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研究成果 1991 2019

2019
開啟存取
Electronic Health Records
Human Influenza
Incidence
Taiwan
Centers for Disease Control and Prevention (U.S.)

Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats

Lin, K. H., Shibu, M. A., Peramaiyan, R., Chen, Y. F., Shen, C. Y., Hsieh, Y. L., Chen, R. J., Viswanadha, V. P., Kuo, W. W. & Huang, C. Y., 一月 1 2019, 於 : Journal of Functional Foods. 52, p. 212-218 7 p.

研究成果: 雜誌貢獻文章

flavone
Cardiomegaly
flavones
hypertrophy
hypertension

CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation

Chao, C. N., Lai, C. H., Badrealam, K. F., Lo, J. F., Shen, C. Y., Chen, C. H., Chen, R. J., Viswanadha, V. P., Kuo, W. W. & Huang, C. Y., 十一月 1 2019, 於 : Journal of Cellular Physiology. 234, 11, p. 20128-20138 11 p.

研究成果: 雜誌貢獻文章

HSC70 Heat-Shock Proteins
NFATC Transcription Factors
Cardiomegaly
Lipopolysaccharides
Apoptosis
1 引文 (Scopus)

Lessons learned from isolated blunt major pancreatic injury: Surgical experience in one trauma centre

Lin, B. C., Chen, R. J. & Hwang, T. L., 一月 1 2019, 於 : Injury.

研究成果: 雜誌貢獻文章

開啟存取
Trauma Centers
Intraoperative Complications
Pancreatectomy
Wounds and Injuries
Spleen

New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury

Lu, W-J., Lin, K-H., Tseng, M-F., Yuan, K-C., Huang, H-C., Sheu, J-R. & Chen, R-J., 三月 1 2019, 於 : Journal of Cellular and Molecular Medicine. 23, 3, p. 1723-1734 12 p.

研究成果: 雜誌貢獻文章

Hemorrhagic Shock
Liver
Wounds and Injuries
Resuscitation
Therapeutics
3 引文 (Scopus)

Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats

Chen, Y. P., Sivalingam, K., Shibu, M. A., Peramaiyan, R., Day, C. H., Shen, C. Y., Lai, C. H., Chen, R. J., Viswanadha, V. P., Chen, Y. F. & Huang, C. Y., 四月 1 2019, 於 : Phytomedicine. 57, p. 1-8 8 p.

研究成果: 雜誌貢獻文章

Phosphatidylinositol 3-Kinases
Angiotensin II
Apoptosis
Hypertension
Cell Survival

Synergistic cardiac pathological hypertrophy induced by high-salt diet in IGF-IIRα cardiac-specific transgenic rats

Chang, R. L., Nithiyanantham, S., Huang, C. Y., Pai, P. Y., Chang, T. T., Hu, L. C., Chen, R. J., VijayaPadma, V., Kuo, W. W. & Huang, C. Y., 六月 1 2019, 於 : PLoS ONE. 14, 6, e0216285.

研究成果: 雜誌貢獻文章

開啟存取
Transgenic Rats
Cardiomegaly
Nutrition
hypertrophy
Rats

Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade

Chao, C. N., Lo, J. F., Khan, F. B., Day, C. H., Lai, C. H., Chen, C. H., Chen, R. J., Viswanadha, V. P., Kuo, C. H. & Huang, C. Y., 一月 1 2019, 於 : Journal of Cellular Biochemistry. 120, 10, p. 16703-16710 8 p.

研究成果: 雜誌貢獻文章

Cardiomegaly
Phosphatidylinositol 3-Kinases
Lipopolysaccharides
Modulation
Apoptosis

Two-vessel occlusion mouse model of cerebral ischemia-reperfusion

Chen, C. Y., Chen, R. J. & Lee, G. A., 三月 1 2019, 於 : Journal of Visualized Experiments. 2019, 145, e59078.

研究成果: 雜誌貢獻文章

Brain Ischemia
Reperfusion
Middle Cerebral Artery Infarction
Middle Cerebral Artery
Blood
1 引文 (Scopus)

Upregulation of IGF-IIRα intensifies doxorubicin-induced cardiac damage

Pandey, S., Kuo, W. W., Ho, T. J., Yeh, Y. L., Shen, C. Y., Chen, R. J., Chang, R. L., Pai, P. Y., Padma, V. V., Huang, C. Y. & Huang, C. Y., 一月 1 2019, 於 : Journal of Cellular Biochemistry. 120, 10, p. 16956-16966 11 p.

