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研究成果 2010 2019

  • 384 引文
  • 10 h-指數
  • 27 文章
2019
2 引文 (Scopus)
開啟存取
CCAAT-Enhancer-Binding Protein-delta
Platelet-Derived Growth Factor
Glioma
Stem Cells
Interleukin-1
3 引文 (Scopus)
temozolomide
Dehydroepiandrosterone
Glioblastoma
Acetylation
Phosphorylation
Embryonal Carcinoma Stem Cells
Neural Stem Cells
Zinc Fingers
Transcription
Zinc

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J. J., 一月 1 2019, 於 : Molecular Neurobiology.

研究成果: 雜誌貢獻文章

Astrocytes
Synapses
Hippocampus
Neurons
Toll-Like Receptor 2
2018
1 引文 (Scopus)

Ephexin1 is required for Eph-Mediated limb trajectory of spinal motor axons

Chang, C. J., Chang, M. Y., Chou, S. Y., Huang, C. C., Chuang, J. Y., Hsu, T. I., Chang, H. F., Wu, Y. H., Wu, C. C., Morales, D., Kania, A. & Kao, T. J., 二月 21 2018, 於 : Journal of Neuroscience. 38, 8, p. 2043-2056 14 p.

研究成果: 雜誌貢獻文章

Axons
Extremities
Ephrins
Growth Cones
Motor Neurons
6 引文 (Scopus)
Ubiquitination
Glioma
Glioblastoma
Stem Cells
temozolomide

Nck2 is essential for limb trajectory selection by spinal motor axons

Chang, C. J., Chang, M. Y., Lee, Y. C., Chen, K. Y., Hsu, T. I., Wu, Y. H., Chuang, J. Y. & Kao, T. J., 九月 1 2018, 於 : Developmental Dynamics. 247, 9, p. 1043-1056 14 p.

研究成果: 雜誌貢獻文章

Axons
Extremities
Motor Neurons
Ephrins
Neurites
4 引文 (Scopus)
Glioblastoma
Amyloid
Integrins
Serum
Glioma
1 引文 (Scopus)

Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress

Wu, C. C., Lee, P. T., Kao, T. J., Chou, S. Y., Su, R. Y., Lee, Y. C., Yeh, S. H., Liou, J. P., Hsu, T. I., Su, T. P., Chuang, C. K., Chang, W. C. & Chuang, J. Y., 十月 1 2018, 於 : Redox Biology. 19, p. 74-80 7 p.

研究成果: 雜誌貢獻文章

Acetylation
Oxidative stress
Zinc Fingers
Zinc
Oxidative Stress
7 引文 (Scopus)

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

Wang, Y. C., Wu, Y. S., Hung, C. Y., Wang, S. A., Young, M. J., Hsu, T. I. & Hung, J. J., 十二月 1 2018, 於 : Nature Communications. 9, 1, 3996.

研究成果: 雜誌貢獻文章

開啟存取
Tumor Microenvironment
Macrophages
Tumors
Interleukin-6
tumors
2017
9 引文 (Scopus)

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase

Chang, K. Y., Hsu, T. I., Hsu, C. C., Tsai, S. Y., Liu, J. J., Chou, S. W., Liu, M. S., Liou, J. P., Ko, C. Y., Chen, K. Y., Hung, J. J., Chang, W. C., Chuang, C. K., Kao, T. J. & Chuang, J. Y., 十月 1 2017, 於 : Redox Biology. 13, p. 655-664 10 p.

研究成果: 雜誌貢獻文章

temozolomide
Methyltransferases
Glioblastoma
DNA
Proteins
3 引文 (Scopus)

Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma

Chang, K. Y., Huang, C. T., Hsu, T. I., Hsu, C. C., Liu, J. J., Chuang, C. K., Hung, J. J., Chang, W. C., Tsai, K. K. & Chuang, J. Y., 十一月 4 2017, 於 : Biochemical and Biophysical Research Communications. 493, 1, p. 14-19 6 p.

研究成果: 雜誌貢獻文章

Neoplasm Genes
Glioblastoma
Gene expression
Chemical activation
temozolomide
temozolomide
Dehydroepiandrosterone
Glioma
Cytochrome P-450 Enzyme System
Up-Regulation
2016
10 引文 (Scopus)

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

Hsu, T. I., Wang, Y. C., Hung, C. Y., Yu, C. H., Su, W. C., Chang, W. C. & Hung, J. J., 四月 12 2016, 於 : Oncotarget. 7, 15, p. 20840-20854 15 p.

研究成果: 雜誌貢獻文章

Interleukin-10
Lung Neoplasms
Neoplasms
Carcinogenesis
Lung
8 引文 (Scopus)

Suberoylanilide hydroxamic acid represses glioma stem-like cells

Hsu, C. C., Chang, W-C., Hsu, T-I., Liu, J. J., Yeh, S. H., Wang, J-Y., Liou, J-P., Ko, C-Y., Chang, K. Y. & Chuang, J-Y., 十一月 18 2016, 於 : Journal of Biomedical Science. 23, 1, p. 1-12 12 p.

