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研究成果 2003 2018

  • 1250 引文
  • 15 h-指數
  • 25 文章
2018
1 引文 (Scopus)

Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target

Hung, C. S., Wang, S. C., Yen, Y. T., Lee, T. H., Wen, W. C. & Lin, R. K., 十月 10 2018, 於 : International Journal of Molecular Sciences. 19, 10

研究成果: 雜誌貢獻文章

biomarkers
Biomarkers
breast
lungs
Lung Neoplasms
2017
14 引文 (Scopus)

Bioactive constituents from the termite nest-derived medicinal fungus Xylaria nigripes

Chang, J. C., Hsiao, G., Lin, R. K., Kuo, Y. H., Ju, Y. M. & Lee, T. H., 一月 27 2017, 於 : Journal of Natural Products. 80, 1, p. 38-44 7 p.

研究成果: 雜誌貢獻文章

Isoptera
Fungi
Alcohols
Sleep Initiation and Maintenance Disorders
Nitric Oxide Synthase Type II

Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Lin, R. K., Hung, W. Y., Huang, Y. F., Chang, Y. J., Lin, C. H., Chen, W. Y., Chiu, S. F., Chang, S. C. & Tsai, S. F., 一月 1 2017, 於 : Oncotarget. 8, 69, p. 113431-113443 13 p.

研究成果: 雜誌貢獻文章

Colorectal Neoplasms
Cell Proliferation
Tumor Suppressor Genes
Taiwan
Survival
2016
12 引文 (Scopus)

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., 四月 15 2016, 於 : Life Sciences. 151, p. 7-14 8 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Cell Movement
Breast Neoplasms
Atlases
Assays
13 引文 (Scopus)

Angiogenesis Inhibitors and Anti-Inflammatory Agents from Phoma sp. NTOU4195

Lee, M. S., Wang, S. W., Wang, G. J., Pang, K. L., Lee, C. K., Kuo, Y. H., Cha, H. J., Lin, R. K. & Lee, T. H., 十二月 23 2016, 於 : Journal of Natural Products. 79, 12, p. 2983-2990 8 p.

研究成果: 雜誌貢獻文章

Angiogenesis Inhibitors
Macrophages
Endothelial cells
Inhibitory Concentration 50
Lipopolysaccharides
2 引文 (Scopus)
Lovastatin
Reactive Oxygen Species
Cytotoxicity
Cells
Cell death
1 引文 (Scopus)

Terpenoids from the fermented broths of coprinellus radians

Lee, M. S., Hsiao, C. J., Ju, Y. M., Kuo, Y. H., Lin, R. K. & Lee, T. H., 2016, 於 : Natural Product Communications. 11, 9, p. 1229-1230 2 p.

研究成果: 雜誌貢獻文章

Coprinellus
Terpenes
Candida albicans
terpenoids
fluorouracil
5 引文 (Scopus)

Thrombomodulin influences the survival of patients with non-metastatic colorectal cancer through epithelial-to-mesenchymal transition (EMT)

Chang, Y. J., Cheng, Y. W., Lin, R. K., Huang, C. C., Chen, W. T. L., Ke, T. W. & Wei, P. L., 八月 1 2016, 於 : PLoS One. 11, 8, e0160550.

研究成果: 雜誌貢獻文章

Thrombomodulin
Epithelial-Mesenchymal Transition
colorectal neoplasms
Colorectal Neoplasms
Survival
2015
7 引文 (Scopus)

FCGR2A promoter methylation and risks for intravenous immunoglobulin treatment responses in kawasaki disease

Kuo, H. C., Hsu, Y. W., Wu, M. S., Woon, P. Y., Wong, H. S. C., Tsai, L. J., Lin, R. K., Klahan, S., Hsieh, K. S. & Chang, W. C., 2015, 於 : Mediators of Inflammation. 2015, 564625.

研究成果: 雜誌貢獻文章

Mucocutaneous Lymph Node Syndrome
Intravenous Immunoglobulins
Methylation
Therapeutics
IgG Receptors
2014
26 引文 (Scopus)

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential

Wang, S. C., Li, Z-H., Hsu, C. H., Chang, Y. J., Chang, M. S., Wang, Y. C., Ho, Y. S., Wen, W. C. & Lin, R. K., 六月 18 2014, 於 : Journal of Agricultural and Food Chemistry. 62, 24, p. 5625-5635 11 p.