研究成果: 雜誌貢獻文章

Doxorubicin
Up-Regulation
Cardiomegaly
Heat-Shock Proteins
Proteins
2018
7 引文 (Scopus)
Clinical Decision Support Systems
Medical Order Entry Systems
Physicians
Health Facilities
Drug-Related Side Effects and Adverse Reactions
4 引文 (Scopus)

Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

Chen, Y. P., Kuo, W. W., Baskaran, R., Day, C. H., Chen, R. J., Wen, S. Y., Ho, T. J., Padma, V. V., Kuo, C. H. & Huang, C. Y., 四月 1 2018, 於 : Journal of Cellular Biochemistry. 119, 4, p. 3363-3372 10 p.

研究成果: 雜誌貢獻文章

Glucose Transporter Type 4
Palmitic Acid
Cardiac Myocytes
Fatty Acids
Apoptosis

Alpinate Oxyphyllae extracts enhance the longevity and homing of mesenchymal stem cells and augment their protection against senescence in H9c2 cells

Chang, Y. M., Asokan Shibu, M., Tsai, C. T., Tsai, C. C., Lin, S. L., Chang, C. C., Viswanadha, V. P., Chen, R. J., Chang, J. H. M. & Huang, C. Y., 一月 1 2018, (接受/付印) 於 : Journal of Cellular Physiology.

研究成果: 雜誌貢獻文章

Stem cells
Mesenchymal Stromal Cells
Stem Cells
Doxorubicin
CXC Chemokines

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., 十一月 14 2018, 於 : Journal of Clinical Medicine. 7, 11

研究成果: 雜誌貢獻文章

Phospholipase D
Blood Platelets
Platelet Activation
Platelet Aggregation
Thrombosis
6 引文 (Scopus)

Cardiac apoptosis induced under high glucose condition involves activation of IGF2R signaling in H9c2 cardiomyoblasts and streptozotocin-induced diabetic rat hearts

Feng, C. C., Pandey, S., Lin, C. Y., Shen, C. Y., Chang, R. L., Chang, T. T., Chen, R. J., Viswanadha, V. P., Lin, Y. M. & Huang, C. Y., 一月 1 2018, 於 : Biomedicine and Pharmacotherapy. 97, p. 880-885 6 p.

研究成果: 雜誌貢獻文章

IGF Type 2 Receptor
Streptozocin
Apoptosis
Glucose
Cardiomegaly
1 引文 (Scopus)
Colistin
Carbapenems
Taiwan
Intensive Care Units
Emergency Medicine

C-terminus of Hsc70-interacting protein (CHIP) enhances stemness properties of human Wharton’s jelly mesenchymal stem cell

Yang, C. K., Feng, C. C., Lo, J. F., Chen, J. W., Padma, V. V., Lai, C. H., Chen, T. S., Chen, R. J., Liao, P. H. & Huang, C. Y., 十一月 17 2018, 於 : Biotechnic and Histochemistry. 93, 8, p. 632-639 8 p.

研究成果: 雜誌貢獻文章

Wharton Jelly
HSC70 Heat-Shock Proteins
Mesenchymal Stromal Cells
Ubiquitin-Protein Ligases
Proto-Oncogene Proteins c-akt
2 引文 (Scopus)

Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

Huang, C. Y., Kuo, C. H., Pai, P. Y., Ho, T. J., Lin, Y. M., Chen, R. J., Tsai, F. J., Vijaya Padma, V., Kuo, W. W. & Huang, C. Y., 二月 1 2018, 於 : Data in Brief. 16, p. 521-526 6 p.

研究成果: 雜誌貢獻文章

Angiotensin II
Heart Failure
Cardiomegaly
Hypertension
Sumoylation
2 引文 (Scopus)

E4BP4 inhibits AngII-induced apoptosis in H9c2 cardiomyoblasts by activating the PI3K-Akt pathway and promoting calcium uptake

Chen, B. C., Shibu, M. A., Kuo, C. H., Shen, C. Y., Chang-Lee, S. N., Lai, C. H., Chen, R. J., Yao, C. H., Viswanadha, V. P., Liu, J. S., Chen, W. K. & Huang, C. Y., 一月 1 2018, (接受/付印) 於 : Experimental Cell Research.

研究成果: 雜誌貢獻文章

Phosphatidylinositol 3-Kinases
Angiotensin II
Apoptosis
Calcium
Insulin-Like Growth Factor II

Epithelioid Angiomyolipoma of the Liver

Huang, Y. M., Wei, P. L. & Chen, R. J., 一月 1 2018, 於 : Journal of Gastrointestinal Surgery. 22, 1, p. 175-176 2 p.