研究成果: 雜誌貢獻文章

Glioma
Stem Cells
Glioblastoma
Cells
Histone Deacetylases
5 引文 (Scopus)

Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy

Wang, Y. C., Wang, S. A., Chen, P. H., Hsu, T. I., Yang, W. B., Chuang, Y. P., Su, W. C., Liaw, H. J., Chang, W. C. & Hung, J. J., 七月 14 2016, 於 : Oncogene. 35, 28, p. 3669-3680 12 p.

研究成果: 雜誌貢獻文章

Ubiquitin
Lung Neoplasms
Peptide Hydrolases
Neoplasms
Single Nucleotide Polymorphism
2015
13 引文 (Scopus)

A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy

Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., 2015, 於 : Oncotarget. 6, 15, p. 13671-13687 17 p.

研究成果: 雜誌貢獻文章

Lung Neoplasms
Endoplasmic Reticulum Stress
Cyclin A2
Growth
Neoplasm Metastasis
21 引文 (Scopus)

MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy

Hsu, T. I., Lin, S. C., Lu, P. S., Chang, W-C., Hung, C. Y., Yeh, Y. M., Su, W. C., Liao, P. C. & Hung, J. J., 二月 12 2015, 於 : Oncogene. 34, 7, p. 826-837 12 p.

研究成果: 雜誌貢獻文章

Neoplasms
Lung Neoplasms
RNA Stability
nucleolin
Matrix Metalloproteinase 7
2014
49 引文 (Scopus)

MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

Hsu, T. I., Hsu, C. H., Lee, K. H., Lin, J. T., Chen, C. S., Chang, K. C., Su, C. Y. J., Hsiao, M. & Lu, P. J., 一月 1 2014, 於 : Oncogenesis. 3, 4, e99.

研究成果: 雜誌貢獻文章

Protein-Serine-Threonine Kinases
MicroRNAs
Prostatic Neoplasms
Carcinogenesis
Neoplasms
13 引文 (Scopus)

Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis

Hung, C. Y., Yang, W. B., Wang, S. A., Hsu, T. I., Chang, W. C. & Hung, J. J., 八月 27 2014, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 12, p. 2843-2854 12 p.

研究成果: 雜誌貢獻文章

Protein Biosynthesis
Carcinogenesis
Proteins
5' Untranslated Regions
Growth Factor Receptors
17 引文 (Scopus)
Proteolysis
Lung Neoplasms
Carcinogenesis
Phosphorylation
Acetylation
49 引文 (Scopus)

Sp1-mediated microRNA-182 expression regulates lung cancer progression

Yang, W. B., Chen, P. H., Hsu, T. I., Fu, T. F., Su, W. C., Liaw, H., Chang, W. C. & Hung, J. J., 2014, 於 : Oncotarget. 5, 3, p. 740-753 14 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Lung Neoplasms
Neoplasm Metastasis
Neoplasms
Growth
12 引文 (Scopus)
Telomerase
Cell Proliferation
Gene Expression
Proteins
human TERT protein
2012
41 引文 (Scopus)

Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of Sp1 to inhibit lung cancer growth

Hsu, T. I., Wang, M. C., Chen, S. Y., Huang, S. T., Yeh, Y. M., Su, W. C., Chang, W. C. & Hung, J. J., 十二月 2012, 於 : Molecular Pharmacology. 82, 6, p. 1115-1128 14 p.

研究成果: 雜誌貢獻文章

Sumoylation
Lung Neoplasms
Growth
Proteins
Cyclin A2
76 引文 (Scopus)

Sp1 expression regulates lung tumor progression

Hsu, T. I., Wang, M. C., Chen, S. Y., Yeh, Y. M., Su, W. C., Chang, W. C. & Hung, J. J., 八月 30 2012, 於 : Oncogene. 31, 35, p. 3973-3988 16 p.

研究成果: 雜誌貢獻文章

Lung
Neoplasms
Proteins
Neoplasm Metastasis
Lung Neoplasms
2011
25 引文 (Scopus)

Heat shock protein 90 stabilizes nucleolin to increase mRNA stability in mitosis

Wang, S. A., Li, H. Y., Hsu, T. I., Chen, S. H., Wu, C. J., Chang, W. C. & Hung, J. J., 十二月 23 2011, 於 : Journal of Biological Chemistry. 286, 51, p. 43816-43829 14 p.

研究成果: 雜誌貢獻文章

HSP90 Heat-Shock Proteins
RNA Stability
Mitosis
Messenger RNA
Carcinogenesis
2010
9 引文 (Scopus)
trichostatin A
Cyclooxygenase 2
Lipopolysaccharides
Assays
Phosphorylation