Ming-Hsien Chien

2020

Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer

Yang, Y-C., Pan, K-F., Lee, W-J., Chang, J-H., Tan, P., Gu, C-C., Chang, W-M., Yang, S-F., Hsiao, M., Hua, K-T. & Chien, M-H., 六月 19 2020, 於 : Cancer Research.

研究成果: 雜誌貢獻 › 文章

Dual targeting of the p38 MAPK‐HO‐1 axis and cIAP1/XIAP by demethoxycurcumin triggers caspase‐mediated apoptotic cell death in oral squamous cell carcinoma cells

Chien, M. H., Yang, W. E., Yang, Y. C., Ku, C. C., Lee, W. J., Tsai, M. Y., Lin, C. W. & Yang, S. F., 三月 2020, 於 : Cancers. 12, 3, 703.

研究成果: 雜誌貢獻 › 文章

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2019

Association of EGFR mutations and HMGB1 genetic polymorphisms in lung adenocarcinoma patients

Wu, Y. L., Chien, M. H., Chou, Y. E., Chang, J. H., Liu, T. C., Tsao, T. C. Y., Chou, M. C. & Yang, S. F., 一月 1 2019, 於 : Journal of Cancer. 10, 13, p. 2907-2914 8 p.

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2 引文斯高帕斯（Scopus）

Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response

Hung, W. Y., Chang, J. H., Cheng, Y., Cheng, G. Z., Huang, H. C., Hsiao, M., Chung, C. L., Lee, W. J. & Chien, M. H., 八月 1 2019, 於 : Cell Death and Disease. 10, 8, 538.

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1 引文斯高帕斯（Scopus）

Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis

Su, C. W., Chang, Y. C., Chien, M. H., Hsieh, Y. H., Chen, M. K., Lin, C. W. & Yang, S. F., 十一月 1 2019, 於 : Cell Death and Disease. 10, 11, 793.

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5 引文斯高帕斯（Scopus）

Mesenchymal stem cells restore the sperm motility from testicular torsion-detorsion injury by regulation of glucose metabolism in sperm

Hsiao, C. H., Ji, A. T. Q., Chang, C. C., Chien, M. H., Lee, L. M. & Ho, J. H. C., 八月 24 2019, 於 : Stem Cell Research and Therapy. 10, 1, 270.

研究成果: 雜誌貢獻 › 文章

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1 引文斯高帕斯（Scopus）

Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses

Wu, S. Y., Wen, Y. C., Ku, C. C., Yang, Y. C., Chow, J. M., Yang, S. F., Lee, W. J. & Chien, M. H., 八月 31 2019, 於 : Journal of Biomedical Science. 26, 1, 63.

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2 引文斯高帕斯（Scopus）

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis

Chien, M. H., Lin, Y. W., Wen, Y. C., Yang, Y. C., Hsiao, M., Chang, J. L., Huang, H. C. & Lee, W. J., 六月 10 2019, 於 : Journal of Experimental and Clinical Cancer Research. 38, 1, 246.

研究成果: 雜誌貢獻 › 文章

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7 引文斯高帕斯（Scopus）

2018

Associations of genetic variations of the endothelial nitric oxide synthase gene and environmental carcinogens with oral cancer susceptibility and development

Su, C. W., Chien, M. H., Lin, C. W., Chen, M. K., Chow, J. M., Chuang, C. Y., Chou, C. H., Liu, Y. C. & Yang, S. F., 九月 1 2018, 於 : Nitric Oxide - Biology and Chemistry. 79, p. 1-7 7 p.

研究成果: 雜誌貢獻 › 文章

10 引文斯高帕斯（Scopus）

Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway

Wang, S. C., Chow, J. M., Chien, M. H., Lin, C. W., Chen, H. Y., Hsiao, P. C. & Yang, S. F., 一月 1 2018, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻 › 文章

15 引文斯高帕斯（Scopus）

Dopamine receptor D2 genetic variations is associated with the risk and clinicopathological variables of urothelial cell carcinoma in a taiwanese population

Tung, M. C., Wen, Y. C., Wang, S. S., Lin, Y. W., Liu, Y. C., Yang, S. F. & Chien, M. H., 七月 30 2018, 於 : International Journal of Medical Sciences. 15, 11, p. 1187-1193 7 p.