研究成果: 雜誌貢獻文章

Angiomyolipoma
Liver
4 引文 (Scopus)

Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats

Chen, W. K., Tsai, Y. L., Shibu, M. A., Shen, C. Y., Chang-Lee, S. N., Chen, R. J., Yao, C. H., Ban, B., Kuo, W. W. & Huang, C. Y., 十二月 1 2018, 於 : Aging. 10, 12, p. 4166-4174 9 p.

研究成果: 雜誌貢獻文章

Galactose
Exercise
Inflammation
Hematoxylin
Eosine Yellowish-(YS)
4 引文 (Scopus)

Fenofibrate induced PPAR alpha expression was attenuated by oestrogen receptor alpha overexpression in Hep3B cells

Jeng, L. B., Velmurugan, B. K., Hsu, H. H., Wen, S. Y., Shen, C. Y., Lin, C. H., Lin, Y. M., Chen, R. J., Kuo, W. W. & Huang, C. Y., 二月 1 2018, 於 : Environmental Toxicology. 33, 2, p. 234-247 14 p.

研究成果: 雜誌貢獻文章

Fenofibrate
PPAR alpha
Estrogen Receptor alpha
apoptosis
plasmid
3 引文 (Scopus)

GABA tea attenuates cardiac apoptosis in spontaneously hypertensive rats (SHR) by enhancing PI3K/Akt-mediated survival pathway and suppressing Bax/Bak dependent apoptotic pathway

Chen, B. C., Hung, M. Y., Wang, H. F., Yeh, L. J., Pandey, S., Chen, R. J., Chang, R. L., Viswanadha, V. P., Lin, K. H. & Huang, C. Y., 一月 1 2018, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻文章

apoptosis
tea
Tea
Inbred SHR Rats
Phosphatidylinositol 3-Kinases
13 引文 (Scopus)

HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy

Huang, C. Y., Lee, F. L., Peng, S. F., Lin, K. H., Chen, R. J., Ho, T. J., Tsai, F. J., Padma, V. V., Kuo, W. W. & Huang, C. Y., 二月 2018, 於 : Journal of Cellular Physiology. 233, 2, p. 979-989

研究成果: 雜誌貢獻文章

IGF Type 2 Receptor
Phosphorylation
Extracellular Signal-Regulated MAP Kinases
Cardiac Myocytes
Angiotensin II
9 引文 (Scopus)

Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy

Huang, C. Y., Kuo, C. H., Pai, P. Y., Ho, T. J., Lin, Y. M., Chen, R. J., Tsai, F. J., Vijaya Padma, V., Kuo, W. W. & Huang, C. Y., 四月 15 2018, 於 : International Journal of Cardiology. 257, p. 283-290

研究成果: 雜誌貢獻文章

Sumoylation
Cardiomegaly
Up-Regulation
Hypertension
Heart Failure
2 引文 (Scopus)

Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest

Lu, W. J., Wu, G. J., Chen, R. J., Chang, C. C., Lien, L. M., Chiu, C. C., Tseng, M. F., Huang, L. T. & Lin, K. H., 八月 1 2018, 於 : Food and Function. 9, 8, p. 4500-4507 8 p.

研究成果: 雜誌貢獻文章

Cell Cycle Checkpoints
Glioma
cell growth
licorice
neoplasms
6 引文 (Scopus)

Lipoteichoic acid upregulates plasminogen activator inhibitor-1 expression in parapneumonic effusions

Lee, K. L., Chen, W. L., Chen, R. J., Lai, K. S. & Chung, C. L., 一月 1 2018, 於 : Respirology. 23, 1, p. 89-95 7 p.

研究成果: 雜誌貢獻文章

Plasminogen Activator Inhibitor 1
Up-Regulation
Gram-Positive Bacteria
Toll-Like Receptor 2
lipoteichoic acid
6 引文 (Scopus)

Lupeol alters ER stress-signaling pathway by downregulating ABCG2 expression to induce Oxaliplatin-resistant LoVo colorectal cancer cell apoptosis

Chen, M. C., Hsu, H. H., Chu, Y. Y., Cheng, S. F., Shen, C. Y., Lin, Y. J., Chen, R. J., Viswanadha, V. P., Lin, Y. M. & Huang, C. Y., 一月 1 2018, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻文章

oxaliplatin
Endoplasmic Reticulum Stress
apoptosis
Colorectal Neoplasms
cancer
19 引文 (Scopus)

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., 九月 15 2018, 於 : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

研究成果: 雜誌貢獻文章

Glioma
Isocitrate Dehydrogenase
Histology
Phenotype
Glioblastoma
10 引文 (Scopus)

