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指紋 查看啟用 Lien-Szu Wu 的研究主題。這些主題標籤來自此人的作品。共同形成了獨特的指紋。

  • 2 類似的檔案
Motor Neurons Medicine & Life Sciences
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
Neurons Chemical Compounds
DNA-Binding Proteins Medicine & Life Sciences
Frontotemporal Lobar Degeneration Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
TDP-43 Proteinopathies Medicine & Life Sciences
RNA-Binding Proteins Medicine & Life Sciences

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研究成果 2008 2016

  • 641 引文
  • 7 h-指數
  • 7 文章
22 引文 (Scopus)

Structural analysis of disease-related TDP-43 D169G mutation: Linking enhanced stability and caspase cleavage efficiency to protein accumulation

Chiang, C. H., Grauffel, C., Wu, L. S., Kuo, P. H., Doudeva, L. G., Lim, C., Shen, C. K. J. & Yuan, H. S., 二月 17 2016, 於 : Scientific Reports. 6, 21581.

研究成果: 雜誌貢獻文章

開啟存取
Caspases
Amyotrophic Lateral Sclerosis
Mutation
Proteins
Caspase 3
16 引文 (Scopus)

Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS

Dong, H., Xu, L., Wu, L., Wang, X., Duan, W., Li, H. & Li, C., 七月 11 2014, 於 : Neuroscience. 272, p. 141-153 13 p.

研究成果: 雜誌貢獻文章

Curcumin
DNA-Binding Proteins
Motor Neurons
Action Potentials
Oxidative Stress
7 引文 (Scopus)
開啟存取
Motor Neurons
Cell death
Amino Acid Substitution
Neurons
Cell Death
86 引文 (Scopus)
開啟存取
TDP-43 Proteinopathies
Amyotrophic Lateral Sclerosis
Motor Neurons
Neurons
Spinal Cord
175 引文 (Scopus)

TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis

Wu, L. S., Cheng, W., Hou, S. C., Yan, Y. T., Jiang, S. T. & Shen, C. K. J., 一月 1 2010, 於 : Genesis. 48, 1, p. 56-62 7 p.

研究成果: 雜誌貢獻文章

Embryonic Development
Biological Phenomena
Neuronal Plasticity
Gene Targeting
Amyotrophic Lateral Sclerosis