研究成果: 雜誌貢獻 › 文章

2 引文斯高帕斯（Scopus）

Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses

Chang, J. H., Cheng, C. W., Yang, Y. C., Chen, W. S., Hung, W. Y., Chow, J. M., Chen, P. S., Hsiao, M., Lee, W. J. & Chien, M. H., 八月 22 2018, 於 : Journal of Experimental and Clinical Cancer Research. 37, 1, 199.

研究成果: 雜誌貢獻 › 文章

16 引文斯高帕斯（Scopus）

Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities

Hung, W. Y., Chang, J. H., Cheng, Y., Chen, C. K., Chen, J. Q., Hua, K. T., Cheng, C. W., Hsiao, M., Chung, C. L., Lee, W. J. & Chien, M. H., 一月 1 2018, 於 : Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 51, 1, p. 337-355 19 p.

研究成果: 雜誌貢獻 › 文章

4 引文斯高帕斯（Scopus）

Melatonin attenuates osteosarcoma cell invasion by suppression of C-C motif chemokine ligand 24 through inhibition of the c-Jun N-terminal kinase pathway

Lu, K. H., Su, S. C., Lin, C. W., Hsieh, Y. H., Lin, Y. C., Chien, M. H., Reiter, R. J. & Yang, S. F., 一月 1 2018, (接受/付印) 於 : Journal of Pineal Research.

研究成果: 雜誌貢獻 › 文章

16 引文斯高帕斯（Scopus）

Niclosamide, an oral antihelmintic drug, exhibits antimetastatic activity in hepatocellular carcinoma cells through downregulating twist-mediated CD10 expression

Chien, M. H., Ho, Y. C., Yang, S. F., Yang, Y. C., Lai, S. Y., Chen, W. S., Chen, M. J. & Yeh, C. B., 一月 1 2018, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻 › 文章

2 引文斯高帕斯（Scopus）

Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress

Yang, Y. C., Chien, M. H., Liu, H. Y., Chang, Y. C., Chen, C. K., Lee, W. J., Kuo, T. C., Hsiao, M., Hua, K. T. & Cheng, T. Y., 五月 1 2018, 於 : Cancer Letters. 421, p. 28-40 13 p.

研究成果: 雜誌貢獻 › 文章

12 引文斯高帕斯（Scopus）

N-α-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas

Chien, M. H., Lee, W. J., Yang, Y. C., Tan, P., Pan, K. F., Liu, Y. C., Tsai, H. C., Hsu, C. H., Wen, Y. C., Hsiao, M. & Hua, K. T., 十月 1 2018, 於 : Cancer Letters. 433, p. 86-98 13 p.

研究成果: 雜誌貢獻 › 文章

8 引文斯高帕斯（Scopus）

Significant Effect of Acupressure in Elevating Blood Stem Cell Factor during Chemotherapy in Patients with Gynecologic Cancer

Shih, Y. W., Yang, S. F., Chien, M. H., Chang, C. W., Chang, V. H. S. & Tsai, H. T., 十二月 1 2018, 於 : Journal of Nursing Research. 26, 6, p. 411-419 9 p.

研究成果: 雜誌貢獻 › 文章

Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells

Wang, S. W., Chen, Y. R., Chow, J. M., Chien, M. H., Yang, S. F., Wen, Y. C., Lee, W. J. & Tseng, T. H., 一月 1 2018, (接受/付印) 於 : Molecular Carcinogenesis.

研究成果: 雜誌貢獻 › 文章

5 引文斯高帕斯（Scopus）

The disruption of the β-catenin/TCF-1/STAT3 signaling axis by 4-acetylantroquinonol b inhibits the tumorigenesis and cancer stem-cell-like properties of glioblastoma cells, in vitro and in vivo

Liu, H. W., Su, Y-K., Bamodu, O. A., Hueng, D. Y., Lee, W. H., Huang, C. C., Deng, L., Hsiao, M., Chien, M. H., Yeh, C. T. & Lin, C. M., 十二月 1 2018, 於 : Cancers. 10, 12, 491.

研究成果: 雜誌貢獻 › 文章

9 引文斯高帕斯（Scopus）

2017

3′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma

Hua, K. T., Liu, Y. F., Hsu, C. L., Cheng, T. Y., Yang, C. Y., Chang, J. S., Lee, W. J., Hsiao, M., Juan, H. F., Chien, M. H. & Yang, S. F., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 4466.