Oolong tea prevents cardiomyocyte loss against hypoxia by attenuating p-JNK mediated hypertrophy and enhancing P-IGF1R, p-akt, and p-Badser136 activity and by fortifying NRF2 antioxidation system

Shibu, M. A., Kuo, C. H., Chen, B. C., Ju, D. T., Chen, R. J., Lai, C. H., Huang, P. J., Viswanadha, V. P., Kuo, W. W. & Huang, C. Y., 二月 1 2018, 於 : Environmental Toxicology. 33, 2, p. 220-233

研究成果: 雜誌貢獻文章

tea
Tea
hypoxia
Cardiac Myocytes
Hypertrophy
3 引文 (Scopus)

Overexpression of IGF-IIRα regulates cardiac remodeling and aggravates high salt induced apoptosis and fibrosis in transgenic rats

Chang, R. L., Nithiyanantham, S., Kuo, W. W., Pai, P. Y., Chang, T. T., Lai, C. H., Chen, R. J., Vijaya Padma, V., Huang, C. Y. & Huang, C. Y., 一月 1 2018, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻文章

Transgenic Rats
apoptosis
Rats
Fibrosis
Salts
1 引文 (Scopus)
Gastrectomy
Coronary Disease
Morbid Obesity
Comorbidity
Diabetes Mellitus
12 引文 (Scopus)

Synergistic effect of HIF-1α and FoxO3a trigger cardiomyocyte apoptosis under hyperglycemic ischemia condition

Chen, Y. F., Pandey, S., Day, C. H., Chen, Y. F., Jiang, A. Z., Ho, T. J., Chen, R. J., Padma, V. V., Kuo, W. W. & Huang, C. Y., 四月 2018, 於 : Journal of Cellular Physiology. 233, 4, p. 3660-3671

研究成果: 雜誌貢獻文章

Cardiac Myocytes
Ischemia
Apoptosis
Glucose
Polymerase chain reaction
1 引文 (Scopus)
Amphotericin B
Drug Therapy
Neoplasms
Ethanol
Cinnamomum
19 引文 (Scopus)

The multifaceted link between inflammation and human diseases

Rajendran, P., Chen, Y. F., Chen, Y. F., Chung, L. C., Tamilselvi, S., Shen, C. Y., Day, C. H., Chen, R. J., Viswanadha, V. P., Kuo, W. W. & Huang, C. Y., 一月 1 2018, (接受/付印) 於 : Journal of Cellular Physiology.

研究成果: 雜誌貢獻文章

Inflammation
Tissue
Phagocytes
Lymphocytes
Macrophages
4 引文 (Scopus)

The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice

Lin, K. H., Chiu, C. H., Kuo, W. W., Ju, D. T., Shen, C. Y., Chen, R. J., Lin, C. C., Viswanadha, V. P., Liu, J. S., Huang, R. F. S. & Huang, C. Y., 一月 2018, 於 : Environmental Toxicology. 33, 1, p. 83-92

研究成果: 雜誌貢獻文章

apoptosis
Folic Acid
Cardiac Myocytes
Alzheimer Disease
Apoptosis
2 引文 (Scopus)

Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs

Feng, C. C., Liao, P. H., Tsai, H. I., Cheng, S. M., Yang, L. Y., PadmaViswanadha, V., Pan, L. F., Chen, R. J., Lo, J. F. & Huang, C. Y., 一月 1 2018, 於 : International Journal of Medical Sciences. 15, 13, p. 1537-1546 10 p.

研究成果: 雜誌貢獻文章

HSC70 Heat-Shock Proteins
Imaginal Discs
Cardiomegaly
Isoproterenol
Proteolysis
2017
8 引文 (Scopus)

Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Chang, Y. M., Chang, H. H., Tsai, C. C., Lin, H. J., Ho, T. J., Ye, C. X., Chiu, P. L., Chen, Y. S., Chen, R. J., Huang, C. Y. & Lin, C. C., 三月 31 2017, 於 : BMC Complementary and Alternative Medicine. 17, 1, 184.

研究成果: 雜誌貢獻文章

Alpinia
Nerve Regeneration
Schwann Cells
Sciatic Nerve
Phosphatidylinositol 3-Kinases
7 引文 (Scopus)
gemcitabine
Chemotherapy
Tumor Burden
Pancreatic Neoplasms
Heterografts
Enterobacter cloacae
Carbapenems
Klebsiella pneumoniae
Taiwan
Intensive Care Units

Development of benzimidazole derivatives as novel anti-platelet drugs

Yao, W. C., Yuan, L. T., Yang, W. B., Hsia, C. H., Huang, L. T., Lee, T. Y., Sheu, J. R., Lu, W-J., Jayakumar, T. & Chen, R. J., 一月 1 2017, 於 : Current Pharmaceutical Biotechnology. 18, 7, p. 594-605 12 p.

