang, H. C., Yeh, T. H., Weng, Y. H., Chen, R. S., Huang, Y. Z. & Lu, C. S., 十月 2011, 於 : European Journal of Neurology. 18, 10, p. 1227-1232 6 p.

研究成果: 雜誌貢獻文章

30 引文 斯高帕斯(Scopus)

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

Chou, A. H., Chen, S. Y., Yeh, T. H., Weng, Y. H. & Wang, H. L., 二月 2011, 於 : Neurobiology of Disease. 41, 2, p. 481-488 8 p.

研究成果: 雜誌貢獻文章

70 引文 斯高帕斯(Scopus)

PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons

Wang, H. L., Chou, A. H., Wu, A. S., Chen, S. Y., Weng, Y. H., Kao, Y. C., Yeh, T. H., Chu, P. J. & Lu, C. S., 六月 2011, 於 : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1812, 6, p. 674-684 11 p.

研究成果: 雜誌貢獻文章

74 引文 斯高帕斯(Scopus)
2010

High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia

Wu-Chou, Y. H., Yeh, T. H., Wang, C. Y., Lin, J. J., Huang, C. C., Chang, H. C., Lai, S. C., Chen, R. S., Weng, Y. H., Huang, C. L. & Lu, C. S., 六月 2010, 於 : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 4, p. 903-908 6 p.

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)