研究成果: 雜誌貢獻 › 文章

27 引文斯高帕斯（Scopus）

A Fas Ligand (FasL)-fused humanized antibody against tumor-Associated glycoprotein 72 selectively exhibits the cytotoxic effect against oral cancer cells with a low FasL/Fas ratio

Chien, M. H., Chang, W. M., Lee, W. J., Chang, Y. C., Lai, T. C., Chan, D. V., Sharma, R., Lin, Y. F. & Hsiao, M., 六月 1 2017, 於 : Molecular Cancer Therapeutics. 16, 6, p. 1102-1113 12 p.

研究成果: 雜誌貢獻 › 文章

5 引文斯高帕斯（Scopus）

Corrigendum to "Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells" [383 (2016) 282-294]

Kuo, T. C., Chen, C. K., Hua, K. T., Yu, P., Lee, W. J., Chen, M. W., Jeng, Y. M., Chien, M. H., Kuo, K. T., Hsiao, M. & Kuo, M. L., 2017, (接受/付印) 於 : Cancer Letters.

研究成果: 雜誌貢獻 › 文章

Genetic variations of melatonin receptor type 1a are associated with the clinicopathologic development of urothelial cell carcinoma

Lin, Y. W., Wang, S. S., Wen, Y. C., Tung, M. C., Lee, L. M., Yang, S. F. & Chien, M. H., 九月 4 2017, 於 : International Journal of Medical Sciences. 14, 11, p. 1130-1135 6 p.

研究成果: 雜誌貢獻 › 文章

2 引文斯高帕斯（Scopus）

KSRP suppresses cell invasion and metastasis through miR-23a-mediated EGR3 mRNA degradation in non-small cell lung cancer

Chien, M. H., Lee, W. J., Yang, Y. C., Li, Y. L., Chen, B. R., Cheng, T. Y., Yang, P. W., Wang, M. Y., Jan, Y. H., Lin, Y. K., Lee, J. M., Hsiao, M., Chen, J. S. & Hua, K. T., 十月 1 2017, 於 : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1860, 10, p. 1013-1024 12 p.

研究成果: 雜誌貢獻 › 文章

10 引文斯高帕斯（Scopus）

Overexpression of carbonic anhydrase IX induces cell motility by activating matrix metalloproteinase-9 in human oral squamous cell carcinoma cells

Yang, J. S., Lin, C. W., Hsieh, Y. H., Chien, M. H., Chuang, C. Y. & Yang, S. F., 2017, 於 : Oncotarget. 8, 47, p. 83088-83099 12 p.

研究成果: 雜誌貢獻 › 文章

16 引文斯高帕斯（Scopus）

Quercetin simultaneously induces G₀/G₁-phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells

Chang, J. L., Chow, J. M., Chang, J. H., Wen, Y-C., Lin, Y. W., Yang, S. F., Lee, W. J. & Chien, M. H., 2017, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻 › 文章

10 引文斯高帕斯（Scopus）

Quercetin suppresses the metastatic ability of lung cancer through inhibiting Snail-dependent Akt activation and Snail-independent ADAM9 expression pathways

Chang, J. H., Lai, S. L., Chen, W. S., Hung, W. Y., Chow, J. M., Hsiao, M., Lee, W. J. & Chien, M. H., 十月 1 2017, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 10, p. 1746-1758 13 p.

研究成果: 雜誌貢獻 › 文章

25 引文斯高帕斯（Scopus）

Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer

Kao, S. J., Lee, W. J., Chang, J. H., Chow, J. M., Chung, C. L., Hung, W. Y. & Chien, M. H., 四月 1 2017, 於 : Environmental Toxicology. 32, 4, p. 1426-1438

研究成果: 雜誌貢獻 › 文章

25 引文斯高帕斯（Scopus）

The STAT3-miRNA-92-Wnt signaling pathway regulates spheroid formation and malignant progression in ovarian cancer

Chen, M. W., Yang, S. T., Chien, M. H., Hua, K. T., Wu, C. J., Hsiao, S. M., Lin, H., Hsiao, M., Su, J. L. & Wei, L. H., 四月 15 2017, 於 : Cancer Research. 77, 8, p. 1955-1967 13 p.

研究成果: 雜誌貢獻 › 文章

52 引文斯高帕斯（Scopus）

Tricetin induces apoptosis of human leukemic HL-60 cells through a reactive oxygen species-mediated c-jun N-terminal kinase activation pathway

Chien, M. H., Chow, J. M., Lee, W. J., Chen, H. Y., Tan, P., Wen, Y. C., Lin, Y. W., Hsiao, P. C. & Yang, S. F., 八月 1 2017, 於 : International Journal of Molecular Sciences. 18, 8, 1667.