研究成果: 雜誌貢獻文章

Thrombin
Blood Platelets
Platelet Aggregation
Pharmaceutical Preparations
Epinephrine
5 引文 (Scopus)

E2/ER β enhances calcineurin protein degradation and PI3k/Akt/MDM2 signal transduction to inhibit ISO-induced myocardial cell apoptosis

Lin, K. H., Kuo, W. W., Shibu, M. A., Day, C. H., Hsieh, Y. L., Chung, L. C., Chen, R. J., Wen, S. Y., Viswanadha, V. P. & Huang, C. Y., 四月 24 2017, 於 : International Journal of Molecular Sciences. 18, 4, 892.

研究成果: 雜誌貢獻文章

estrogens
Signal transduction
Calcineurin
apoptosis
Cell death
2 引文 (Scopus)

Elevated Phosphate Levels Trigger Autophagy-Mediated Cellular Apoptosis in H9c2 Cardiomyoblasts

Liu, Y. L., Lin, K. H., Tamilselvi, S., Chen, W. K., Shen, C. Y., Chen, R. J., Day, C. H., Wu, H. C., Viswanadha, V. P. & Huang, C. Y., 九月 30 2017, (接受/付印) 於 : CardioRenal Medicine. p. 31-40 10 p.

研究成果: 雜誌貢獻文章

Autophagy
Phosphates
Apoptosis
Fluorescein-5-isothiocyanate
Annexin A5
9 引文 (Scopus)

Enhancement of beta-catenin in cardiomyocytes suppresses survival protein expression but promotes apoptosis and fibrosis

Lin, J. C., Kuo, W. W., Baskaran, R., Chen, M. C., Ho, T. J., Chen, R. J., Chen, Y. F., Padma, V. V., Lay, I. S. & Huang, C. Y., 2017, 於 : Cardiology Journal. 24, 2, p. 195-205 11 p.

研究成果: 雜誌貢獻文章

Catenins
beta Catenin
Cardiac Myocytes
Fibrosis
Apoptosis
2 引文 (Scopus)

High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte

Wen, S. Y., Velmurugan, B. K., Day, C. H., Shen, C. Y., Chun, L. C., Tsai, Y. C., Lin, Y. M., Chen, R. J., Kuo, C. H. & Huang, C. Y., 2017, (接受/付印) 於 : Journal of Cellular Physiology.

研究成果: 雜誌貢獻文章

Palmitic Acid
HDL Lipoproteins
Cardiac Myocytes
Energy Metabolism
Metabolic Networks and Pathways

How motorcycle helmets affect trauma mortality: Clinical and policy implications

Lee, J. L., Chen, T. C., Huang, H. C. & Chen, R. J., 八月 18 2017, 於 : Traffic Injury Prevention. 18, 6, p. 666-671 6 p.

研究成果: 雜誌貢獻文章

Motorcycles
Head Protective Devices
motorcycle
trauma
mortality
5 引文 (Scopus)

Identification of epidermal growth factor receptor-positive glioblastoma using lipid-encapsulated targeted superparamagnetic iron oxide nanoparticles in vitro

Chen, H. L., Hsu, F. T., Kao, Y. C. J., Liu, H. S., Huang, W. Z., Lu, C. F., Tsai, P. H., Ali, A. A. A., Lee, G. A., Chen, R. J. & Chen, C. Y., 十一月 22 2017, 於 : Journal of Nanobiotechnology. 15, 1, 86.

研究成果: 雜誌貢獻文章

Glioblastoma
Iron oxides
Epidermal Growth Factor Receptor
Nanoparticles
Lipids
3 引文 (Scopus)
Diabetes Mellitus
Cohort Studies
Mortality
Odds Ratio
Population
4 引文 (Scopus)

Increased β-catenin accumulation and nuclear translocation are associated with concentric hypertrophy in cardiomyocytes

Lee, C. Y., Kuo, W. W., Baskaran, R., Day, C. H., Pai, P. Y., Lai, C. H., Chen, Y. F., Chen, R. J., Padma, V. V. & Huang, C. Y., 十一月 1 2017, 於 : Cardiovascular Pathology. 31, p. 9-16 8 p.

研究成果: 雜誌貢獻文章

Catenins
Cardiac Myocytes
Hypertrophy
Infarction
Cardiomegaly