研究成果: 雜誌貢獻文章

Antrodia
Taiwanofungus camphoratus
methyltransferases
Methyltransferases
breast neoplasms
14 引文 (Scopus)

DNMT3B overexpression by deregulation of FOXO3a-mediated transcription repression and MDM2 overexpression in lung cancer

Yang, Y. C., Tang, Y. A., Shieh, J. M., Lin, R. K., Hsu, H. S. & Wang, Y. C., 2014, 於 : Journal of Thoracic Oncology. 9, 9, p. 1305-1315 11 p.

研究成果: 雜誌貢獻文章

Lung Neoplasms
Doxorubicin
Chromatin
DNA methyltransferase 3B
Forkhead Transcription Factors
38 引文 (Scopus)

Dysregulated transcriptional and post-translational control of DNA methyltransferases in cancer

Lin, R. K. & Wang, Y. C., 八月 19 2014, 於 : Cell and Bioscience. 4, 1, 46.

研究成果: 雜誌貢獻文章

Methyltransferases
DNA
Neoplasms
Carcinogenesis
Genes
2012
30 引文 (Scopus)

MDM2 overexpression deregulates the transcriptional control of RB/E2F leading to DNA methyltransferase 3A overexpression in lung cancer

Tang, Y. A., Lin, R. K., Tsai, Y. T., Hsu, H. S., Yang, Y. C., Chen, C. Y. & Wang, Y. C., 八月 15 2012, 於 : Clinical Cancer Research. 18, 16, p. 4325-4333 9 p.

研究成果: 雜誌貢獻文章

DNA (Cytosine-5-)-Methyltransferase
Lung Neoplasms
Tumor Suppressor Genes
Methylation
DNA Methylation
163 引文 (Scopus)

TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases

Hsu, C-H., Peng, K-L., Kang, M-L., Chen, Y-R., Yang, Y-C., Tsai, C-H., Chu, C-S., Jeng, Y-M., Chen, Y-T., Lin, F-M., Huang, H-D., Lu, Y-Y., Teng, Y-C., Lin, S-T., Lin, R. K., Tang, F-M., Lee, S-B., Hsu, H-M., Yu, J-C., Hsiao, P-W. 及其他1, Juan, L-J., 九月 27 2012, 於 : Cell Reports. 2, 3, p. 568-579 12 p.

研究成果: 雜誌貢獻文章

Tissue Inhibitor of Metalloproteinases
Tumors
Dioxygenases
Methylation
Cytosine
2010
102 引文 (Scopus)

Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer

Lin, R. K., Wu, C. Y., Chang, J. W., Juan, L. J., Hsu, H. S., Chen, C. Y., Lu, Y. Y., Tang, Y. A., Yang, Y. C., Yang, P. C. & Wang, Y. C., 七月 15 2010, 於 : Cancer Research. 70, 14, p. 5807-5817 11 p.

研究成果: 雜誌貢獻文章

Methyltransferases
Lung Neoplasms
DNA
Proteins
DNA (Cytosine-5-)-Methyltransferase
62 引文 (Scopus)

hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing

Lee, C-F., Ou, D. S. C., Lee, S-B., Chang, L-H., Lin, R. K., Li, Y-S., Upadhyay, A. K., Cheng, X., Wang, Y-C., Hsu, H-S., Hsiao, M., Wu, C-W. & Juan, L-J., 八月 2 2010, 於 : Journal of Clinical Investigation. 120, 8, p. 2920-2930 11 p.

研究成果: 雜誌貢獻文章

Methyltransferases
Gene Silencing
Tumor Suppressor Genes
Carcinogenesis
Cadherins
142 引文 (Scopus)

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

Lin, R. K., Hsieh, Y. S., Lin, P., Hsu, H. S., Chen, C. Y., Tang, Y. A., Lee, C. F. & Wang, Y. C., 二月 1 2010, 於 : Journal of Clinical Investigation. 120, 2, p. 521-532 12 p.