研究成果: 雜誌貢獻 › 文章

9 引文斯高帕斯（Scopus）

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Chien, M. H., Lee, T. H., Lee, W. J., Yeh, Y. H., Li, T. K., Wang, P. C., Chen, J. J., Chow, J. M., Lin, Y. W., Hsiao, M., Wang, S. W. & Hua, K. T., 三月 1 2017, 於 : Cancer Letters. 388, p. 249-261 13 p.

研究成果: 雜誌貢獻 › 文章

6 引文斯高帕斯（Scopus）

2016

Akt activation correlates with snail expression and potentially determines the recurrence of prostate cancer in patients at stage T2 after a radical prostatectomy

Chen, W. Y., Hua, K. T., Lee, W. J., Lin, Y. W., Liu, Y. N., Chen, C. L., Wen, Y-C. & Chien, M. H., 八月 1 2016, 於 : International Journal of Molecular Sciences. 17, 8, 1194.

研究成果: 雜誌貢獻 › 文章

1 引文斯高帕斯（Scopus）

Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells

Kuo, T. C., Chen, C. K., Hua, K. T., Yu, P., Lee, W-J., Chen, M. W., Jeng, Y. M., Chien, M-H., Kuo, K., Hsiao, M. & Kuo, M. L., 十二月 28 2016, 於 : Cancer Letters. 383, 2, p. 282-294 13 p.

研究成果: 雜誌貢獻 › 文章

23 引文斯高帕斯（Scopus）

Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21^WAF1/CIP1 expression

Tseng, T. H., Chien, M. H., Lin, W. L., Wen, Y-C., Chow, J. M., Chen, C. K., Kuo, T. C. & Lee, W. J., 2016, (接受/付印) 於 : Environmental Toxicology.

研究成果: 雜誌貢獻 › 文章

46 引文斯高帕斯（Scopus）

Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis

Lin, C. W., Yang, W. E., Lee, W. J., Hua, K. T., Hsieh, F. K., Hsiao, M., Chen, C. C., Chow, J. M., Chen, M. K., Yang, S. F. & Chien, M. H., 七月 1 2016, 於 : Carcinogenesis. 37, 7, p. 712-722 11 p.

研究成果: 雜誌貢獻 › 文章

35 引文斯高帕斯（Scopus）

Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity

Lin, Y. W., Lee, L. M., Lee, W. J., Chu, C. Y., Tan, P., Yang, Y. C., Chen, W. Y., Yang, S. F., Hsiao, M. & Chien, M. H., 四月 1 2016, 於 : Journal of Pineal Research. 60, 3, p. 277-290 14 p.

研究成果: 雜誌貢獻 › 文章

86 引文斯高帕斯（Scopus）

Melatonin suppresses TPA-induced metastasis by downregulating matrix metalloproteinase-9 expression through JNK/SP-1 signaling in nasopharyngeal carcinoma

Ho, H. Y., Lin, C. W., Chien, M. H., Reiter, R. J., Su, S. C., Hsieh, Y. H. & Yang, S. F., 十一月 1 2016, 於 : Journal of Pineal Research. 61, 4, p. 479-492 14 p.

研究成果: 雜誌貢獻 › 文章

66 引文斯高帕斯（Scopus）

Plasma levels of soluble intercellular adhesion molecule-1 as a biomarker for disease severity of patients with community-acquired pneumonia

Chang, P. Y., Tsao, S. M., Chang, J. H., Chien, M-H., Hung, W. Y., Huang, Y. W. & Yang, S. F., 十二月 1 2016, 於 : Clinica Chimica Acta. 463, p. 174-180 7 p.

研究成果: 雜誌貢獻 › 文章

3 引文斯高帕斯（Scopus）

Plasma monocyte chemoattractant protein-1 level as a predictor of the severity of community-acquired pneumonia

Yong, K. K., Chang, J. H., Chien, M. H., Tsao, S. M., Yu, M. C., Bai, K. J., Tsao, T. C. Y. & Yang, S. F., 一月 29 2016, 於 : International Journal of Molecular Sciences. 17, 2

研究成果: 雜誌貢獻 › 文章

9 引文斯高帕斯（Scopus）

Utility of plasma osteopontin levels in management of community-acquired pneumonia

Chang, J. H., Hung, W. Y., Bai, K. J., Yang, S. F. & Chien, M. H., 八月 10 2016, 於 : International Journal of Medical Sciences. 13, 9, p. 673-679 7 p.

研究成果: 雜誌貢獻 › 文章

2015

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

Wen, Y-C., Lee, W. J., Tan, P., Yang, S. F., Hsiao, M., Lee, L. M. & Chien, M. H., 2015, 於 : Oncotarget. 6, 25, p. 21120-21136 17 p.

研究成果: 雜誌貢獻 › 文章

46 引文斯高帕斯（Scopus）

Erratum: Terminalia catappa Exerts Antimetastatic Effects on Hepatocellular Carcinoma through Transcriptional Inhibition of Matrix Metalloproteinase-9 by Modulating NF- B and AP-1 Activity (Evidence-based Complementary and Alternative Medicine 2012:11 (2012))

Yeh, C. B., Hsieh, M. J., Hsieh, Y. S., Chien, M. H., Lin, P. Y., Chiou, H. L. & Yang, S. F., 2015, 於 : Evidence-based Complementary and Alternative Medicine. 2015, 326234.

研究成果: 雜誌貢獻 › 文章

G2/M cell cycle arrest and tumor selective apoptosis of acute leukemia cells by a promising benzophenone thiosemicarbazone compound

Cabrera, M., Gomez, N., Lenicov, F. R., Echeverría, E., Shayo, C., Moglioni, A., Fernández, N., Davio, C. & Chien, M. H., 九月 11 2015, 於 : PLoS One. 10, 9, 0136878.

研究成果: 雜誌貢獻 › 文章

18 引文斯高帕斯（Scopus）

Interactions between environmental factors and melatonin receptor type 1A polymorphism in relation to oral cancer susceptibility and clinicopathologic development

Lin, F. Y., Lin, C. W., Yang, S. F., Lee, W. J., Lin, Y. W., Lee, L. M., Chang, J. L., Weng, W. C., Lin, C. H. & Chien, M. H., 三月 25 2015, 於 : PLoS One. 10, 3, e0121677.

研究成果: 雜誌貢獻 › 文章

13 引文斯高帕斯（Scopus）

Keap1-Nrf2 interaction suppresses cell motility in lung adenocarcinomas by targeting the S100P protein

Chien, M. H., Lee, W. J., Hsieh, F. K., Li, C. F., Cheng, T. Y., Wang, M. Y., Chen, J. S., Chow, J. M., Jan, Y. H., Hsiao, M., Hua, K. T. & Kuo, M. L., 十月 15 2015, 於 : Clinical Cancer Research. 21, 20, p. 4719-4732 14 p.

研究成果: 雜誌貢獻 › 文章

24 引文斯高帕斯（Scopus）

Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress

Lee, W. J., Chien, M. H., Chow, J. M., Chang, J. L., Wen, Y-C., Lin, Y. W., Cheng, C. W., Lai, G. M., Hsiao, M. & Lee, L. M., 五月 27 2015, 於 : Scientific Reports. 5, 10420.

研究成果: 雜誌貢獻 › 文章

32 引文斯高帕斯（Scopus）

Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft

Lee, W-J., Hsiao, M., Chang, J. L., Yang, S. F., Tseng, T. H., Cheng, C-W., Chow, J-M., Lin, K. H., Lin, Y. W., Liu, C. C., Lee, L-M. & Chien, M-H., 七月 15 2015, 於 : Archives of Toxicology. 89, 7, p. 1103-1117 15 p.

研究成果: 雜誌貢獻 › 文章

47 引文斯高帕斯（Scopus）

RAGE gene polymorphism and environmental factor in the risk of oral cancer

Su, S., Chien, M., Lin, C., Chen, M. & Yang, S., 三月 16 2015, 於 : Journal of Dental Research. 94, 3, p. 403-411 9 p.

研究成果: 雜誌貢獻 › 文章

30 引文斯高帕斯（Scopus）

The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer

Hsiao, S. M., Chen, M. W., Chen, C. A., Chien, M. H., Hua, K. T., Hsiao, M., Kuo, M. L. & Wei, L. H., 十二月 1 2015, 於 : Annals of Surgical Oncology. 22, p. 1556-1565 10 p.

研究成果: 雜誌貢獻 › 文章

14 引文斯高帕斯（Scopus）

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