研究成果: 雜誌貢獻文章

Methyltransferases
Tumor Suppressor Genes
Carcinogens
Tobacco
Lung Neoplasms
2008
44 引文 (Scopus)

A triantennary dendritic galactoside-capped nanohybrid with a ZnS/CdSe nanoparticle core as a hydrophilic, fluorescent, multivalent probe for metastatic lung cancer cells

Chen, C. T., Munot, Y. S., Salunke, S. B., Wang, Y. C., Lin, R. K., Lin, C. C., Chen, C. C. & Liu, Y. H., 二月 22 2008, 於 : Advanced Functional Materials. 18, 4, p. 527-540 14 p.

研究成果: 雜誌貢獻文章

Galactosides
Fluorescent Dyes
lungs
cancer
Cells
31 引文 (Scopus)

Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type β-catenin nuclear accumulation in lung tumorigenesis

Tseng, R. C., Lin, R. K., Wen, C. K., Tseng, C., Hsu, H. S., Hsu, W. H. & Wang, Y. C., 七月 24 2008, 於 : Oncogene. 27, 32, p. 4488-4496 9 p.

研究成果: 雜誌貢獻文章

beta-Transducin Repeat-Containing Proteins
Catenins
Epigenomics
Carcinogenesis
Lung
2007
168 引文 (Scopus)

Alteration of DNA methyltransferases contributes to 5′CpG methylation and poor prognosis in lung cancer

Lin, R. K., Hsu, H. S., Chang, J. W., Chen, C. Y., Chen, J. T. & Wang, Y. C., 二月 2007, 於 : Lung Cancer. 55, 2, p. 205-213 9 p.

研究成果: 雜誌貢獻文章

Methyltransferases
Methylation
Lung Neoplasms
Tumor Suppressor Genes
Protein Methyltransferases
116 引文 (Scopus)

Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma

Hsu, H. S., Chen, T. P., Hung, C. H., Wen, C. K., Lin, R. K., Lee, H. C. & Wang, Y. C., 十一月 1 2007, 於 : Cancer. 110, 9, p. 2019-2026 8 p.

研究成果: 雜誌貢獻文章

Epigenomics
Methylation
Lung Neoplasms
p16 Genes
Genes
42 引文 (Scopus)

Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells

Lin, R. K., Hsu, C. H. & Wang, Y. C., 十一月 2007, 於 : Anti-Cancer Drugs. 18, 10, p. 1157-1164 8 p.

研究成果: 雜誌貢獻文章

Methyltransferases
Lung Neoplasms
Neoplasm Metastasis
CpG Islands
DNA
2005
55 引文 (Scopus)

Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer

Hsu, H. S., Wen, C. K., Tang, Y. A., Lin, R. K., Li, W. Y., Hsu, W. H. & Wang, Y. C., 八月 1 2005, 於 : Clinical Cancer Research. 11, 15, p. 5410-5416 7 p.

研究成果: 雜誌貢獻文章

Lung Neoplasms
Non-Small Cell Lung Carcinoma
Genes
Proteins
DNA Mismatch Repair
54 引文 (Scopus)

Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: An alternative pathway to non-small-cell lung cancer

Wang, Y. C., Lin, R. K., Tan, Y. H., Chen, J. T., Chen, C. Y. & Wang, Y. C., 一月 1 2005, 於 : Journal of Clinical Oncology. 23, 1, p. 154-164 11 p.

研究成果: 雜誌貢獻文章

Tumor Suppressor Protein p14ARF
Non-Small Cell Lung Carcinoma
Proteins
p53 Genes
Neoplasms
2003
108 引文 (Scopus)

Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples

Wang, Y. C., Lu, Y. P., Tseng, R. C., Lin, R. K., Chang, J. W., Chen, J. T., Shih, C. M. & Chen, C. Y., 三月 2003, 於 : Journal of Clinical Investigation. 111, 6, p. 887-895 9 p.

研究成果: 雜誌貢獻文章

Sputum
Methylation
Lung
Non-Small Cell Lung Carcinoma
Genes